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Alkyl halides reaction

Alkyl halides, reaction of sugar phosphorodiamide and phosphonamide derivatives with 178... [Pg.263]

Electrogenerated monovalent Co complexes of the well-known open chain N202 Schiff base ligands salen (8), salphen (9), and their substituted derivatives undergo oxidative additions with alkyl halides. Reactions of the complex with substrates within the series RBr (R = Pr, Bu, t-Bu) proceed at different rates. The reaction occurs by an inner-sphere alkyl-bridged electron transfer, with a Co1- R+- X-transition state, which is sensitive to distortions of the complex in different configurations.124... [Pg.11]

Acid chloride Alkyl halide Reaction conditions % yield... [Pg.94]

Generally, smaller particles are obtained with polar, more highly solvating solvents. However, these solvents do not necessarily yield the most active metal slurries. The reactivities vary, and the metal slurries can be fine tuned somewhat for use in specific types of reactions. For example, nickel particles from pentane are very active as hydrogenation catalysts, whereas nickel particles from THF are not active as hydrogenation catalysts but are very active in alkyl halide reactions. [Pg.79]

The first reaction provides a route for the reduction of alkyl halides since the carbo-cation (isopropyl, in Rl) may be prepared from action of AICI3 on the corresponding alkyl halide. Reactions of the type Rl are also important in the process, catalytic cracking, in the manufacture of gasoline. They have also been studied in mass spectro-metric experiments [235]. Reaction R2 is one route to the preparation of carbocations under stable ion conditions. Reaction R3 is employed in the laboratory synthesis of the tropylium cation. Reaction R4, the (crossed) Cannizzaro reaction, is unusual in that it takes place under strongly basic conditions. The oxy dianion is an intermediate in the reaction of concentrated hydroxide with the aldehyde, R HO. None of R1, R2, or R3 may have hydrogen atoms a to the carbonyl groups. Formaldehyde (R1 = H) is readily... [Pg.146]

Several useful variations of the tetracarbonyliron dianion-alkyl halide reactions are known. These employ the iron complex stoichiometrically, however. Since the dianion is much more nucleophilic than the alkyliron monoanion, the reaction can easily be stopped at the monoalkylated stage. Carbonylation or addition of another good ligand such as triphenylphos-phine to the monoalkylated complexes produces monoacyliron anions. Pro-... [Pg.332]

The alternative disconnection, between the alkyl group and the heteroatom 21, is also acceptable but it would require an Sn2 reaction between the anion of the acid 22 and an alkyl halide. Reactions at carbonyl groups are much more reliable than Sn2 reactions and are usually preferred. Only if the Sn2 reaction is exceptionally good, as it would be to make the ester 23, is this route preferred. [Pg.25]

Alkyl halides, reaction with, A-4-thiazoline-2-thiones anion, 392, 396 4-Alkylidene-A-2-thiazoline-5-one, 427 Friedel-Crafts reaction on, 428 Grignard reaction on, 429... [Pg.288]

The addition of carbon electrophiles is not limited to simple alkyl halides. Reaction of tropylium hexafluorophosphate with 63, for example,... [Pg.44]

Meerwein and co-workers (16) reported long ago that simple anions such as Cl" lead to unstable complexes that decompose to give the ether and the alkyl halide (Reaction 1)... [Pg.353]

In early work, certain seven-membered and larger cyclic arsines were characterized by preparation and isolation of their arsonium salts by quaternization with alkyl halides. Reaction of more elaborate seven-membered cyclic arsines with activated alkyl bromide is shown in Equation (1). The C2-symmetric chiral tertiary arsine 61 reacts with methyl bromoacetate in a pressure tube under microwave irradiation to give the arsonium salt 62 in 71%. The latter was employed in the enantioselective olefination of 4-substituted cyclohexanes via the corresponding stabilized ylide <2002TA2187>. [Pg.962]

The reaction between powdered tin, hydrogen chloride, and an a,/3-nnsatnrated carbonyl or cyano compound produces diorganotin dichloride species (equation 3). Tin(II) halides react similarly to give X3SnCH2CH2Y (equation 4). Direct reactions of tin(II) halides with alkyl halides to give aUcyltin trihalides require the same catalysts as used for tin/alkyl halide reactions trialkylstibines are particularly effective catalysts (equation 5). [Pg.4874]

