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Ubiquitin, ubiquitination

A number of different proteolytic systems are thought to be responsible for the degradation of soluble proteins in the cytoplasm of eukaryotic cells. One of the best understood is that which involves ATP and the protein ubiquitin. Ubiquitin is a small protein of only 76 residues. It occurs universally in eukaryotic cells and is highly conserved in sequence only three residues distinguish the ubiquitin in yeast and humans. The covalent attachment of ubiquitin to proteins is thought to tag them for subsequent hydrolysis by cellular proteases. [Pg.763]

Ubiquitin Ubiquitin is a small intracellular protein that serves as a marker for protein... [Pg.240]

Ubiquitination Ubiquitin Cyclin Control of cell cycle... [Pg.284]

Blocking sites of ubiquitination (ubiquitination is a signal for protein turnover - see here), and... [Pg.904]

El Oualid F, Merkx R, Ekkebus R, Hameed DS, Smit JJ, de Jong A, Hilkmann H, Sixma TK, Ovaa H (2010) Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin. Angew Chem Int Ed 49 10149-10153... [Pg.85]

The Nobel Prize in Chemistry 2004 was awarded to A. Ciechanover, A. Hershko, and I. Rose for their work on protein degradation by ubiquitin (ubiquitination of proteins). For additional information, see the review of the first two winners (Hershko and Ciechanover, 1998) and the Nobel Conference on the ubiquitin system (Rose, 2005). Enantiomer (+)-hexylitaconic acid was isolated for the first time in the terrestrial species Aspergillus niger, it is a regulator of plant growth (Isogai et al, 1984). [Pg.540]


See other pages where Ubiquitin, ubiquitination is mentioned: [Pg.1263]    [Pg.242]    [Pg.722]    [Pg.101]    [Pg.525]    [Pg.479]    [Pg.1263]    [Pg.525]    [Pg.150]    [Pg.659]    [Pg.89]    [Pg.276]    [Pg.288]    [Pg.313]    [Pg.836]    [Pg.107]    [Pg.72]   
See also in sourсe #XX -- [ Pg.186 , Pg.187 , Pg.189 ]




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Amino acid degradation ubiquitination

Bioinformatics of Ubiquitin Domains and Their Binding Partners

COP9 ubiquitin ligases

Components of the Ubiquitin System

Cyclin, ubiquitination

Cytosolic ubiquitin protein

Cytosolic ubiquitin protein degradation

E2 Enzymes Dedicated to Ubiquitin-like Proteins (UbLs)

E2 ubiquitin conjugating enzyme

E3 ubiquitin ligase

Enzymes with Additional Ubiquitin-binding Sites

Folding ubiquitin

Functional Diversity of Ubiquitin-conjugating Enzymes

Histone H2A, ubiquitination

Histone modifications ubiquitination

Histone ubiquitination

Human ubiquitin

Isopeptide linkage to ubiquitin

Major histocompatibility ubiquitinated

Molecular dynamics simulation ubiquitin

Mono-ubiquitin

Mono-ubiquitin adducts

Mono-ubiquitination

N-terminal Ubiquitination No Longer Such a Rare Modification

Other Ubiquitin-binding Domains

Phosphoprotein-ubiquitin ligase

Phosphoprotein-ubiquitin ligase complexes

Poly-ubiquitin

Poly-ubiquitinated

Post-translational modifications Histone ubiquitination

Promoter maize ubiquitin

Promoter ubiquitin

Proteasome ubiquitinated

Protein Degradation Ubiquitin

Protein degradation, ubiquitin-mediated

Protein modifiers, ubiquitin related

Protein ubiquitin

Proteins ubiquitin-tagged

Proteins ubiquitination

Proteolysis Ubiquitin proteasom

Regulation of Ubiquitin Conjugate Formation

Regulation via the Ubiquitin-Proteasome Pathway

Role of the Ubiquitin-Proteasome System

Salvage Pathways Recovering Mono-ubiquitin Adducts and Recycling Polyubiquitin

Small ubiquitin-like modifier

Small ubiquitin-like modifier (SUMO

Small ubiquitin-like modifier proteins

The SCF Ubiquitin E3 Ligase

The Structural Biology of Ubiquitin-Protein Ligases

The Ubiquitin-Proteasome System

The Ubiquitin-Proteasome System as a Target for Drug Development

The Ubiquitin-associated (UBA) Domain

Trimethyllysine in ubiquitin

Ubiquitin

Ubiquitin C-terminal Hydrolases (UCH)

