Transforming growth factor 03 gene

Effects of pirfenidone on transforming growth factor-/ gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J. Pharmacol. Exp. Ther. 291 367-73... 

Takenaka, I.M. Hightower, L.E. (1993). Regulation of chicken hsp70 and hsp90 family gene expression by transforming growth factor beta 1. J. Cell Physiol. 155,54-62. 

Parola, M., Muraca, R, Dianzani, I., Barrera, G., Leonarduzzi, G., Bendinelli, P., Piccoletti, K and Poli, G. (1992). Vitamin-E dietary supplementation inhibits transforming growth factor 01 gene expression in the rat liver. FEBS Lett. 308, 267-270. 

Gharaee-Kermani M, Denholm EM, Phan SH. Costimulation of fibroblast collagen and transforming growth factor betal gene expression by monocyte chemoattractant protein-1 via specific receptors. J Biol Chem 1996 271(30) 17779-17784. 

Date M et al. Differential expression of transforming growth factor-/ and its receptors in hepatocytes and nonparenchy-mal cells of rat liver after CC14 administration. J Hepatol 1998 28 572-581. Frueh FW et al. Extent and character of Phenobarbital-mediated changes in gene expression in the liver. Mol Pharmacol 1997 51 363-369. 

Vidigal, P. G., Germer, J. J., and Zein, N. N., Polymorphisms in the interleukin-10, tumor necrosis factor-alpha, and transforming growth factor-betal genes in chronic hepatitis C patients treated with interferon and ribavirin, J. Hepatol., 36, 271, 2002. 

Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, et al Targeted disruption of the mouse transforming growth factor-pj gene results in multifocal inflammatory disease. Nature 1992 359 693-699. 

Luetteke NC, Phillips HK, Qiu TH et al 1994 The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev 8 399-413 Ma YJ, Jumer MP, Costa ME, Ojeda SR 1992 Transforming growth factor-alpha gene expression in the hypothalamus is developmentaUy regulated and linked to sexual maturation. Neuron 9 657—670... 

The expression of the ET-1 gene is increased by growth factors and cytokines, including transforming growth factor-B (TGF-B) and interleukin 1 (IL-1), vasoactive substances including Ang II and vasopressin, and mechanical stress. Expression is inhibited by nitric oxide, prostacyclin, and ANP. 

The Sertoli cells in the testis synthesize and secrete a variety of active proteins, including miillerian duct inhibitory factor, inhibin, and activin. As in the ovary, inhibin and activin appear to be the product of three genes that produce a common ot subunit and two subunits, A and B. Activin is composed of the two subunits ( ). There are two inhibins (A and B), which contain the a subunit and one of the subunits. Activin stimulates pituitary FSH release and is structurally similar to transforming growth factor-B, which also increases FSH. The inhibins in conjunction with testosterone and dihydrotestosterone are responsible for the feedback inhibition of pituitary FSH secretion. 

Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants. Am J Hum Genet, 68 551-561. 

Levine, A.E. Chakrabarty, S. (1992) Response of FR3T3 cells transformed by Ha-ras oncogene and epidermal growth factor gene to differentiation induction by A A -dimethylformamide. Int. J. Cancer, 50, 653-658... 

NF-icB, Nuclear factor-kappaB GFAP, glial fibrillary acidic protein /3-APP, /3-amyloid precursor protein TGF-/33, transforming growth factor-/33 Cdk4, cyclin-dependent kinase and p53, a tumor-suppressor gene. 

Fominaya, J., Uherek, C. and Weis, W. (1998) A chimeric fusion protein containing transforming growth factor-alpha mediates gene transfer via binding to the EGF receptor. Gene Ther., 5, 521-530. 

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