Hydroalumination of alkenes. Hydroalumination of alkynes is a well-known reaction, but hydroalumination of alkenes has been achieved only recently under catalysis by TiCU or ZrCU, (8, 288). As expected hydroalumination affords a convenient, high-yield route to primary alkanes (by hydrolysis), terminal primary alcohols (by oxygenation), and primary alkyl halides (reaction with halogens, N-halosuccinimides, or CuXa). ... [Pg.143]

Alkyl halide reactions with NaP(OH)j yield alkylphosphinites which upon heating disproportionate ... [Pg.61]

Similar information is available for other bases. Lithium phenoxide (LiOPh) is a tetramer in THF. Lithium 3,5-dimethylphenoxide is a tetramer in ether, but addition of HMPA leads to dissociation to a monomer. Enolate anions are nucleophiles in reactions with alkyl halides (reaction 10-68), with aldehydes and ketones (reactions 16-34, 16-36) and with acid derivatives (reaction 16-85). Enolate anions are also bases, reacting with water, alcohols and other protic solvents, and even the carbonyl precursor to the enolate anion. Enolate anions exist as aggregates, and the effect of solvent on aggregation and reactivity of lithium enolate anions has been studied. The influence of alkyl substitution on the energetics of enolate anions has been studied. ... [Pg.390]

A139. J. K. Kochi, ed., Free Radicals. Wiley (Interscience), New York, 1973. Vol. 1, 683 pp. Vol. 2, 852 pp. Volume 1, Chapter 6 contains a useful summary of organo-metallie-alkyl halide reactions, mainly involving RLi species. Chapter 10 by A. G. Davies and B. P. Roberts is entitled Bimolecular Homolytic Substitution at Metal Atoms." Volume 2 contains a chapter of 67 pp. (266) by H. Sakurai on group IVB radicals. [Pg.464]

Alkyl Halides. Reaction with Co (CN) 5. Manya-bondedorgano-pentacyanocobaltate(III) complexes have been prepared recently by the reaction of organic halides with pentacyanocobaltate(II) (i3, 14, 21, 22) (Reaction 5). The second-order kinetics observed for this reaction (14)... [Pg.216]

Lead slurries prepared by metal vaporization procedures (in THF or diglyme) react with CH3I, although only a small amount of (CH3)3PbI is obtained. Direct Pb-alkyl halide reactions require Pb-Na alloy . [Pg.358]


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Acetylide anions reactions with alkyl halides

