Surfactants hydrotropes

Pharmaceutical solutions might appear to be extremely simple systems, but it is in the solution state that degradation takes place most rapidly, and the solubilisation of poorly soluble compounds is often very difficult. It is ideal if a dmg can be formulated as a simple stable aqueous solution when required for injection, but resort to additives such as water-miscible solvents and surfactants, hydrotropes and cyclodextrins to increase the water solubility of the drug complicates the formulation. Here we deal with simple solutions. Some of the special problems related to peptide and protein solubility are discussed in Chapter 11. [Pg.140]

Comprise surfactant, hydrotrope, and unsaturated terpene alcohol disinfect dishware cleaning... [Pg.222]

The mechanism by means of which hydrotropes operate in surfactant solutions was elucidated by Friberg and coworkers (1970, 1971 Cox, 1981), who showed that it is due to the inhibition of the formation of surfactant liquid-crystalline phases by the hydrotrope. Since they have structures similar to those of surfactants, hydrotropes can form mixed micellar structures with surfactants. However, since their hydrophilic heads are large and their hydrophobic groups are small (their V)/ Icdo ratio [Chapter 3, Section II] is liquid-crystalline structures and thus inhibit the formation of the latter. This destruction or inhibition of the liquid-crystalline phase increases the solubility of the surfactant in the aqueous phase and the capacity of its micellar solution to solubilize material. Hydrotropic action occurs at concentrations at which the hydrotrope self-associates to form these mixed structures with the surfactant (Gonzalez, 2000). [Pg.189]

Alkali Surfactant MM. [Exxon/Tomah] Caustic surfactant hydrotrope used in alkaline formulations for hard surface cleaning solubilizer. [Pg.17]

Dissolver GX Grades. [Hoechst AG] All laryl polyglycol ethers surfactants, hydrotropes for liq. cleaners. [Pg.109]

Phospholan [HarcrosUK] Phoqthate esters surfactant hydrotrope, wetting agent detergent dispersant coupling agent emulsifier fex textiles, drycleaning, industrial and domestic cleaners, metal cleaning, emulskm polymerization. [Pg.280]

Phosphoteric T-C6. [Mona Industries] Substituted carboxylated cocoimid-azrdine orgam hosphate surfactant hydrotrope fix cleaning formulations. [Pg.280]

ACS 60 Ammonium cumenesulfonate Ammonium cumenesulphonate Benzenesulfonic acid, (1-methylethyl)-, ammonium salt Benzenesulphonic acid, (1-methylethyl)-, ammonium sail EINECS 253-519-1 Eltesol AC60 (1-Methylethyl)benzenesulfonic acid, ammonium salt. Surfactant, hydrotrope for agricultural applications. Mydrotrope, solubilizer for personal care applications. Albright Wilson UK Ltd. CK Wilco Corp. Rewo. [Pg.33]

Uses Emulsifier, solubilizer, solvent, detergent, and wetting agent for oil-based systems dispersant in oil and water-based systems in dry-cleaning surfactants hydrotrope for liq. detergents latex emulsifier ... [Pg.1162]

Uses Surfactant, hydrotrope in cosmetics Manuf./Distrib. Aldrich http //www.sigma-aidrich.com] Sigma... [Pg.237]

Cocoimidazoline sulfobetaine. See Sodium cocoamphohydroxypropyl sulfonate Cocoiminodiglycinate CAS 97659-51-3 EINECS/ELINCS 307-456-2 Properties Amphoteric Uses Surfactant, hydrotrope, detergent for industrial applies. [Pg.1018]

Empirical C22H43NO2 C18H36O2 Uses Surfactant in cosmetics Isostearamidopropylamine oxide Synonyms Amides, isostearic, N-[3-(dimethylamino) propyl], N-oxide N-[3-(Dimethylamino) propyl] isooctadecanamide, N-oxide Isooctadecanamide, N-[3-(dimethylamino) propyl]-, N-oxide Classification Aliphatic amine oxide Empirical C23H48N2O2 Uses Surfactant, hydrotrope, foam booster/stabilizer, thickener, lubricant, conditioner, vise, builder in cosmetics, household prods., janitorial prods. wetting agent for cone, electrolyte sol ns. [Pg.2272]

Uses Surfactant, hydrotrope, cleansing agent, foaming agent, vise, builder in cosmetics Trade Name Synonyms Incromine Oxide Mink t[Croda Inc http //www.croda.com] Minkamidopropyl betaine Synonyms N-(Carboxymethyl)-N,N-dimethyl-3-[(1-oxomink) amino]-1-propanaminium hydroxide, inner salt Minkamide propylbetaine Minkamidopropyl dimethyl glycine 1-Propanaminium, N,N-dimethyl-N-carboxymethyl-3-amino-, N-mink oil acyl derive., hydroxides, inner salts Classification Zwitterion (inner salt)... [Pg.2719]

