Aromatic fluid extract

Aromatic fluid extract, Cascara Sagrada fluid extract)... 

Cascara sagrada, an anthraquinone glycoside mixture (325 mg p.o. h.s., 1 mL fluid extract daily or 5 mL aromatic fluid extract daily), is used in acute constipation and preparation for bowel or rectal examination. 

Crude and fluid extract, aromatic fluid extract, solid extract (bitter, bitterless, aromatic), powder extract, granular extract, and cascaroside concentrates crude, aromatic fluid extract, and bitter fluid and powder extracts are official in U.S.P. Strengths of extracts (see glossary) are expressed in weight-to-weight ratios as well as total cascaroside content. 

One example of normal-phase liquid chromatography coupled to gas chromatography is the determination of alkylated, oxygenated and nitrated polycyclic aromatic compounds (PACs) in urban air particulate extracts (97). Since such extracts are very complex, LC-GC is the best possible separation technique. A quartz microfibre filter retains the particulate material and supercritical fluid extraction (SPE) with CO2 and a toluene modifier extracts the organic components from the dust particles. The final extract is then dissolved in -hexane and analysed by NPLC. The transfer at 100 p.1 min of different fractions to the GC system by an on-column interface enabled many PACs to be detected by an ion-trap detector. A flame ionization detector (PID) and a 350 p.1 loop interface was used to quantify the identified compounds. The experimental conditions employed are shown in Table 13.2. 

M.A. Lage Yusti and J.L. Cortizo Davina, Supercritical fluid extraction and high-performance hquid chromatography-fluorescence detection method for polycyclic aromatic hydrocarbons investigation in vegetable oil. Food Cont. 16 (2005) 59-64. 

The carcinogenic aromatic amines released from azo dyes in leather were investigated by using microwave-assisted extraction (MAE) or supercritical fluid extraction (SFE) followed by RP-HPLC. The chemical structures of dyes and aromatic amines are listed in Fig. 3.69. The flow schemes for SFE and MAE are shown in Figs 3.70. and 3.71. 

Supercritical fluid extraction (EPA 3540, for total recoverable petroleum hydrocarbons EPA 3561 for polynuclear aromatic hydrocarbons) is applicable to the extraction of semivolatile constituents. Supercritical fluid extraction involves heating and pressuring a mobile phase to supercritical conditions (where the solvent has the properties of a gas and a liquid). The supercritical fluid is passed through the soil sample, and the analytes are concentrated on a sorbent or trapped cryogenically. The analytes are eluted with a solvent and analyzed using conventional techniques. Carbon dioxide is the most popular mobile phase. 

Supercritical fluid extraction of polynuclear aromatic hydrocarbons Supercritical fluid extraction of PCB and organochlorine pesticides (update IVB)... 

Oostdyk TS, Grob RL, Snyder JL, et al. 1995. Supercritical fluid extraction of primary aromatic amines from characterized soil samples comparison with sonication extraction. J Environ Sci Health A30(4) 783-816. 

Aromatic Cascara Fluid Extract /ar ous), Cascara Aromatic (Flumco)... 

OTC Aromatic Cascara Fluid extract, Cascara Sagrada, Cascara Aromatic Chemical Class Anthraquinone derivative... 

Applications for SCF Extraction Supercritical fluid extraction has been mainly used for the extraction of natural extracts for aromatic substances and essences, and for various active substances for pharmaceuticals. Alternative possibilities include... 

A comparison of extraction methods for primary aromatic amines including 1,4-phenylenediamine, 2,4-diaminotoluene, benzidine, 4,4 -methylenebis (2-chloroanilme), 3,3 -dimethylbenzidine, and 3,3 -dichlorobenzidine from solid matrices was conducted. Supercritical fluid extraction (SEE) was evaluated and compared with the classical method, sonication extraction (Oost-dyk et al., 1993). 

Polycyclic aromatic hydrocarbons (PAHs) have been extracted from contaminated land samples by supercritical fluid extraction jSFE) with both pure and modified carbon dioxide. Removing an analyte from a matrix using SFE requires knowledge about die solubility of the solute, the rate of transfer of the solute from the solid to the solvent phase, and interaction of the solvent phase with the matrix. These faclors collectively control the effectiveness of the SFF process, if not of the extraction process in general. The range of samples for which SFE has been applied continues to broaden. Applications have been in the environment, food, and polymers. 

In this paper, the supercritical fluid extraction (SFE) of organic compounds from sand spiked with 36 nitroaromatic compounds, 19 haloethers, and 42 organochlorine pesticides, and from a standard reference material certified for 13 polynuclear aromatic hydrocarbons (PAH), dibenzofuran, and pentachlorophenol was examined using a two- and a four-vessel extractor. Although the results achieved by SFE for the sand and the standard reference soil samples were very encouraging, previous data obtained in our laboratory on the standard reference soil and a few other standard reference marine sediments were less favorable. It was therefore decided that an investigation of seven variables for their influence on the analyte recoveries from the standard soil sample would be useful. Two tests were conducted in which these variables were investigated. In Test 1, the seven variables selected were pressure, temperature, moisture content, cell volume, sample size, extraction time, and modifier volume. In Test 2, the seven variables were pressure, temperature, volume of toluene added to the matrix, volume of solvent in the collection vessel,... 