Alcohols reaction with alkyl halides

Alkenes reaction with alkyl halides

Alkyl groups alcohol reactions with hydrogen halides

Alkyl halide coupling reactions

Alkyl halide elimination reactions

Alkyl halide reaction with Gilman reagents

Alkyl halide reaction with carboxylate ions

Alkyl halide reaction with phthalimide ion

Alkyl halide reaction with thiourea

Alkyl halide reaction with tributyltin hydride

Alkyl halide substitution reactions

Alkyl halides Compounds with halogen elimination reaction

Alkyl halides Direct Process Reaction

Alkyl halides Friedel-Crafts reactions

Alkyl halides Grignard reaction

Alkyl halides Kumada cross-coupling reactions

Alkyl halides SN2 reactions

Alkyl halides alcohol reactions with hydrogen

Alkyl halides cobalt-catalyzed Heck reactions

Alkyl halides from addition reactions

Alkyl halides gas-phase reactions

Alkyl halides hydrolysis reactions

Alkyl halides nucleophilic substitution reactions

Alkyl halides reaction with acetylides

Alkyl halides reaction with water

Alkyl halides reactions and characterisation

Alkyl halides reactions with ambident

Alkyl halides reactions with organocopper reagents

Alkyl halides reactions with sulfur

Alkyl halides synthetic reactions with

Alkyl halides with chlorine, reaction

Alkyl halides with nitrogen, reaction

Alkyl halides, 787 dehydrogenation reactions

Alkyl halides, alkylation reactions

Alkyl halides, alkylation reactions

Alkyl halides, displacement reactions

Alkyl halides, from alcohols reactions

Alkyl halides, from nucleophilic substitution reactions

Alkyl halides, reaction with aluminum

Alkyl halides, reaction with indole Grignard

Alkyl halides, reaction with indole Grignard reagents

Alkyl halides, reactions with arene

Alkyl halides, reactions with arene Table

Alkyl halides, reactions with trimethylsilyl

Alkyl halides—continued reactions

Alkylation reactions phenols with alkyl halides

Alkyne anions reaction with alkyl halides

Ammonia reaction with alkyl halides

Aniline derivatives alkyl halide reactions

Antimony, reaction with alkyl halides

Azidation reactions alkyl halides

Azide ion reaction with alkyl halides

Benzylic reaction with alkyl halides

Butyrolactones, reactions with alkyl halide

By Reaction with Alkyl Halides

Carbocation alkyl halide reaction with Lewis

Carbocations as intermediates in reactions of alkyl halides

Catalytic asymmetric cross-coupling reactions with secondary alkyl halides

Catalytic reactions alkyl halides

Copper reactions with alkyl halides

Cross-coupling reactions alkyl halides

Cross-coupling reactions alkyl halides with Grignard reagents

Cross-coupling reactions with alkyl halides

Cyanamide reaction with alkyl halides

Cyanides, metal, reaction with alkyl halides

Cyanocuprates, reactions with alkyl halides

Dithiane anions reaction with alkyl halides

Elimination Reactions by Sml2 Reduction of Alkyl Halides

Elimination Reactions of Alkyl Halides Zaitsevs Rule

Elimination Reactions of Alkyl and Alkenyl Halides

Elimination reactions of alkyl halides

Enolate anions reaction with alkyl halides

Enolate anions, dianions reaction with alkyl halides

Enolate anions, esters, reaction with alkyl halides

Enolates reaction with alkyl halide

Ethers reaction with alkyl halides

Exchange reactions alkyl-halide

Formylation reactions alkyl halides

Friedel-Crafts reaction with alkyl halides

Gilman cuprates, reactions with alkyl halides

Grignard reaction: alkylation with mercury halides

Grignard reagents coupling reactions with alkyl halides

Grignard reagents, reaction with alkyl halides

Halide ions reaction with alkyl halides

Halides coupling reactions with primary alkyl Grignard

Halides, alkyl intramolecular reactions with

Halides, alkyl reaction with NaSH

Halides, alkyl reaction with acetoacetic ester anions

Halides, alkyl reaction with acid salts

Halides, alkyl reaction with alkoxides

Halides, alkyl reaction with alkynes

Halides, alkyl reaction with aluminum hydride reagents

Halides, alkyl reaction with amide anions

Halides, alkyl reaction with amines

Halides, alkyl reaction with aromatic compounds

Halides, alkyl reaction with carbanions

Halides, alkyl reaction with carboxylic acid salts

Halides, alkyl reaction with cyanohydrins

Halides, alkyl reaction with enamines

Halides, alkyl reaction with hexamethylenetetramine

Halides, alkyl reaction with hydrazone anions

Halides, alkyl reaction with hydrogen sulfide

Halides, alkyl reaction with hydroxide

Halides, alkyl reaction with ketone enolate anions

Halides, alkyl reaction with ketones

Halides, alkyl reaction with lithium

Halides, alkyl reaction with magnesium

Halides, alkyl reaction with malonate anions

Halides, alkyl reaction with metals

Halides, alkyl, base induced reactions

Halides, alkyl, reaction with Bu3SnH

Halides, alkyl, reaction with Lewis acids

Halides, alkyl, reaction with Subject

Halides, alkyl, reaction with acid dianions

Halides, alkyl, reaction with amino ester enolates

Halides, alkyl, reaction with amino-alcohols

Halides, alkyl, reaction with azide

Halides, alkyl, reaction with cuprates

