Stand-Alone Applications

A significant difference between the MHW guidefine and other FDA and EU guidance, however, is that the Japanese guidance only applies to networked applications stand-alone applications such as PECs embedded in equipment and laboratory instrumentation are excused compliance. This position is currently being reviewed, and it is likely that those stand-alone systems that manage electronic records will also require validation. 

Sofh are applications can mainly be divided into stand-alone programs that have to be installed on a local computer, and web-based appUcation.s. Furthermore, there arc two different tcchniquc.s u.scd in web-based applications for providing the programs applets and plug-ins. Whereas plug-ins (helper applications) have to be installed to be displayed correctly in a browser, java applets are loaded by the browser on demand. The basic requirement for executing java applets is that the java Virtual Machine (jVM) must be pre-installed on the local computer, which is oltcn the case. 

The JME Editor is a Java program which allows one to draw, edit, and display molecules and reactions directly within a web page and may also be used as an application in a stand-alone mode. The editor was originally developed for use in an in-house web-based chemoinformatics system but because of many requests it was released to the public. The JME currently is probably the most popular molecule entry system written in Java. Internet sites that use the JME applet include several structure databases, property prediction services, various chemoinformatics tools (such as for generation of 3D structures or molecular orbital visualization), and interactive sites focused on chemistry education [209]. 

The JME applet is written in Java 1,0, which is available in all types and versions of web browsers, The size of the program elasses is minimal (about 40 kB), which assures fast loading. In addition, the editor may be used in a stand-alone mode as a Java application within web pages as an applet. Thanks to the independence of the Java platform, JME can run on Windows PCs, Mac/OS machines and practically all UNIX clones, including, of course, LINUX. 

Some of the stand-alone programs mentioned above have an integrated modular 3D visualization application (e.g., ChemWindow —> SymApps, ChemSketch —> ACD/3D Viewer, ChemDraw —> Chem3D). These relatively simple viewers mostly generate the 3D geometries by force-field calculations. The basic visualization and manipulation features are also provided. Therefore, the molecular models can be visualized in various display styles, colors, shades, etc. and are scalable, movable and rotatable on the screen. 

K. K. Humphreys and D. R. Brown, Ufe Cycle Cost Comparison of Advanced Storage Batteries and Duel Cells for Utility Stand-Alone and Electric Uehicle Application, Pacific Northwest Laboratory, BatteUe Memorial Institute, 1990. 

This volume contains 50 articles describing analytical techniques for the characterization of solid materials, with emphasis on surfaces, interfaces, thin films, and microanalytical approaches. It is part of the Materials Characterization Series, copublished by Butterworth-Heinemann and Manning. This volume can serve as a stand-alone reference as well as a companion to the other volumes in the Series which deal with individual materials classes. Though authored by professional characterization experts the articles are written to be easily accessible to the materials user, the process engineer, the manager, the student—in short to all those who are not (and probably don t intend to be) experts but who need to understand the potential applications of the techniques to materials problems. Too often, technique descriptions are written for the technique specialist. 

Notice that one event has units of per-demand and the others have a per-unit-time dimension. From elementary considerations, the top event can only have dimensions of per-demand (pure probability) or per-unit-time dimensions. Which dimensions they have depends on the application. If the fault tree provides a nodal probability in an event tree, it must have per-demand dimensions, if the fault tree stands alone, to give a system reliability, it must have per-unit-time dimensions. Per-unit-time dimensions can be converted to probability using the exponential model (Section 2.5.2.6). This is done by multiplying the failure rate and the "mission time" to give the argument of the exponential which if small may be... 

In filled thermometers the thermal expansion of a gas or a liquid is transmitted through a thin capillary tube to a bellows or helix, where the deformation indicates the temperature. The temperature range of filled thermometers is very wide, approximately -200 to +700 °C. They are extremely robust but are not very high in accuracy. The application is mainly for process instrumentation and as stand-alone control devices. 

