Trioctyl phosphate

TrioctylPhosphate. Trioctyl phosphate [1806-54-8/, C24H 04P, has been employed as a specialty flame-retardant plasticizer for vinyl compositions where low temperature flexibHity is critical, eg, in military tarpaulins. It can be included in blends along with general-purpose plasticizers (qv) such as phthalate esters to improve low temperature flexibHity. 

A/B = alkylated ben2enes TBU = tetrabutyl urea TOP = trioctyl phosphate and DIBC = diisobutyl carbinol. See text. 

Also trioctyl trimellitate (TOTM). Also trioctyl phosphate (TOP). 

Tris-(2-ethylhexyl)phosphate (TEHP, tri-isooctylphosphate, "trioctyl" phosphate, [78-42-2 25103-23-5] M 434.6, b 186"/lmm, 219"/5mm, d 0.92042, n 1.44464. TEHP, in an equal volume of diethyl ether, was shaken with aqueous 5% HCl and the organic phase was filtered to remove... 

Gd gestational day (Gl) = gastric intubation (GO) = gavage in oil Hemato - hematological incr. = increased IPTPP = isopropyl triphenyl phosphate LD = lethal dose, 50% kill LOAEL = lowest-observed-adverse-effect level M = male MCV = mean corpuscular volume MCHC = mean corpuscular hemoglobin concentration mo = month(s) Musc/skel = musculoskeletal NOAEL = no-observed-adverse-effect level NS = not specified NTE = neurotoxic esterase RBC red blood cell Resp = respiratory TBEP = tributoxyethyl phosphate TBP = tributyl phosphate TMP = trimethyl phosphate TNBP = tri-n-butyl phosphate TOP = trioctyl phosphate wk = week(s) x = times yr = year(s). 

No gross or histological hepatic alterations were observed in rabbits exposed to <480 mg/kg/day or chickens exposed to up to 720 mg/kg/day, respectively, of Cellulube 220 for an acute duration (Carpenter et al. 1959). No hepatic effects were reported in rats exposed to 50 mg/kg/day of Pydraul 90E for an intermediate duration (Monsanto 1979). Several intermediate-exposure rat studies showed liver effects for organophosphate esters. Liver weight increases were shown for tributyl phosphate at 250 mg/kg/day (Laham et al. 1985 Oishi et al. 1982), trioctyl phosphate at 250 mg/kg/day (Oishi et al. 1982),... 

An aqueous solution of 0.02 M methyl acetate at 25 C was passed through a column of trioctyl phosphate ( on a cellulose base) which acted as an acid catalytst. The reaction is... 

In 1969, 31 subjects had ocular Instillations of either 0.12 or 0.25X CS In water with 0.5X polyaorbate 20 or 0.05- 1.0Z CS In trioctyl phosphate In their right eyes. The subjects experienced intense ocular Irritation and lacrlmatlon. Acute conjunctival Injection lasted 1 h. No fluorescein staining of the cornea was seen under ultraviolet Illumination. In one subject, corneal staining, visualized with the slit lamp, resolved In 24 h.34 35... 

The alkylated anthraquinone process accounts for over 95% of the world production of H202, mainly because the it operates under mild conditions and direct contact of 02 and H2 is avoided. In this process, 2-alkylanthraquinone (the alkyl group is typically an ethyl, terf-butyl or amyl group) is dissolved in a mixture of a non-polar solvent (C9-Cn alkylbenzene) and a polar solvent [Trioctyl phosphate (TOP), or tetrabutyl urea (TBU) or diisobutyl carbinol (DIBC)] and then hydrogenated over a precious metal (Pd or Ni) catalyst in a three-phase reactor (trickle bed or slurry bubble column) under mild reaction conditions (<5bar, <80 °C) to generate 2-alkylanthrahydroquinone [1-3, 5], The latter is then auto-oxidized with air in a... 

