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Monocyte chemoattractant protein

A number of adipokines are linked to inflammation and immunity (Fig. 1). This includes both leptin and adiponectin, and also a number of other key inflammatory proteins, particularly cytokines and chemokines [1]. The cytokines and chemokines encompass interleukin-1(3 (EL-1 (3), IL-6, DL-10, TNFa, monocyte chemoattractant protein-1 (MCP-1), and macrophage migration inhibitory factor (MIF). Other major inflammation-related adipokines include nerve growth factor (NGF), and acute phase proteins such as serum amyloid A and haptoglobin. In addition, adipocytes secrete plasminogen activator inhibitor-1 (PAI-1), which is an important thrombotic factor as well as an acute phase protein. [Pg.39]

White FA, Sun J et al (2005b) Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion. Proc Natl Acad Sci USA 102(39) 14092-14097... [Pg.86]

Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN (1998) Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. J Neuroimmunol 84 238-249 Simpson J, Rezaie P, Newcombe J, Cuzner ML, Male D, Woodroofe MN (2000) Expression of the beta-chemokine receptors CCR2, CCR3 and CCR5 in multiple sclerosis central nervous system tissue. J Neuroimmunol 108 192-200... [Pg.144]

Gong JH, Clark-Lewis I (1995) Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues. J Exp Med 181 631-640 Gonzalez-Scarano F, Martin-Garcia J (2005) The neuropathogenesis of AIDS. Nat Rev Immunol 5 69-81... [Pg.168]

Coughlan CM, McManus CM, Sharron M et al (2000) Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience 97 591-600 Cunha FQ, Lorenzetti BB, Poole S, Ferreira SH (1991) lnterleukin-8 as a mediator of sympathetic pain. Br J Pharmacol 104 765-767... [Pg.186]

Zhang J, De Koninck Y (2006) Spatial and temporal relationship between monocyte chemoattractant protein-1 expression and spinal glial activation following peripheral nerve injury. J Neurochem 97 772-783... [Pg.190]

Carroll SL, Frohnert PW (1998) Expression of JE (monocyte chemoattractant protein-1) is induced by sciatic axotomy in wild type rodents but not in C57BLAVld(s) mice. J Neuropathol Exp Neurol 57 915-930... [Pg.214]

Jung H, Toth PT, White FA, Miller RJ (2008) Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. J Neurochem 104 254-263... [Pg.215]

Toews AD, Barrett C, Morell P (1998) Monocyte chemoattractant protein 1 is responsible for macrophage recruitment following injury to sciatic nerve. J Neurosci Res 53 260-267 Toggas SM, MasUah E, Rockenstein EM, Rail GF, Abraham CR, Mucke L (1994) Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice. Nature 367 188-189... [Pg.219]

Westmoreland SV, Rottman JB, Williams KC, Lackner AA, Sasseville VG (1998) Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis. Am J Pathol 152 659-665 White FA, Sun J, Waters SM, Ma C, Ren D, Ripsch M, Steflik J, Cortiight DN, Lamotte RH, Miller RJ (2005) Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion. Proc Natl Acad Sci USA 102 14092-14097... [Pg.220]

Franci C, Gosling J, Tsou CL, Coughlin SR, Charo IF (1996) Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function. J Immunol 157 5606-5612... [Pg.242]

Gong JH, Ratkay LG, Waterfield JD, Clark-Lewis I (1997) An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model. J Exp Med 186 131-137... [Pg.243]

Myers SJ, Wong LM, Charo IF (1995) Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells. J Biol Chem 270 5786-5792... [Pg.247]

Desbaillets 1, Tada M, de Tribolet N, Diserens AC, Hamou ME, Van Meir EG (1994) Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro. Int J Cancer 58 240-247... [Pg.267]

Flatten M, Kretz A, Naumann U, Aulwurm S, Egashira K, Isenmann S, Weller M (2003) Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gUomas. Ann Neurol 54 388-392... [Pg.269]

Review] [67 refs]. Clin Diagn Lab Immunol 7 719-723 Bodnar RJ (2007) Endogenous opiates and behavior 2006. Peptides 28 2435-2513 Boekhoudt GH, Guo Z, Beresford GW, Boss JM (2003) Communication between NF-kappa B and Spl controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene. J Immunol 170 4139-4147... [Pg.332]

See other pages where Monocyte chemoattractant protein is mentioned: [Pg.40]    [Pg.82]    [Pg.137]    [Pg.224]    [Pg.8]    [Pg.23]    [Pg.24]    [Pg.29]    [Pg.35]    [Pg.36]    [Pg.44]    [Pg.45]    [Pg.46]    [Pg.49]    [Pg.145]    [Pg.169]    [Pg.186]    [Pg.187]    [Pg.187]    [Pg.190]    [Pg.218]    [Pg.219]    [Pg.220]    [Pg.223]    [Pg.240]    [Pg.241]    [Pg.247]    [Pg.248]    [Pg.250]    [Pg.252]    [Pg.264]    [Pg.268]    [Pg.316]    [Pg.316]   
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