Uses Prep, of food starch modified oil-phase corrosion inhibitor crosslinking curing agent for epoxy resins aikyd resin modifier surfactant hydrotrope... [Pg.2932]

Synonyms POE (7) hydrogenated castor oil Definition PEG deriv. of hydrogenated castor oil with avg. 7 moles of EO Properties Nonionic Toxicology TSCA listed Uses Surfactant, hydrotrope, emulsifier, softener in cosmetics and pharmaceuticals Trade Name Synonyms Arlacel 989 [Uniqema] Cremophor WO 7 [BASF http //wvw.basf.com, BASF AG http //www.basf.de], Croduret 7 Special [Croda Chem. Ltd http //www.croda.co.uk, Croda Oleochems.] Dehymuls HRE 7 [Cognis/Care Chems. Cognis KGaA/Care Chems.] Emalex HC-7 [Nihon Emulsion http //www.mhon-emulsion.co.jp]... [Pg.3128]

Part Two, Surfactants, contains chapters on the four major classes of surfactants, i.e. anionics, nonionics, cationics and zwitterionics, as well as chapters on polymeric surfactants, hydrotropes and novel surfactants. The physico-chemical properties of surfactants and properties of liquid crystalline phases are the topics of two comprehensive chapters. The industrially important areas of surfactant-polymer systems and environmental aspects of surfactants are treated in some detail. Finally, one chapter is devoted to computer simulations of surfactant systems. [Pg.604]

Surfactants, hydrotropes, and sequestering agents are analyzed without sample pretreatment in liquid detergent by NMR spectroscopy and phosphorus species present in detergents are quantified by NMR spectrometry. [Pg.4718]

By the reaction of cumene with sulfuric acid, in a manner similar to toluene sul-fonation (see Chapter 6.4), cumenesulfonic acid is obtained, which, after neutralization with sodium hydroxide in aqueous solution, is used extensively as a surfactant (hydrotrope). [Pg.296]

MONA INDUSTRIES, INC. MONATROPE Surfactant Hydrotropes MONATROPE 1250 ... [Pg.309]

MONATROPE 1250 is a highly versatile, low foaming surfactant hydrotrope which is very effective in formulating alkaline built liquid detergent concentrates. It is an excellent coupling agent for nonionic and other surfactants in high concentrations of electrolytes. MONATROPE 1250 is not recommended for use in low pH acidic systems. [Pg.309]

Uses Surfactant, hydrotrope, detergent for Industrial applies. [Pg.102]

Uses Surfactant hydrotrope, foam builder, dispersant in surfactant systems Features May be used in either cationic/nonionic formulatons Properties Cl. yel. liq, easily sol. in cold and hot water, methanol, and acetone water, dens. 1.07 g/cm vise. 45 mPas pour pt. -7 C flash pt. (PMCC) >100 C... [Pg.103]

Uses Surfactant, hydrotrope in aq. aikaiine cieaning prods, for hard surf, cieaning, acid cieaners... [Pg.159]

Uses Surfactant, hydrotrope used in heavy-duty, alkaline industrial detergent terns, textile wet processing, pulp deresination, dedusting agents and corrosion inhibitors... [Pg.227]

Uses Surfactant, hydrotrope In highly built Iiq. detergents solubilizer for nonionics and surfactants In high electrolyte applications Features Low foaming... [Pg.268]

Uses Surfactant, hydrotrope for anionics or nonionics, wetting agent, detergent for aikaiine buiit iiq. detergents, aii-purpose hard-surf, deaners, spray metai cieaners, floor scrubbers, wax strippers... [Pg.274]

CAS 37475-88-0 EINECS/ELINCS 253-519-1 Uses Surfactant, hydrotrope for agric. applies. [Pg.395]

CAS 94441-92-6 EINECS/ELINCS 305-318-6 Uses Surfactant hydrotrope wetting agent Features Low foaming aikaiine-stabie Heloxyl AP 30 [Mosseiman NV Chempri]... [Pg.528]

Uses Surfactant hydrotrope wetting agent foaming agent Features High foaming Heloxyl ASD 50 [Mosseiman NV]... [Pg.528]

Uses High foaming surfactant, hydrotrope for household and industrial hard surf, cleaners, shampoos, bubble bath, mild skin cleansers, down holefoamers, air drilling textile wetting agent Features Stable to acid and alkali... [Pg.747]

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