Nervous disorders

Uses and Economic Aspects. Magnesium bromide is used in medicine as a sedative in treatment of nervous disorders, in electrolyte paste for magnesium dry cells, and as a reagent in organic synthesis reactions. The price of magnesium bromide hexahydrate in January 1995 was 5.51/kg (33). 

The toxic effects of mercury have long been known,and the use of HgCl, as a poison has already been mentioned. The use of mercury salts in the production of felt for hats and the dust generated in ill-ventilated workshops by the subsequent drying process, led to the nervous disorder known as hatter s shakes and possibly also to the expression mad as a hatter . 

Storage products derived from complex glycoproteins have been identified in the brains of Springer spaniels suilering from a progressive nervous disorder. F.a.b.-m.s. of the native compounds and their acetylated and permethylated derivatives allowed the assignment of structures 26, 27, and 28. 

Diabetes-associated peripheral vascular and nervous disorders ... 

Under chronic intoxication, late skin porphyria is added to the above diseases. This syndrome is characterized by increased excretion of carboxylated porphyrins, coverlet pigmentation, photosensitivity, intes-tinal and nervous disorders. Toxic carboxylated porphyrins and ions of iron, not included into porphyrin structure, are accumulated in the cells of various organs. 

Symptoms of exposure May cause weakness, confusion, depression of central nervous system, dyspnea, weak pulse, and respiratory failure. May irritate eyes and mucous membranes. Contact with skin may cause burns and dermatitis. Chronic effects may include gastrointestinal disorders, nervous disorders, tremor, confusion, skin eruptions, oliguria, jaundice, and liver damage (NIOSH, 1997 Patnaik, 1992). 

Magnesium bromide occurs in sea water, surface and subterranean brines, and salt deposits. It is an electrolyte component in certain dry cells. In medicine, it is a sedative and anticonvulsant for treatment of nervous disorder. It also is used in organic synthesis forming several addition compounds. 

Nauclea rhynchophylla Miq. N. sinensis Oliv. Gou Teng (stem, spine) Rhynchophylline, isorhynchophylline.49-72 Lower blood pressure, paralyze sympathetic nerve ending, sedative, antispasmodic in infantile nervous disorders. 

N.A. Valeriana officinalis L. Essential oil, valtrate, valepotriates, bomyl esters, alkaloids, isovaltrate.99-100 Sedative for nervous disorders, antispasmodic. 

Anemia can be induced in animals on a low copper diet, such as milk, and appears 10 be due to an impaired ability of the body to absorb iron. This anemia, however, is rare, because of the widespread occurence of copper in foods. In locations, such as Australia and lire Netherlands, diseases of cattle and sheep, involving diarrhea, anemia and nervous disorders, can be traced either to a lack of copper in the diet, or to excessive amounts of molybdenum, which inhibits the storage of copper in the liver. 

A deficiency of the vitamin can result in lymphopenia, convulsions, dermatitis, irritability, and nervous disorders in humans. A defidency in monkeys may cause arteriosclerosis, while in rats, acrodynia. Research indicates that all animals require vitamin Bg, Bacteria in intestines generate some of this vitamin, but relatively little is available to humans in this form. Endogenous sources are available to plants, fungi, and some bacteria. 

Thiamin is important as a component of the coenzyme thiamin pyrophosphate (TPP) (cocarboxylase). Good sources are lucerne, grains and yeast. A deficiency is less frequently encountered than deficiencies of other vitamins, since thiamin occurs in abundance in whole grains which make up the major part of poultry diets. A diet deficient in thiamin results in nervous disorders in both young and old birds, and eventual paralysis of the peripheral nerves (polyneuritis). 

The medicine is also esteemed in some quarters for the treatment of hysteria and certain other of the nervous disorders of women. For this purpose a wineglassful of the infusion should be taken frequently. 

Many agonists or antagonists of neurotransmitter receptors are used clinically to treat nervous disorders. Some of them might also be effective medicines for skin problems. 

Celery is also used to cure a few nervous disorders (http //www.innvista.com/ health/herbs/celery.htm). An essential oil obtained from the plant has a calming effect on the central nervous system. Some of its constituents have antispasmodic, sedative and anticonvulsant actions. It has been shown to be of value in treating high blood pressure (Chavallier, 1996). Wild celery promotes restfulness and sleep in hysteria patients (Grieve, 1984) and is also used to lower blood pressure (Bown, 1995). 

The essential oil has many beneficial effects and applications in aromatherapy for skin and hair care, as an antirheumatic, antispasmodic and calmative, for complaints of the respiratory, circulatory and digestive systems and for nervous disorders. The camphor type is best suited to the musculoskeletal system, and the 1,8-cineole for pulmonary congestion and efficient functioning of the liver and kidneys, with the verbenone being a safe nonirritant essential oil for skin and hair treatments. 

Spiro, (I), and diazo derivatives, (II), prepared by Bhatti (1) and Miller (2), respectively, were effective in treating central nervous disorders characterized by an alteration in normal neurotransmitter release present in presenile and senile dementia characteristic of Alzheimer s disease. 

Mutations Carcinogenic effects Birth defects Still births Nervous disorders Liver disease Kidney disease Lung disease... 

Such terms as hepatargy , leucoencephalopathy , shunt encephalomyelopathy and encephalomyelo-pathy were put forward to classify these central nervous disorders. The term portosystemic encephalopathy... 

Arnica Arnica montana Violent gastroenteritis, nervous disorders, muscle weakness, collapse... 

Hopantenate (calcium d-(+)-4-(2, 4-dihydroxy-3, 3-dimethylbutyramido)butyrate hemihydrate), or calcium hopantenate, is a homoanalog of 1-pantothenate and has been used in Japan for the treatment of mental retardation with behavioral abnormalities. It represents one of the many attempts that have been made, so far unsuccessfully, to develop derivatives of substances belonging to the vitamin B group as agents for the treatment of brain or nervous disorders (SEDA-12, 328) (SEDA-13, 347). 

Dr. William s Pink Pills for Pale People was advertised to be a safe and effective tonic for the blood and nerves. Its label claimed that the pills treated anemic conditions, nervous disorders, and conditions caused by thin blood. 

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