Ubiquitin-like specific proteases

The ubiquitin-7ike specific proteases (ULPs) are a third class of DUB first thought to act only on SUMO-related ubiquitin-like proteins. There are two yeast ULPs and seven human ULPs (also called sentrin specific proteases, or SENPs). Further analysis determined that ULPs have little or no activity on ubiquitin substrates, but one (SENPS) acts on NeddS [26, 37, 38]. Despite acting on non-ubiquitin substrates,... 

Li, S. j. and Hoghstrasser, M. The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein, Mol Cdl Biol, 2000, 20, 2367-77. 

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