Disorders gastrointestinal

On completion of this case study, you will be able to  

Clinical Physiology and Pharmacology Farideh Javid and Janice McCurrie 2008 John Wiley Sons, Ltd 

Q3 Outline the factors in the history which may be contributing to this patient s constipation. 

Q4 Which types of drug may cause constipation as a side effect  

Q6 To which category of drugs does lactulose belong Comment on its mechanism of action and the recommended dose. 

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Indications are mycoses of the skin, hair, and nails due to species of Trichophyton Tpidermophyton floccosum and Microsporum. Yeasts and bacteria are not sensitive. Griseofulvin has a very weak effect against Side effects may include headaches and gastrointestinal disorders, but they are usually only... 

Bismuth compounds were once employed for the treatment of amoebic dysentery, certain skin diseases, and several spirochetal diseases besides syphilis, but these substances are now seldom considered the dmgs of choice. Various insoluble preparations of bismuth, especially the subcarbonate, subnitrate, subgaHate, subcitrate, and subsahcylate, are stiU employed for the treatment of ulcers and other gastrointestinal disorders, even though use for these purposes is often supported largely by tradition. With a few possible exceptions, it is now difficult to justify the presence of bismuth compounds in a modem therapeutic armamentarium. A review of the biological activity of organobismuth compounds has been pubHshed (179). 

Irritable bowel syndrome (DBS) is an exceedingly common condition in all societies, characterized by abdominal discomfort or pain in association with altered bowel habit or incomplete stool evacuation, bloating and constipation or diarrhoea, easily go undetected and do not show up with common tests such as blood tests or x-rays. The estimated prevalence in the community is about 10%. Irritable bowel syndrome and its variants, collectively called functional gastrointestinal disorders, constitute 40-50% of all the patients seen by gastroenterologists in Western countries. 

Gastrointestinal disorders (e.g. dyspepsia), gastrointestinal erosion with bleeding, ulceration and perforation... 

It is important to use these drag with caution in patients with a history of gastrointestinal disorders, renal disease, or liver impairment. The neuromuscular blocking action of die lincosamides poses a danger to patients widi myasthenia gravis (an autoimmune disease manifested by extreme weakness and exhaustion of die muscles). 

These drug are used cautiously in patients with gastrointestinal disorders, renal function impairment and those who are pregnant or lactating. 

List the types of drugs prescribed or recommended for gastrointestinal disorders. 

SUM MARY DRUG TABLE DRUGS USED IN THE MANAGEMENT OF GASTROINTESTINAL DISORDERS... 

There are various types of laxatives (see the Summary Drug Table Dm Used in the Management of Gastrointestinal Disorders). The action of each laxative is somewhat different, yet they produce the same result—the relief of constipation (Display 48-1). 

Use treatment of gastrointestinal disorders (ulcerative colitis, Crohn s disease)... 

Anticholinergics used in gastrointestinal disorders Over-the-counter antiasthma drugs Note. Cannabis not included here. 

FLOCK M H, HONG-cuRTiss J (2002) Probiotics and Functional Foods in Gastrointestinal Disorders. Curr Treat Options Gastroenterol. 5 311-21. 

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