Vaginal disorder

Oral treatment offers the advantage of bringing all the lesions at all sites under control, in addition to the absence of unpleasant cosmetic effects. In certain cases, it may be preferable to use oral treatment for C. albicans vaginitis and for extensive and persistent pityriasis versicolor, a skin disorder caused by Pityrosporum orbiculare. In the case of onychomycosis, a combination treatment, topical plus systemic, is required. It is preferable to use oral treatment for deep and systemic mycoses, though intravenous or intrathecal treatment is sometimes required. 

Reproductive disorders Endometrial disorder Leukorrhea Uterine disorder Uterovaginal prolapse Vaginal discomfort Urinary system disorders Micturition frequency Urinary incontinence Gastrointestinal disorders Abdominal pain Constipation... 

Significant adverse reactions include edema vaginitis nervousness emotional lability hepatic dysfunction elevated blood pressure pelvic pain carpal tunnel syndrome sleep disorders fatigue tremor visual disturbances anxiety depression gastroenteritis. 

Miscellaneous Edema (flurbiprofen, naproxen, meloxicam) thirst pyrexia (fever and chills) sweating breast changes gynecomastia muscle cramps facial edema menstrual disorders impotence vaginal bleeding influenza-like disease/symptoms (meloxicam). 

Miscellaneous Anxiety depression dizziness headache rash abdominal pain/discomfort gingival disorder infectious diarrhea nausea rectal pain/discomfort tooth disorder vomiting arthritis back pain myalgia lower extremity pain menstrual irregularity vaginitis influenza upper/lower respiratory tract infection fatigue otitis sleep disorder urinary tract infection. 

Contraindications Abnormal vaginal bleeding, active arterial thrombosis, blood dys-crasias, estrogen-dependent cancer, known or suspected breast cancer, thrombophlebitis or thromboembolic disorders, thyroid dysfunction... 

Contraindications Breast cancer, cerebral apoplexy or history of these conditions, severe liver dysfunction, thromboembolic disorders, thrombophlebitis, undiagnosed vaginal bleeding, genital malignancy... 

Contraindications Allergy to peanut oil (oral), breast cancer, history of active cerebral apoplexy, thromboembolic disorders or thrombophlebitis, severe hepatic dysfunction, undiagnosed vaginal bleeding... 

For the treatment of panic disorder, the starting adult dose is 0.25 mg twice a day, which may be increased by one mg daily after three days. Clonazepam s safety and effectiveness has not been determined for individuals under the age of 18. Side effects in the treatment of panic disorders are similar to many of the benzodiazepines, and include allergic reaction, inflamed sinuses or nasal passages, flu, menstrual problems, respiratory infection, speech problems, and vaginal inflammation. 

The activity of the enzyme in cancer tissue has been measured,11 and changes in its activity in vaginal fluid have been examined as a possible diagnostic aid in cervical cancer.29 Low levels in human tissues have been associated with a storage disorder resembling Hurler s syndrome.18,183... 

Oxytocin is used to induce labor for conditions requiring early vaginal delivery such as Rh problems, maternal diabetes, preeclampsia, or ruptured membranes. It is also used to augment abnormal labor that is protracted or displays an arrest disorder. Oxytocin has several uses in the immediate postpartum period, including the control of uterine hemorrhage after vaginal or cesarean delivery. It is sometimes used during second-trimester abortions. 

These drugs are contraindicated in patients with thrombophlebitis, thromboembolic phenomena, and cardiovascular and cerebrovascular disorders or a past history of these conditions. They should not be used to treat vaginal bleeding when the cause is unknown. They should be avoided in patients with known or suspected tumors of the breast or other estrogen-dependent neoplasms. Since these preparations have caused aggravation of preexisting disorders, they should be avoided or used with caution in patients with liver disease, asthma, eczema, migraine, diabetes, hypertension, optic neuritis, retrobulbar neuritis, or convulsive disorders. 

A vaginal suppository based on bromocriptine was employed for the therapy of hyperprolactinemia [32]. The rationale of the local vaginal delivery of bromocriptine lies in the noteworthy side effects consequent to oral therapy gastrointestinal disorders, extensive hepatic degradation, and hypotension. The pessary based on bromocriptine proved to be effective in lowering serum prolactin to normal levels after 20 days of local therapy the treatment was well tolerated by the majority of the patients and a minimal vaginal irritation was observed. 

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