Analytical data reporting

The accuracy of many analytical data reports is a mirage because unwitting negligence and false cost consciousness have ensured that a sample . .. taken with cursory swiftness has been examined with costly precision. Kaye, Illinois Institute of Technology (1967) ... 

In contrast to the previous work (192) Holah and Murphy report that all attempts to make complexes of the type Fe(R2Dtc)J, in various solvents and employing a multitude of synthetic procedures, failed (330). An examination of the analytical data reported for the Fe(R2Dtc)J complexes (192) leaves some doubt as to their analytical purity. However, the reported equilibria (Eq. 26) may account for difficulties in synthesizing and purifying these complexes. 

After characterization of the physisorption, we wish to get information on the ultimate chemical structure of the coating. Spectroscopic analysis of the modified substrate is used to complement the indirect analytical data, reported above. Further elucidation of the chemical bonding of the silanes to the surface is obtained from 29Si CP MAS NMR. With this technique, the formation of siloxane bonds with the surface can be modelled. 

In 1954, Kosak (2170) pnblished a list of components reported to be present in tobacco smoke. His list is shown in Table 111-1. The aldehydes listed included formaldehyde, acetaldehyde, acrolein (2-propenal), butyraldehyde (bntanal), benzaldehyde, and 2-fnraldehyde. In several instances, Kosak qnestioned whether the analytical data reported were snffi-cient to define nneqnivocally the identity of the smoke component. The ketones listed by Kosak included 3-pentanone (diethyl ketone), 4-heptanone (di-n-propyl ketone), 17-tritri-acontanone (dipalmityl ketone), 2,3-butanedione (biacetyl), and higher ketones. 

Participating laboratories should maintain these documents QA/QC program plans QA/QC status reports CTQ proficiency program reports and, analytical data reports. The information that should be included in these reports is summarized in Table 2 a copy of each report should be sent to the responsible physician. 

Analytical Data Report For all reports of data results Date the sample was received Date the sanple was analyzed Appropriate chain-of-custody information Types of analyses performed Results of the requested analyses and Copy of the most current proficiency report. 

Analytical data reports should be submitted to responsible physicians directly. For each sample, report the following information The date the sample was received the date the sample was analyzed appropriate chain-of-custody information the type(s) of analyses performed and, the results of the analyses. This information should be reported on a form similar to the form provided an appropriate form. The most recent proficiency program report should accompany the analytical data reports (as an attachment). 

Sample preparation is the acmal generation, synthesis, or preparation of samples for calibration and monitoring. It should be achieved in such a way that the sample presented for analysis has not been changed from its original state. Sample preparation without causing changes in moisture content may not be possible. Precautions should be taken to determine the moisture content before and after preparation, and the analytical data reported on the basis of the original moisture content, except in cases where data have to be reported on a constant moisture basis. 

The EPA publishes Series Methods that describe the exact procedures to be followed with respect to sample receipt and handling, analytical methods, data reporting, and document control. These guidelines must be followed closely to ensure accuracy, reproducibility, and reliability within and among the contract laboratories. 

LynestrenoL Lynestrenol (73) has been used in oral contraceptives and to treat menstrual disorders. It is converted in vivo to its active metabohte norethindrone (102,103). It can be recrystallized from methanol, and is soluble in ethanol, ether, chloroform, and acetone, and insoluble in water (102). The crystal stmcture (104) and other spectral and analytical data have been reported for lynestrenol (62). 

A laboratory information management system (LIMS) is a computer or computer network used to automate the acquisition and management of raw analytical data. In its simplest form, it tracks samples and test results through analytical laboratories and provides summaries of the status of these samples and tests. In its most advanced form, the system is interfaced to the laboratory s instmmentation and communication network to allow automation of data gathering, compilation, and reporting. 

Dietary Copper. Analytical data indicate that many diets contain less than the RDA for copper (109). Excessive copper has been reported to be fatal for oral dose levels of copper sulfate of 200 mg/kg body weight for a child and 50 mg/kg for adults. 

Minerals. Nuts are considered to be a good source of minerals essential for nutrition, supplying elements of copper, manganese, iron, and sulfur (see Mineral nutrients). The values for the mineral constituents of many nuts shown in Table 2 are averages of available analytical data. Values for the mineral content of the peanut kernel (28) and ash constituents in the macadamia kernel (29) and cashew (26) have also been reported. Chufa nuts have a high sihcon content. 

Documentation of the system design and operating data, analytical assumptions and constraints used in the analysis in a notebook becomes part of the QA record. However, it is useful to have documents analyses and records as computer files for handling the voluminous data reporting and presenting the results of the work. It provides. 

Sawicki (13) used solid-surface fluorescence techniques extensively in the 1960 s for air pollution research. In 1967, Roth (14) reported the RTF of several pharmaceuticals adsorbed on filter paper. Schulman and Walling (15) showed that several organic compounds gave RTF when adsorbed on filter paper. Faynter et al. (16) reported the first detailed analytical data for RTF and gave limits of detection, linear dynamic ranges, and reproducibilities for the compounds. 

An alternative for evaluating accuracy is spiking known amounts of standards to a food, as reported in several papers,although percent recoveries of spikes do not truly address the influence of the food matrix complexity on the extraction efficiency. Data evaluation procedures were developed as a manual system to assess the quality of analytical data for carotenoids in foods. ... 

Preparation of Block Copolymers. Poly(styrene-b-methyl methacrylate) and poly(styrene-b-t-butyl methacrylate) were prepared by procedures similar to those reported for poly(styrene-b-methyl methacrylate (12,13). Poly(methyl methacrylate-b-t-butyl methacrylate) was synthesized by adaptation of the method published (14) for syndiotactic poly(methyl methacrylate) polymerization of methyl methacrylate was initiated with fluorenyllithium, and prior to termination, t-butyl methacrylate was added to give the block copolymer. Pertinent analytical data are as follows. 

Begun in 1944 with DDT and in 1947 with parathion, the present report includes analytical data secured from certain chemical, mechanical, and solvent actions on apples, pears, lemons, and oranges. In the absence of established tolerances for these two insecticidal materials, it is hardly possible to interpret the significance of many of these data with respect to consumer hazard. 

Hufford et al [57] used proton and 13C NMR spectrometric data to establish the novel sulfur-containing microbial metabolite of primaquine. Microbial metabolic studies of primaquine using Streptomyces roseochromogenus produced an A-acety-lated metabolite and a methylene-linked dimeric product, both of which have been previously reported, and a novel sulfur-containing microbial metabolite. The structure of the metabolite as an S-linked dimer was proposed on the basis of spectral and chemical data. The molecular formula C34H44N604S was established from field-desorption mass spectroscopy and analytical data. The 1H- and 13C NMR spectra data established that the novel metabolite was a symmetrical substituted dimer of primaquine A-acetate with a sulfur atom linking the two units at carbon 5. The metabolite is a mixture of stereoisomers, which can equilibrate in solution. This observation was confirmed by microbial synthesis of the metabolite from optically active primaquine. 

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