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Transforming growth factor-a

EGF family Epidermal growth factor Transforming growth factor-a... [Pg.192]

Epidermal growth factor, EGF Transforming growth factor-a, TGF-a ca 6 kD, EGF und TGF-a are up to 40 % identical Receptor tyrosine kinase. EGF-R is a produkt of the c-erbB proto-oncogene... [Pg.287]

Tan E, Shah H, Leister K, et al. Transforming growth factor-a (TGF-a) in a semisolid dosage form preservative and vehicle selection. Pharma Res 1993 10(8) 1238 1242. [Pg.212]

Lager, D. J., Slagel, D. D., and Palechek, P. L. 1994. The expression of epidermal growth factor receptor and transforming growth factor a in renal cell carcinoma. Mod. Pathol. 7 544-548. [Pg.327]

Chinese hamster ovary. bHuman chorionic gonadotropin. Venezuelan equine encephalitis virus. dEpidermal growth factor. Transforming growth factor a. [Pg.108]

C. Epidermal Growth Factors (EGF) and Transforming Growth Factor-a (TGF-a)... [Pg.24]

Transforming growth factor-a-Pseudomonas aeruginosa exotoxin A 40 (TGFa-PE40, Mr = 44,960) is a recombinant fusion protein synthesized in E. co/z.127,128 The growth factor moiety binds to surface epidermal growth factor (EGF) receptors on cancerous cells and is internalized where it releases the exotoxin domain into the cytosol.128 The toxin subunit catalytically inactivates the protein synthesis machinery of the cancer cell and the cell subsequently dies.129 It is a recombinant protein intended to be an anticancer therapeutic. [Pg.60]

C14. Cohen, D. W., Simak, R., Fair, W. R., Melamed, J., Scher, H. I., and Cordon-Cardo, C., Expression of transforming growth factor-a and the epidermal growth factor receptor in human prostate tissues. J. Urol. 152, 2120-2124 (1994). [Pg.143]

L14. Lui X. H., Wiley, H. S., and Meikle, A. W., Androgens regulate proliferation of human prostate cancer cells in culture by increasing transforming growth factor-a (TGF-a) and epidermal growth factor (EGF)/TGF-a receptor. J. Clin. Endocrinol. Metab. 77, 1472—1478 (1993). [Pg.151]

M33. Myers, R. B., Kudlow, J. E., and Grizzle, W. E., Expression of transforming growth factor a, epidermal growth factor and the epidermal growth factor receptor in adenocarcinoma of the prostate and benign prostatic hyperplasia. Mod. Pathol. 6,733-737 (1993). [Pg.153]

See other pages where Transforming growth factor-a is mentioned: [Pg.566]    [Pg.568]    [Pg.1355]    [Pg.473]    [Pg.481]    [Pg.158]    [Pg.53]    [Pg.27]    [Pg.210]    [Pg.85]    [Pg.17]    [Pg.252]    [Pg.106]    [Pg.22]    [Pg.1753]    [Pg.120]    [Pg.113]    [Pg.175]    [Pg.338]    [Pg.19]    [Pg.264]    [Pg.17]    [Pg.40]    [Pg.60]    [Pg.353]    [Pg.201]    [Pg.70]    [Pg.108]    [Pg.248]    [Pg.128]    [Pg.5]    [Pg.566]    [Pg.568]   
See also in sourсe #XX -- [ Pg.183 ]

See also in sourсe #XX -- [ Pg.173 , Pg.252 , Pg.254 , Pg.255 , Pg.256 , Pg.259 ]



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