Technical pesticide

Agricultural (Ag) formulations that are commonly diluted and applied by means of spray equipment include water soluble liquids, emulsifiable concentrates, wettable powders, and flowable suspensions. The choice of which formulation to develop normally depends upon the solubility properties of the technical pesticide. Scientists often must also consider manufacturing costs, field efficacy and product toxicity. 

The majority of publications on pesticide analysis deal with terminal residues and their determination. From a practical standpoint, the determination of the active ingredient in a technical pesticide or a formulation is equally important, if not always apparently so scientifically challenging. In recent years, new dimensions have been added to the problem by regulatory requirements, and it has been recognized that certain contaminants, present in manufactured products, might present potential risks to man and the environment. From a practical standpoint, the manufacture and sale of pesticide products must be linked at all times to an analytical control system capable of adequately measuring active ingredients, since fluctuations... 

Specifications for formulated or technical pesticides must be based on satisfactory analytical methods. Collaborative study methods that are acceptable to a number of international organizations are available through CIPAC-AOAC cooperation. Internationally, more effective use of current analytical methodology could result from increased efforts towards harmonization of methods and terminology. 

Although relatively simple analytical methods are sometimes useful for formulation analysis, it is important to recognize the problems inherent in non-specific methods and also the need to detect and measure potentially harmful contaminants in technical pesticides or formulations. 

ISI is available in hard copy and electronically at EPA s headquarters and regional Hbraries, and through the National Technical Information Service (NTIS). The electronic form may be installed on IBM PC-compatible computers or placed on local area networks, and mn under Microsoft WINDOWS or WordPerfect s Library program. The Macintosh version is no longer available. The 1993 update will include the ISI hardcopy, PC disks, and the PC system user manual. EPA also pubHshes ACCESS EPA, which provides sources of information, databases, and pubHcations within the EPA. Chapter 5 of that pubhcation includes important environmental databases in air and soHd waste, pesticides and toxic substances, water, and cross-program (110). EPA also provides databases accessible through EPA Hbraries, which describe the private EPA and commercial databases available to Hbrary users (111). 

Acetophenone can react with formaldehyde to yield light-resistant resins which are used as additives in nitrocellulose paints. It is also used as a photoinitiator, and in the pharmaceuticals, perfumery, and pesticide industries (344). It can be hydrogenated to 1-phenylethanol which is used for the production of aromatic ester fragrances (345). Technical-grade acetophenone is available at 2.29/kg perfume-grade acetophenone was 6.50/kg in October 1994. 

FIFRA Sections 3 and 4 pertain to registration and reregistration of pesticides, with clearly defined data requirements as outlined in Tide 40 of the US. Code of federal Regulations (51). About 120 different studies are Hsted, most of which are to be done on technical-grade active ingredients (TGAIs). 

Pollution Prevention and Abatement Pesticides Manufacturing." Draft Technical Background Document. Environment Department, Washington, D.C. 

Methyl parathion is a pesticide that is used to kill insects on crops. Usually, it is sprayed on the crops. Methyl parathion comes in two forms a pure form of white crystals and a technical-grade solution (brownish liquid), which contains methyl parathion (80%) and inactive ingredients in a solvent. The technical-grade methyl parathion smells like rotten eggs or garlic. Methyl parathion is a manufactured chemical, so it is found in the environment only as a result of its manufacture or use. Methyl parathion has been manufactured in the United States since 1952 and has been used to kill insects on many types of crops since this time. Because methyl... 

EPA. 1979. Water-related environmental fate of 129 priority pollutants. Vol. I Introduction and technical background, metals and inorganics, pesticides and PCB s. Washington, DC U.S. Environmental Protection Agency, Office of Water Planning and Standards. EPA-440/4-79-029a, 27.1-27.16. 

FAOAVHO. 1976. Pesticide residues in food. Report of the 1975 Joint Meeting of the FAO Working Party of Experts on Pesticides Residues and the WHO Expert Committee on Pesticide Residues. Geneva, Switzerland Food and Agricultural Orgaiuzafion of the United Nations and World Health Organization. FAO Plant Production and Protection Series no. 1, WHO Technical Report Series no. 592. 

JoshiHC. 1987. Pesticide residues in some fish ponds in West Bengal (India). Technical Annual-Indian Association for Water Pollution Control 14 35-38. 

This far into a nitrosamine symposium it should hardly be necessary to point out that nitrosamines are technically just one of a group of Ji-nitroso compounds that also includes nitros-amides, nitrosocarbamates, nitrosoureas, etc. Or that nitrosa-table pesticides encompass all the categories just mentioned and more. Or that many diverse pesticides, including herbicides, insecticides, and fungicides have been converted to Ji-nitroso derivatives in the laboratory (a recent review contained a 3-page, probably incomplete, compilation), or that some of the Ji-nitroso compounds thus synthesized were determined to be carcinogenic in test animals or mutagenic in various assays. 

Similarly, low volume chemicals are classified according to whether they are sold primarily on the basis of specification or performance. Specialties are generally formulations that are sold on the basis of their performance and their prices reflect their value rather than cost of production. Producers of specialty chemicals often provide extensive technical service to their customers. Examples of specialty chemicals include pharmaceuticals, pesticides, flavours and fragrances, specialty polymers, etc. Fine chemicals, on the other hand, are produced to customer specifications and are often intermediates or active ingredients for specialty chemicals, e.g. pharmaceutical and agrochemical intermediates and bulk actives. 

Accurate, precise and sensitive analytical methods are important to the collection of data needed for regulatory decisions about pesticide registration. This article describes the various components of analytical method development, validation and implementation that affect the collection of pesticide residue distribution data for regulatory assessment of environmental fate and water quality impacts. Included in this discussion are both the technical needs of analytical methods and the attributes of study design and sample collection needed to develop data that are useful for regulatory purposes. 

The ECL evaluates analytical methods for detecting pesticide residues in the environment to ensure that the methods are suitable for monitoring pesticide residues in soil and water. State, tribal and federal laboratories may access an Index of Environmental Chemistry Methods for a list of available methods. The ECL also provides the State pesticide laboratories with technical and QA support and training in pesticide analytical chemistry. 

Much misunderstanding can be avoided by sending technical men to give first-hand information where export is desired. Some customer service in foreign markets by technicians would pay excellent dividends in the increased use of pesticides. 

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