Other 2-ethylhexanol based plasticizers were introduced, including some which imparted outstanding low temperature flexibility—dioctyl adipate (DOA), dioctyl azelate (DOZ), dioctyl sebacate (DOS), and trioctyl phosphate (TOF). In addition, TOF showed high resistance to microorganisms which was important in military applications. Furthermore, TOF improved flame resistance. However, the mixed ester—octyl diphenyl phosphate—also introduced in the forties—was far superior and showed a better balance of low temperature performance and flame resistance than either TOF or the well-established plasticizer—tricresyl phosphate (TCP). Each of these found a market as a specialty plasticizer because of these specific performance attributes. None, however, was a serious threat to DOP on an overall price-performance basis. Rather, they were used to supplement the properties of DOP where its performance was inadequate. 

Group B consisted of 850 participants whose only potential exposure was to trioctyl phosphate (TEHP or TOP) and contained a large number of marine participants ... 

Rengstorff, R.H., Mershon, M.M. (1969a). CS in trioctyl phosphate effects on human eyes. Medical Research Laboratories Technical Report 4376. Edgewood Arsenal, MD. 

Potassium Nitrate 7783-08-6 Selenic Acid 78-42-2 Trioctyl Phosphate... 

Dibutyl phthalate isomers Dioctyl phthalate isomers Trioctyl phosphate Tris-ethylhexylphosphate Phenolic compounds... 

Tris-(2-ethylhexyl)phosphate (TEHP, tri-isooctylphosphate, "trioctyl" phosphate, [78-... 

Relatively Httle is known about industrial organophosphates, such as triphenyl phosphate, trioctyl phosphate, and tris(chloropropyl) phosphate. These compounds are used as plasticizers and flame retardants and are likely to reach the marine environment. Six organophosphates were detected in the water of Osaka Bay in concentrations ranging from 0.1 pg/1 to 1.3 pg/1. The compounds tris(2-chloroethyl)phosphate and tributyl phosphate were the most abundant [144]. 

The eye is a sensitive target organ of riot control agents. In studies14,15 on humans, CS (0.1% or 0.25% CS in water 1.0% CS in trioctyl phosphate), when placed or sprayed into the eyes, caused inability to open the eyes for 10 to 135 seconds. A transient conjunctivitis but no corneal damage as assessed by slitlamp biomicroscopy resulted. 

Rengstorff RH, Mershon MM. CS in Trioctyl Phosphate Effects on Human Eyes. Edgewood Arsenal, Md Medical Research Laboratories 1969. Technical Report 4376. 

The second group consists of plasticizers having polar groups attached to aliphatic chains and is called the polar aliphatic group. Examples are aliphatic alcohols and acid or alkyl esters of phosphoric acid (such as trioctyl phosphate). Their polar groups interact with polar sites on polymer molecules, but since their aliphatic part is rather bulky and flexible other polar sites on the polymer chain maybe screened by plasticizer molecules. This reduces the extent of intermolecular interactions between neighboring polymer chains, as shown in Figure 1.44b. 

Chem. Descrip. Trioctyl phosphate CAS 78-42-2 EINECS/ELINCS 201-116-6 Uses Plasticizer for PVC, rubber, paints, coatings solvent Features Low temp, plasticizer highly efficient solvent Reotan [Lambert ]... 

Phosphoric acid, triphenyl ester. See Triphenyl phosphate Phosphoric acid, tris (2-ethylhexyl) ester. See Trioctyl phosphate Phosphoric acid, tris (methylphenyl) ester Phosphoric acid, tritolyl ester. See Tricresyl phosphate Phosphoric acid, zinc salt (2 3). See Zinc phosphate Phosphorodithioic acid, mixed 0,0-bis (iso-butyl and pentyl) esters, zinc salt. See Zinc dialkyl dithiophosphate Phosphorous acid, cyclic neopentanetetrayl bis (2,4-di-t-butylphenyl) ester. See Bis (2,4-di-t-butylphenyl) pentaerythritol diphosphite Phosphorous acid, triisooctyl ester. See Triisooctyl phosphite Phosphorous acid triphenyl ester. See Triphenyl phosphite... 

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