TNF alpha

Palladino MA, Bahjat FR, Theodorakis EA et al (2003) Anti-TNF-alpha therapies the next generation. Nat Rev Drug Discov 2 736-746... 

Term to UltraLink tumor necrosis factor alpha Concept Type TARGET Normalized term TNF alpha Synonyms ... 

Wagner R, Myers RR (1996) Endoneurial injection of TNF-alpha produces neuropathic pain behaviors. Neuroreport 7(18) 2897-2901... 

Han Y, He T, Huang DR, Pardo CA, Ransohoff RM (2001) TNF-alpha mediates SDF-1 alpha-induced NF-kappa B activation and cytotoxic effects in primary astrocytes. J Clin Invest 108 425 35... 

Ahn SY, Cho CH, Park KG, Lee HI, Lee S, Park SK, Lee IK, Koh GY (2004) Tumor necrosis factor-alpha induces fractaUdne expression preferentially in arterial endothelial cells and mithramycin A suppresses TNF-alpha-induced fractaUdne expression. Am J Pathol 164 1663-1672 Alfano M, Schmidtmayerova H, Amelia CA, Pushkarsky T, Bukrinsky M (1999) The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains, [see comments]. J Exp Med 190 597-605 Ambrosini E, Alois F (2004) Chemokines and glial cells a complex network in the central nervous system. [Review] [239 refs]. Neurochem Res 29 1017-1038 Azuma Y, Ohura K (2002) Endomorphins 1 and 2 inhibit IL-10 and IL-12 production and innate immune functions, and potentiate NE-kappaB DNA binding in THP-1 differentiated to macrophagelike cells. Scand J Immunol 56 260-269... 

Marcario JK, Riazi M, Adany I, Kenjale H, Fleming K, Marquis J, Nemon O, Mayo MS, Yankee T, Narayan O, Cheney PD (2008) Effect of morphine on the neuropathogenesis of SlVmac infection in Indian Rhesus Macaques. J Neuroimmune Pharmacol 3 12-25 Mattson MP, Haughey NJ, Nath A (2005) CeU death in HIV dementia. Cell Death Differ 12 893-904 Mayne M, Bratanich AC, Chen P, Rana F, Nath A, Power C (1998) HlV-1 tat molecular diversity and induction of TNF-alpha implications for HIV-induced neurological disease. Neuroimmunomodulation 5 184-192... 

Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M. TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp Dermatol 2004 13 551-557. 

Feldmann M, Maini RN. Anti-TNF alpha therapy of rheumatoid arthritis what have we learned Annu Rev Immunol 2001 19 163-196. 

Redlich K, Hayer S, Ricci R, et al. Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest 2002 110(10) 1419-1427. 

Chabaud M, Page G, Miossec P. Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis regulation by soluble receptors and Th2 cytokines. J Immunol 2001 167(10) 6015-6020. 

McNeamey T, Baethge BA, Cao S, Alam R, Lisse JR, Westlund KN. Excitatory amino acids, TNF-alpha, and chemokine levels in synovial fluids of patients with active arthropathies. Clin Exp Immunol 2004 137(3) 621-627. 

Fig. 3. The role of FKN/CX3R1 in inducing atherosclerosis may involve two mechanisms. The first is the release of soluble FKN through cleavage of membrane-expressed FKN by TNF-alpha converting enzyme (TACE). Soluble FKN is then able to attract circulating monocytes and effector T cells expressing CX3CR1. The second mechanism is that of firm adhesion of circulating cells to membrane-bound FKN.

Garcia GE, Xia Y, Chen S, et al. NF-kappaB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-lbeta, TNF-alpha, and LPS. J Leukoc Biol 2000 67(4) 577-584. 

Ahn S Y, Cho CH, Park KG, et al. Tumor necrosis factor-alpha induces fractalkine expression preferentially in arterial endothelial cells and mithramycin A suppresses TNF-alpha-induced fractalkine expression. Am J Pathol 2004 164(5) 1663-1672. 

Ludwig A, Berkhout T, Moores K, Groot P, Chapman G. Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TNF-alpha and is modulated by metalloproteinase activity. J Immunol 2002 168(2) 604-612. 

Booth M, Mwatha JK, Joseph S, et al. Periportal fibrosis in human Schistosoma mansoni infection is associated with low IL-10, low IFN-gamma, high TNF-alpha, or low RANTES, depending on age and gender. J Immunol 2004 172(2) 1295-1303. 