The relative effects of supercitical carbon dioxide density, temperature, extraction cell dimensions (I.D. Length), and cell dead volume on the supercritical fluid extraction (SFE) recoveries of polycyclic aromatic hydrocarbons and methoxychlor from octadecyl sorbents are quantitatively compared. Recoveries correlate directly with the fluid density at constant temperature whereas, the logarithms of the recoveries correlate with the inverse of the extraction temperature at constant density. Decreasing the extraction vessels internal diameter to length ratio and the incorporation of dead volume in the extraction vessel also resulted in increases in SFE recoveries for the system studied. Gas and supercritical fluid chromatographic data proved to be useful predictors of achievable SFE recoveries, but correlations are dependent on SFE experimental variables, including the cell dimensions and dead volume. 

Hubert et al. [101] state that accelerated solvent extraction compared to alternatives such as Soxhlet extraction, steam distillation, microwave extraction, ultrasonic extraction and, in some cases, supercritical fluid extraction is an exceptionally effective extraction technique. Hubert et al. [ 101 ] studied the effect of operating variables such as choice of solvent and temperature on the solvent extraction of a range of accelerated persistent organic pollutants in soil, including chlorobenzenes, HCH isomers, DDX, polychlorobiphenyl cogeners and polycyclic aromatic hydrocarbons. Temperatures ofbetween 20 and 180 °C were studied. The optimum extraction conditions use two extraction steps at 80 and 140 °C with static cycles (extraction time 35 minutes) using toluene as a solvent and at a pressure of 15 MPa. 

Field, J.A., D.J. Miller, T.M. Field, S.B. Hawthorne, and W. Giger. 1992. Quantitative determination of sulfonated aliphatic and aromatic surfactants in sewage sludge by ion-pair/supercritical fluid extraction and derivatization gas chromatography / mass spectrometry. Anal. Chem. 64, 3161-3167. 

Bowadt, S., L. Mazeas, D.J. Miller, et al. 1997. Field-portable determination of polychlorinated biphenyls and polynuclear aromatic hydrocarbons in soil using supercritical fluid extraction. J. Chromatogr. A 785 205-217. 

Perraudin, E., H. Budzinski, and E. Villenave. 2005. Analysis of polycyclic aromatic hydrocarbons adsorbed on particles of atmospheric interest using pressurised fluid extraction. Anal. Bioanal. Chem. 383 122-131. 

Szolar, O.H., H. Rost, D. Hermann, M. Hasinger, R. Braun, and A.P. Loibner. 2004. Sequential supercritical fluid extraction (SSFE) for estimating the availability of high molecular weight polycyclic aromatic hydrocarbons in historically polluted soils. J. Environ. Qual. 33 80-88. 

Ryno, M., L. Rantanen, E. Papaioannou, A.G. Konstandopoulos, T. Koskentalo, and K. Savela. 2006. Comparison of pressurized fluid extraction, Soxhlet extraction and sonication for the determination of polycyclic aromatic hydrocarbons in urban air and diesel exhaust particulate matter. J. Environ. Monit. 8 488 193. 

With the demonstration of supercritical fluid extraction, an obvious extension would be to extract or dissolve the compounds of interest into the supercritical fluid before analysis with SFC.(6) This would be analogous to the case in HPLC, where the mobile phase solvent is commonly used for dissolving the sample. The work described here will employ a system capable of extracting materials with a supercritical fluid and introducing a known volume of this extract onto the column for analysis via SFC. Detection of the separated materials will be by on-line UV spectroscopy and infrared spectrometry. The optimized SFE/SFC system has been used to study selected nonvolatile coal-derived products. The work reported here involved the aliphatic and aromatic hydrocarbon fractions from this residuum material. Residua at several times were taken from the reactor and examined which provided some insight into the effects of catalyst decay on the products produced in a pilot plant operation. 

Liu, M.H., Kapila, S., Yanders, A.F., Clevenger, T.E., Elseewi, A.A. (1991) Role of entrainers in supercritical fluid extraction of chlorinated aromatics from soils. Chemosphere 23, 1085-1095. 

With the increasing interest in the food industry for natural sources of antioxidants for their beneficial effects on health, new potential sources have been screened among edible aromatic plants and microalgae. The cc-tocopherol content (a potent antioxidant) in parsley was reported to be 3.45mg/100g of fresh leaves obtained through supercritical fluid extraction (Diego et al., 2004). 

Supercritical fluid extraction (SFE) is a suitable process for many separation problems. The regeneration of the supercritical fluid is as important as the extraction step itself Therefore this paper presents a method to do this in a more isobaric way than the customary pressure reduction regeneration. For the example of soil remediation we have investigated the activated carbon regeneration of supercritical carbon dioxide loaded with the low-volatile polycyclic aromatic hydrocarbon (PAH) pyrene. Characteristics of supercritical fluid extraction for soil remediation are elevated temperatures and pressures up to 370 K and 300 bar. For this reason adsorption isotherms of pyrene on activated carbon up to these conditions are measured first. Subsequently this method is used to regenerate carbon dioxide in a closed solvent cycle plant with a 4 1 extractor. An economic analysis using these results indicate that the soil remediation costs will decrease for about 20 - 30 % by means of an activated carbon adsorber. 

Nonsolids Typical liquid-based oral dosage forms are elixirs, emulsions, extracts, fluid extracts, solutions, gels, syrups, spirits, tinctures, aromatic waters, and suspen-... 

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