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Solutions pharmaceutical

Ion chromatography is widely employed in a number of areas of pharmaceutical analysis. The high sensitivity of suppressor-based ion chromatography makes it an ideal choice for the analysis of deionized water used in the preparation of solution pharmaceuticals and as a process fluid for the preparation of pharmaceuticals. Depending upon the... [Pg.248]

Three diverse groups of compounds can be usefully considered for their impact, but the need to be able to separate them from aqueous solution Pharmaceuticals, BP A, and food dyes. These will be considered in succession. [Pg.135]

Amrinone lactate is physically and chemically incompatible with alkaline solutions. Pharmaceuticals that are incompatible include digoxin, potassium chloride, procainamide hydrochloride, propranolol hydrochloride, verapamil hydrochloride, sodium chloride, and glucose solutions containing frusemide.101... [Pg.347]

Intermediate solutions Pharmaceutical solutions are used as intermediates for manufacturing other preparations. Aromatic water is used as a flavoring agent and peppermint and anise waters have some carminative properties. These are manufactured as concentrated waters and are diluted before use. Infusions are prepared by extracting the drug using 25% alcohol without heat. Extracts are similar to infusions, but are... [Pg.994]

Injectable products, ophthalmic products, and inhalation solutions Pharmaceutical ingredients Purified water Manufacturing environment Products As above Loop and taps daily Every shift in critical aseptic processing areas Every batch with the exception of terminally sterilized products approved for parametric release... [Pg.2787]

Lipinski, C.A. (2004) Solubility in water and DMSO issues and potential solutions. Pharmaceutical Profiling in Drug Discovery, 1, 93-125. [Pg.30]

Sodium salicylate tablets Solutions, pharmaceutical Spirits, pharmaceutical Suppositories Syrups, pharmaceutical Tablets, pharmaceutical Thyroid preparations... [Pg.458]

LM Her, M Deras, SL Nail. Electrolyte-induced changes in glass transition temperatures of freeze-concentrated solutes. Pharmaceutical Research 12 768, 1995. [Pg.164]

G Gomez, M Pikal, N Rodriguez-Homedo. Effect of initial buffer composition on pH changes during far-from-equilibrium freezing of sodium phosphate buffer solutions. Pharmaceutical Research 18 90-97, 2001. [Pg.164]

Where industrial problems vary by activity, policy must vary too selective intervention is an essential element of industrial poUcy. ball and Wangwe (1997) argued this point nearly 20 years ago it remains true today that distinct sectoral problems require distinctive sectoral solutions. Pharmaceuticals share characteristics with Tanzania-based industry generally but also face characteristic challenges (see also Chapter 1). Furthermore, some of the firms problems, as the manufacturer quoted above implies, are policy-based and distinctive to the pharmaceutical and medical supplies sectors. Furthermore, clusters of firms create mutual benefits in terms of knowledge flows and spill-overs (Nadvi and Haider, 2007 Page, 2012 see also Chapter 2), and Tanzania risks losing these benefits as the number of firms falls. Turnaround for this sector needs to be policy-led. [Pg.54]

Sorbitol is manufactured by the reduction of glucose in aqueous solution using hydrogen with a nickel catalyst. It is used in the manufacture of ascorbic acid (vitamin C), various surface active agents, foodstuffs, pharmaceuticals, cosmetics, dentifrices, adhesives, polyurethane foams, etc. [Pg.368]

The purity of a pharmaceutical preparation of sulfanilamide, C6H4N2O2S, can be determined by oxidizing the sulfur to SO2 and bubbling the SO2 through H2O2 to produce H2SO4. The acid is then titrated with a standard solution of NaOH to the bromothymol blue end point, where both of sulfuric acid s acidic protons have been neutralized. Calculate the purity of the preparation, given that a 0.5136-g sample required 48.13 mL of 0.1251 M NaOH. [Pg.305]

Industrial Analysis UV/Vis molecular absorption is used for the analysis of a diverse array of industrial samples, including pharmaceuticals, food, paint, glass, and metals. In many cases the methods are similar to those described in Tables 10.6 and 10.7. For example, the iron content of food can be determined by bringing the iron into solution and analyzing using the o-phenanthroline method listed in Table 10.6. [Pg.397]

Description of Method. The amount of chlorpromazine in a pharmaceutical formulation is determined voltammetrically at a graphite working electrode in a nonstirred solution. Calibration is achieved using the method of standard additions. [Pg.526]

