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Transforming growth factor-alpha TGF

Hwang SJ, Beaty TH, Panny SR, Street NA, Joseph JM, Gordon S, McIntosh t, Francomano CA (1995) Association study of transforming growth factor alpha (TGF)-environment interaction in a population-based sample of infants with birth defects. Am J Epidemiol, 141 629-636. [Pg.148]

Two peptides that have received attention for their potential role in barrier maintenance are epidermal growth factor (EOF) and transforming growth factor-alpha (TGF-alpha). EGF is secreted in saliva and from duodenal glands, while TGF-alpha is produced by gastric epithelial cells. Both peptides bind to a common receptor and stimulate epithelial ceh proliferation. In the stomach they also enhance mucus secretion and inhibit acid production. [Pg.72]

Wagner CL, Ryan RM, Forsythe DE, Keenan A, Finkelstein JN. Secretion of transforming growth factor-alpha (TGF alpha) by postnatal rabbit alveolar macrophages. Pediatr Res 1995 38 49-54. [Pg.395]

Absher M, Sjostrand M, Baldor LC, Hemenway DR, Kelley J. Patterns of secretion of transforming growth factor-alpha (TGF-alpha) in experimental silicosis. Acute and subacute effects of cristobalite exposure in the rat. Reg Immunol 1993 5 225-231. [Pg.400]

Inhibition of protein kinase C aljlia (PKCa) with consequent inhibition of superoxide production by NADPH oxidase Inhibition of protein kinase C alpha (PKCa) via activation of protein phosphatase 2A (PP2A) or via direct binding to PKCa, activation of cellular release of transforming growth factor beta (TGF-P)... [Pg.130]

FIGURE 96-4. Pathophysiology of the hypercalcemia of malignancy. PTHrP, parathyroid hormone-related protein TGF-P, transforming growth factor P TNF-a, tumor necrosis factor alpha Ca2+, calcium IL-1, interleukin 1 IL-2, interleukin 2. [Pg.1483]

Flatten M, Wick W, Wild-Bode C, et al. Transforming growth factors beta(l) [TGF-beta(l)] and TGF-beta(2) promote glioma cell migration via up-regula-tion of alpha (V)beta(3) integrin expression. Biochem Biophys Res Commun 2000 268(2) 607-611. [Pg.310]

SPMS secondary-progressive multiple sclerosis SSPE subacute sclerosing panencephalitis TGF-/S transforming growth factor /3 TLI total lymphoid irradiation TNF-a tumor necrosis factor alpha WHO World Health Organization... [Pg.1019]

RA rheumatoid arthritis, RNS reactive nitrogen species, ROS reactive oxygen species, SF synovial fluid, SOD superoxide dismutase, SPAMl sperm adhesion molecule-1, TGF- transforming growth factor beta, TNB 5-thio-2-nitrobenzoic acid, TNF-a tumor necrosis factor alpha, UDP uridine diphosphate... [Pg.4]

Sampson JH, Akabani G, Archer GE et al. (2003) Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol 65 27-35... [Pg.294]


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