Ubiquitin C-terminal hydrolase

Ubiquitin C-terminal hydrolases

Ubiquitin C-terminus

Ubiquitin Domains in Complex Proteins

Ubiquitin Isopeptide Hydrolysis

Ubiquitin Mms2-Ubcl3 complex

Ubiquitin Skpl-Skp2 complex

Ubiquitin Tags Proteins for Proteolysis

Ubiquitin Ubiquitinylation

Ubiquitin Ubiquitinylation Enzymes

Ubiquitin Ubiquitinylation Function

Ubiquitin Volume

Ubiquitin activity

Ubiquitin associated domain

Ubiquitin biochemistry

Ubiquitin bovine

Ubiquitin carboxy-terminal hydrolase

Ubiquitin carboxyl-terminal

Ubiquitin carboxyl-terminal hydrolase

Ubiquitin carboxyl-terminal hydrolases

Ubiquitin cascade

Ubiquitin catalysis mechanism

Ubiquitin classes

Ubiquitin complex

Ubiquitin complex proteins

Ubiquitin conjugation cascade

Ubiquitin core domain

Ubiquitin crystal structure

Ubiquitin domain detection

Ubiquitin domains

Ubiquitin endocytosis

Ubiquitin evolution

Ubiquitin fold

Ubiquitin function

Ubiquitin functional diversity

Ubiquitin fusion degradation

Ubiquitin gene expression

Ubiquitin genes

Ubiquitin hydrolase

Ubiquitin immunoreactivity

Ubiquitin in protein

Ubiquitin interacting motif

Ubiquitin interaction

Ubiquitin isopeptidase activity

Ubiquitin ligase

Ubiquitin ligase XIAP

Ubiquitin ligases

Ubiquitin proteasome proteolysis

Ubiquitin protein degradation system

Ubiquitin protein ligase

Ubiquitin protein ligases

Ubiquitin proteolytic pathway

Ubiquitin recognition domain

Ubiquitin structural biology

Ubiquitin structure

Ubiquitin substrate interactions

Ubiquitin system

Ubiquitin thioester

Ubiquitin unfolding

Ubiquitin vinyl sulfone

Ubiquitin, folding kinetics

Ubiquitin, proteins tagged with

Ubiquitin, proteolysis pathway mediation

Ubiquitin-Dependent Protein Degradation

Ubiquitin-activating enzyme

Ubiquitin-carrier protein

Ubiquitin-conjugating Machinery

Ubiquitin-conjugating enzyme

Ubiquitin-conjugating enzyme variant

Ubiquitin-conjugating ligases

Ubiquitin-independent Proteolysis

Ubiquitin-ligating enzyme

Ubiquitin-ligation enzyme

Ubiquitin-like Specific Proteases (ULP)

Ubiquitin-like domain

Ubiquitin-like proteins

Ubiquitin-like specific proteases

Ubiquitin-mediated degradation

Ubiquitin-mediated protein

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolytic system

Ubiquitin-proteasome pathway

Ubiquitin-proteasome system

Ubiquitin-proteosome system

Ubiquitin-related modifier

Ubiquitin-specific proteases

Ubiquitin/Proteasome

Ubiquitination

Ubiquitination

Ubiquitination cellular influence

Ubiquitination chromatin-modifying complexes

Ubiquitination enzymes

Ubiquitination process

Ubiquitination structure

Ubiquitination, of proteins

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