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Ubiquitin carboxyl-terminal

ZnFUBP Ubiquitin carboxyl-terminal hydrolase-like zinc finger E(MFP) 4(4) 4(4) ... [Pg.208]

Pickaet, C. M. and Rose, 1. A. Ubiquitin carboxyl-terminal hydrolase acts on ubiquitin carboxyl-terminal amides, J Biol Chem, 1985, 260, 7903-10. [Pg.212]

K. D. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases, J Pathol, 1990, 363, 153-60. [Pg.217]

Thiosulfate suUurtransferase Transitional endoplasmic reticulum ATPase Triosephosphate isomerase (TIM) Tropomyosin 3 Tubulin beta-1 chain Ubiquitin carboxyl-terminal hydrolase 5 Ubiquinol-cytochrome C reductase complex core protein I Vimentin Vimentin... [Pg.40]

Identifying altered canine and bovine proteins has proved to be particularly challenging since these species are poorly represented in current genomic databases. As a result of this, new bioinformatic tools (Multildent, http //expasy.org) have had to be developed to facilitate cross-species protein identification (Wilkins et al., 1998). The most significant change observed for bovine DCM was a sevenfold increase in the enzyme ubiquitin carboxyl-terminal hydrolase (UCH) (Weekes... [Pg.301]

PD is generally a sporadic disorder, but in a significant proportion of cases (10-15% in most studies) it runs in families without a clearcut Mendelian pattern. Currently, there have been 13 defined loci identified as associated with high-penetrant autosomal dominant or recessive PD, of which causative mutations in specific genes have been identified. These genes include a-synuclein, parkin, ubiquitin carboxyl-terminal esterase LI (UCH-Ll), PTEN-induced putative kinase 1 (PlNKl), DJ-1, and leucine-rich repeat kinase 2 (LRRK2). As outlined in Table 3, most of these mutations can be characterized by an early onset of disease. [Pg.69]

Castegna et al, 2003 Sultana et al, 2006b). Ubiquitin carboxyl-terminal hydrolase L-1 (UCH L-1), one of the components of the proteosomal pathway, was identified as an oxidized protein in the inferior parietal and hippocampal regions of AD, further suggesting a role for nitration in protein accumulation (Castegna et al., 2003 Sultana et al., 2006b). [Pg.593]

The PARKS-linked PD gene has been reported as the ubiquitin carboxyl-terminal hydrolase-Ll (UCHLl) located on chromosome 4pl3 (Leroy et al., 1998). UCHLl is a protein of 223 amino acids, 9 exons, and a transcript length of 1172 bps (Wilkinson et al., 1989) (Fig. 8). [Pg.718]

Naito S, Mochizuki H, Yasuda T, Mizuno Y, Furusaka M, Ikeda S, Adachi T, Shimizu HM, Suzuki J, Fujiwara S, Okada T, Nishikawa K, Aoki S, Wada K (2006) Chtiracterization of multimetric variants of ubiquitin carboxyl-terminal hydrolase LI in water by small-angle neutron scattering. Biochem Biophys Res Common 339 717-725... [Pg.746]

Nishikawa K, Li H, Kawamura R, Osaka H, Wang YL, Hara Y, Hirokawa T, Manage Y, Amano T, Noda M, Aoki S, Wada K (2003) Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase LI variants. Biochem Biophys Res Commun 304 176-183... [Pg.746]

WiUdnson KD, Lee KM, Deshpande S, Duerksen-Hughes P, Boss JM, Pohl J (1989) The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. Science 246 670-673 WUhams DR, Hadeed A, al-Din AS, Wreikat AL, Lees AJ (2005) Kufor Rtikeb disease autosomal recessive, levodopa-responsive parkinsonism with pyramidal degeneration, supranuclear gaze palsy, and dementia. Mov Disord 20 1264-1271... [Pg.753]

UCHL1 Ubiquitin carboxyl-terminal esterase LI (ubiquitin thiolesterase) 4pl4... [Pg.479]

UCHL3 Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 13q22.2... [Pg.479]


See other pages where Ubiquitin carboxyl-terminal is mentioned: [Pg.525]    [Pg.600]    [Pg.525]    [Pg.335]    [Pg.476]    [Pg.115]    [Pg.117]    [Pg.209]    [Pg.42]    [Pg.241]   


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