The elution order for neutral species in MEKC depends on the extent to which they partition into the micelles. Hydrophilic neutrals are insoluble in the micelle s hydrophobic inner environment and elute as a single band as they would in CZE. Neutral solutes that are extremely hydrophobic are completely soluble in the micelle, eluting with the micelles as a single band. Those neutral species that exist in a partition equilibrium between the buffer solution and the micelles elute between the completely hydrophilic and completely hydrophobic neutrals. Those neutral species favoring the buffer solution elute before those favoring the micelles. Micellar electrokinetic chromatography has been used to separate a wide variety of samples, including mixtures of pharmaceutical compounds, vitamins, and explosives. [Pg.606]

Because of these characteristics electromagnetic flow meters have been widely appHed to the measurement of difficult Hquids such as raw sewage and wastewater flows, paper pulp slurries, viscous polymer solutions, mining slurries, milk, and pharmaceuticals. They ate also used in less demanding apphcations such as the measurement of large domestic water volumes. [Pg.65]

History. Methods for the fractionation of plasma were developed as a contribution to the U.S. war effort in the 1940s (2). Following pubHcation of a seminal treatise on the physical chemistry of proteins (3), a research group was estabUshed which was subsequendy commissioned to develop a blood volume expander for the treatment of military casualties. Process methods were developed for the preparation of a stable, physiologically acceptable solution of alburnin [103218-45-7] the principal osmotic protein in blood. Eady preparations, derived from equine and bovine plasma, caused allergic reactions when tested in humans and were replaced by products obtained from human plasma (4). Process studies were stiU being carried out in the pilot-plant laboratory at Harvard in December 1941 when the small supply of experimental product was mshed to Hawaii to treat casualties at the U.S. naval base at Pead Harbor. On January 5, 1942 the decision was made to embark on large-scale manufacture at a number of U.S. pharmaceutical plants (4,5). [Pg.526]

Uses of gelatin are based on its combination of properties reversible gel-to-sol transition of aqueous solution viscosity of warm aqueous solutions abUity to act as a protective coUoid water permeabUity and insolubUity in cold water, but complete solubUity in hot water. It is also nutritious. These properties are utilized in the food, pharmaceutical, and photographic industries. In addition, gelatin forms strong, uniform, clear, moderately flexible coatings which readily sweU and absorb water and are ideal for the manufacture of photographic films and pharmaceutical capsules. [Pg.206]

Heat Exchangers Using Non-Newtonian Fluids. Most fluids used in the chemical, pharmaceutical, food, and biomedical industries can be classified as non-Newtonian, ie, the viscosity varies with shear rate at a given temperature. In contrast, Newtonian fluids such as water, air, and glycerin have constant viscosities at a given temperature. Examples of non-Newtonian fluids include molten polymer, aqueous polymer solutions, slurries, coal—water mixture, tomato ketchup, soup, mayonnaise, purees, suspension of small particles, blood, etc. Because non-Newtonian fluids ate nonlinear in nature, these ate seldom amenable to analysis by classical mathematical techniques. [Pg.495]

Other than fuel, the largest volume appHcation for hexane is in extraction of oil from seeds, eg, soybeans, cottonseed, safflower seed, peanuts, rapeseed, etc. Hexane has been found ideal for these appHcations because of its high solvency for oil, low boiling point, and low cost. Its narrow boiling range minimises losses, and its low benzene content minimises toxicity. These same properties also make hexane a desirable solvent and reaction medium in the manufacture of polyolefins, synthetic mbbers, and some pharmaceuticals. The solvent serves as catalyst carrier and, in some systems, assists in molecular weight regulation by precipitation of the polymer as it reaches a certain molecular size. However, most solution polymerization processes are fairly old it is likely that those processes will be replaced by more efficient nonsolvent processes in time. [Pg.406]

The ratio of a-lactose [10039-26-6] and P-lactose in dry milk and whey varies according to the speed and temperature of drying. An aqueous solution at equiHbrium at 25°C contains 35% a- and 63% -lactose. The latter is more soluble and sweeter than DL-lactose and is obtained by heating an 80% DL-lactose [63-42-3] solution above 93.5°C, foUowed by drying on a dmm or roUer dryer. Lactose is used for foods and pharmaceutical products. [Pg.370]

Pharmaceutical Industry. In the pharmaceutical industry, sterility of deionized water systems is maintained by using an ozone residual. The ozone residual concentration is maintained at >0.3 ppm ppm in the water recirculation loop. Prior to product compounding, the ozone residual is removed by contact with uvirradiaton for <1 s. Ozone also is used to oxidize pyrogens from distilled water destined for intravenous solutions. [Pg.502]


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See also in sourсe #XX -- [ Pg.140 ]




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