Halides, alkyl, reaction with cyanide

Halides, alkyl, reaction with cyanoborohydride

Halides, alkyl, reaction with dimethyl sulfide

Halides, alkyl, reaction with ester dianions

Halides, alkyl, reaction with ester enolates

Halides, alkyl, reaction with ferrate

Halides, alkyl, reaction with imides

Halides, alkyl, reaction with lactone enolates

Halides, alkyl, reaction with malonate enolates

Halides, alkyl, reaction with nitrile enolates

Halides, alkyl, reaction with nitro compounds

Halides, alkyl, reaction with organocuprates

Halides, alkyl, reaction with organolithium reagents

Halides, alkyl, reaction with phthalimide

Halides, alkyl, reaction with succinimide

Halides, alkyl, reaction with sulfides

Heck-type Reaction of Alkyl Halides with Styrenes

Hydroxide, potassium reaction with alkyl halides

Hydroxy halides, alkylation reaction, with alkali

I Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations

Indole compounds alkyl halide reactions

Intermolecular reactions alkyl halides

Iodide, potassium reaction rates with alkyl halides

Iodide, sodium reaction with alkyl halides

Iron, reaction with alkyl halides

Key Concepts—Alkyl Halides and Elimination Reactions

Kumada cross-coupling reactions, palladium alkyl halides

Lewis acid alkyl halide reactions

LiAlH4, reaction with alkyl halides

Lithium, vinylalkylation reaction with alkyl halides

Magnesium reaction of with alkyl and aryl halide

Magnesium reaction with alkyl halides, mechanism

Magnesium, reaction with alkyl halides form Grignard reagents

Magnesium-alkyl halide reaction

Metal phosphites reaction with alkyl halides

Nickel catalysts alkyl halide reactions

Nitrite, sodium reaction with alkyl halides

Nucleophiles alkyl halide substitution reactions

Nucleophilic substitution reactions of alkyl halides

Organocopper compounds, reactions with alkyl halides

Organometallic compounds reaction with alkyl halides

Organozinc reagents cross-coupling reactions with alkyl halides

Oxazine anions, reaction with alkyl halides

Oxazine anions, reaction with alkyl halides alkylation

Palladium, phenylbis catalysis arylmagnesium halide reaction with alkyl halides

Phosphines alkyl halide reactions

Phosphines reaction with alkyl halides

Phosphines reaction with alkyl halides, kinetics

Phosphoramidic acid, N- diethyl ester reaction with alkyl halides

Phosphorane, iminovinylidenetriphenylphosphonium ylide synthesis reactions with alkyl halides

Phosphorus, reaction with alkyl halides

Primary alkyl coupling reactions with alkenyl halides

Primary alkyl coupling reactions with aromatic halides

Primary alkyl halides reactions

Primary alkyl reactions with alkenyl halides

REACTIONS OF ALKYL HALIDES

Radicals, coupling reactions with alkyl halides

Reaction CXIX.—Action of Silver Nitrite on Alkyl Halides

Reaction CXXV.—Action of Alkyl Halides on Phthalimide (Potassium Salt)

Reaction XIV.—(a) Action of Magnesium Alkyl or Aryl Halide on Aldehydes and Ketones (Grignard)

Reaction of Alkyl, Alkenyl, and Aryl Halides with Metals

Reaction of Amines with Alkyl Halides

Reaction of Lithiated Bis(methylthio)methane with Alkyl Halides

Reaction of alkyl halides with sulfites and sulfinic acids

Reaction of stabilized carbanions (enolates) with alkyl halides (enolate alkylation)

Reaction with Alkyl and Aryl Halides

Reaction with alkyl halides

Reaction with alkyl halides to form

Reactions alkyl halides, kinetics

Reactions of Alkyl Halides Grignard Reagents

Reactions of Alkyl Halides Nucleophilic Substitutions and Eliminations

Reactions of Alkyl Halides Substitution and Elimination

Reactions of Alkyl Halides The Substitution Reaction

Reactions with Simple Alkyl Halides

Reactions with activated alkyl halides

Reactivity, alkyl halides with reactions

Rearrangement Reactions of Alkyl and Alkenyl Halides

Reduction reaction kinetics alkyl halides

Reduction reactions alkyl halides

Secondary alkyl halides acetylide anion reactions with

Secondary alkyl halides reactions

Silver cyanide, reaction with alkyl halides in synthesis of isocyanides

Silver nitrate, reaction with alkyl halides

Silver reaction with alkyl halides

Sn2 reaction of alkyl halides

Sn2 substitution reactions conversion of alcohols to alkyl halides

SnI reaction of alkyl halides

Sodium acetylide reaction with, alkyl halides

Sodium reaction with alkyl halides

Sodium sulfide, reaction with alkyl halides

Stereoselective reactions dehydrohalogenation of alkyl halides

Substitution reactions of alkyl halides

Sulfones anions, reaction with alkyl halides

Tertiary alkyl coupling reactions with alkenyl halides

Tetracarbonylferrate reaction with alkyl halides

The Reaction with Alkyl Halides

Thiocyanates reaction with alkyl halides

Thioethers reaction with alkyl halides

Thiol reaction with alkyl halides

Thiolate ions reaction with alkyl halides

Thiols reaction with alkyl halides

Thioureas reaction with alkyl halides

Trialkyltin hydride-alkyl halide reactions

Triphenylphosphine reaction with alkyl halides

Water alkyl halide-metal reaction

Zinc, reaction with alkyl halides

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