An important feature of the typical system is its modularity. The most powerful EMCS installations have all three components, but often only a single module is necessai y for simple applications, such as controlling a single air-conditioning unit, or for most applications in the residential sector. Thus local and control modules arc capable of stand-alone operation without higher-level components. The functions,... 

With the availability of microcomputers, data system applications have been moved off of the shared system and onto stand alone microcomputers. Microcomputers offer the graphics capability and consistent response time desirable for data analysis prcgramming. 

Consider Equations (6-10) that represent the CVD reactor problem. This is a boundary value problem in which the dependent variables are velocities (u,V,W), temperature T, and mass fractions Y. The mathematical software is a stand-alone boundary value solver whose first application was to compute the structure of premixed flames.Subsequently, we have applied it to the simulation of well stirred reactors,and now chemical vapor deposition reactors. The user interface to the mathematical software requires that, given an estimate of the dependent variable vector, the user can return the residuals of the governing equations. That is, for arbitrary values of velocity, temperature, and mass fraction, by how much do the left hand sides of Equations (6-10) differ from zero ... 

Semiautomatic devices suited for preparative purposes are the CAMAG Linomat 5, the Desaga HPTLC applicator AS 30, and the Alltech TLC sample streaker. For all devices, the syringe has to be filled manually with sample solution and rinsed after sample application. Except for the Alltech TLC sample streaker, each of these instruments can be employed either as software-controlled or as a stand-alone device. The former is more convenient for creation, editing, and saving of the application pattern and instrument parameters. 

The chapters of this volume provide detailed reviews of the current understanding in a range of U-series isotope applications with emphasis on advances made since 1992. Although each chapter has been written to stand alone, cross referencing to other chapters is included where appropriate. 

Beginning with SAS 9.1, the SAS XML Mapper (previously known as Atlas) is a SAS stand-alone Java application supplied as part of Base SAS. The SAS XML Mapper is a graphical user interface assistant for building SAS XML Map files. Here is a display that shows the previous example s XML Map file being built from within the XML Mapper application ... 

Aero-derivative gas turbines are typically used for offshore applications where weight and efficiency are a premium, to drive compressors for natural gas pipelines, and stand-alone power generation applications for peak periods of high power demand. For stand-alone applications, gas turbine efficiency becomes a critical issue. However, if heat is to be recovered from the gas turbine exhaust, the efficiency becomes less important as the waste heat is utilized. 

As mentioned previously, additive treatments involve the application of a polymer to the fibre. This is usually prepared before application and contains reactive groups. However, it is also possible to form the polymer in situ within the fibres. The traditional approach is to apply the polymer after a subtractive oxidation treatment but environmental concern over A OX problems is increasing demand for additive treatments that can stand alone. There is no denying that the oxidative step can facilitate subsequent treatment with a polymer, since the scission of cystine disulphide bonds to yield cysteic acid residues provides useful reactive sites for crosslinking or anchoring the polymer. 

Apart from these findings, the limited application of ZnCl2 (cyclopropanation of some cyclic 1,3-dienes, isoprene and ethyl vinyl ether 4S-49)) and copper(II) acetyl-acetonate (cyclopropanation of enamines 50)) still stand alone. 

For each wind energy system category, there is a particular approach of how to apply an electrolyzing hydrogen production unit. The most common application studied currently is the stand-alone wind energy system combined with an electrolyzer. The latter is connected in the place of the battery cluster. The electrolyzer unit can be either a PEM or an alkaline type where there is a constant feed with water. The produced hydrogen is usually stored in a tank at the output pressure of the electrolyzer or compressed at a higher... 

Optimizers for Stand-Alone Operation or Embedded Applications... 

Optimizers for Stand-Alone Operation or Embedded Applications / 8.9.2 Spreadsheet Optimizers / 8.9.3 Algebraic Modeling Systems... 

For example, an application that reads stock figures from a newsfeed can be wired up to a spreadsheet this component does some calculations and passes the results to a database, from which a Web server extracts information on demand. Each of these components may be a stand-alone application, perhaps even with its own user interface, but is provided with a way to interact with other software. 

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