Zujovic V, Benavides J, Vige X, et al. Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia 2000 29 305-315. 

H13. Hamilton, G., Hofbauer, S and Hamilton, B., Endotoxin, TNF-alpha, interleukin-6 and parameters of the cellular immune system in patients with intraabdominal sepsis. Scand. J. Infect. Dis. 24,361-368 (1992). 

Wang, X. C., C. Allen et al. (2007). Retinoic acid enhances the production of IL-10 while reducing the synthesis of IL-12 and TNF-alpha from LPS-stimulated monocytes/macrophages. J. Clin. Immunol. 27(2) 193-200. 

Gordon, J.R. and Galli, S.J. (1990) Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin. Nature 346, 274-276. 

Homung, F., Scala, G. and Lenardo, M.J. (2000) TNF-alpha-induced secretion of C-C chemokines modulates C-C chemokine receptor 5 expression on peripheral blood lymphocytes. Journal of Immunology 164, 6180-6187. 

Joyce, D.A. and Steer, J.H. (1996) IL-4, IL-10 and IFN-gamma have distinct, but interacting, effects on differentiation-induced changes in TNF-alpha and TNF receptor release by cultured human monocytes. Cytokine 8, 49-57. 

Lukacs, N.W., Stricter, R.M., Chensue, S.W., Widmer, M. and Kunkel, S.L. (1995) TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation. Journal of Immunology 154, 5411-5417. 

Additional applications of BSOCOES and sulfo-BSOCOES include investigations of the cellular and subcellular distribution of the type II vasopressin receptor (Fenton et al., 2007), TNF-alpha (Grinberg et al., 2005), and studying mechanisms in the control of plasmid replication (Das et al., 2005). 

Brandt, J. and Braun, J. 2006. Anti-TNF-alpha agents in the treatment of psoriatic arthritis. Expert Opinion on Biological Therapy 6(2), 99-107. 

Kwan TS, Padrines M, Theoleyre S, Heymann D, Fortun Y (2004) IL-6, RANKL, TNF-alpha/IL-1 interrelations in bone resorption pathophysiology. Cytokine Growth Factor Rev 15 49-60... 

Cenci S, Weitzmann MN, Roggia C, Namba N, Novack D, Woodring J, Pacifici R (2000) Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest 106 1229-1237... 

Araya, A.V. et al., Ex vivo lipopolysaccharide (LPS)-induced TNF-alpha, IL-lbeta, IL-6 and PGE2 secretion in whole blood from type 1 diabetes mellitus patients with or without aggressive periodontitis, Eur. Cytokine Netw., 14, 128, 2003. 

Caux, C. et al., GM-CSF and TNF-alpha cooperate in the generation of dendritic Langer-hans cells, Nature, 360, 258-261, 1992. 

Arrighi, J.F.et al., A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers. J. Immunol., 166, 3837, 2001. 

Maier, L. A., et al., High beryllium-stimulated TNF-alpha is associated with the -308 TNF-alpha promoter polymorphism and with clinical severity in chronic beryllium disease, Am. J. Respir. Crit. Care Med., 164, 1192, 2001. 

Knight, D.M. et al., Construction and initial characterization of mouse human chimeric anti TNF alpha antibody, Molecular Immunol., 30, 1443, 1993. 

Mier, J.W. et al., Induction of circulating tumor necrosis factor (TNF-alpha) as the mechanism for the febrile response to interleukin-2 (IL-2) in cancer patients, J. Clin. Immunol., 8, 426, 1988. 

Chung, Y. J., Zhou H.R., and Pestka J.J. Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-alpha expression by deoxynivalenol (vomitoxin). Toxicol. Appl. Pharmacol. 193,188, 2003. 

Wong, S., Schwartz R.C., and Pestka J.J. Superinduction of TNF-alpha and IL-6 in macrophages by vomitoxin (deoxynivalenol) modulated by mRNA stabilization. Toxicology 161, 139, 2001. 

Ayub, S., Verma, J., and Das, N., Effect of endosulfan and malathion on lipid peroxidation, nitrite and TNF-alpha release by rat peritoneal macrophages, Int. Immunopharmacol., 3, 1819, 2003. 

Mohan, A.K. et al., Drug-induced systemic lupus erythematosus and TNF-alpha blockers, Lancet 360,646, 2002. 

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