Resonance ionization spectrometry

From the 1980s onwards, dedicated setups (and acronyms) have been developed, e.g., SALI (Becker and Gillen, 1984), sputter initiated resonance ionization spectrometry (SIRIS) (Parks, 1990), surface analysis by resonant ionization of sputtered atoms (SARISA, Pellin et al., 1989), and the Chicago-Argonne resonance ionization mass analysis (CHARISMA, Ma et al., 1995). The recent proliferation of commercial time-of-flight (TOP) secondary ion mass spectrometry (SIMS) instruments stimulates their conversion into SALI setups. 

Every effort is made here to achieve the highest possible absolute power of detection. Microdistribution analysis represents the primary field of application for microprobe techniques based on beams of laser photons, electrons, or ions, including electron microprobe analysis (EPMA), electron energy-loss spectrometry (EELS), particle-induced X-ray spectrometry (PIXE), secondary ion mass spectrometry (SIMS), and laser vaporization (laser ablation). These are exploited in conjunction with optical atomic emission spectrometry and mass spectrometry, as well as various forms of laser spectrometry that are still under development, such as laser atomic ab.sorption spectrometry (LAAS), resonance ionization spectrometry (RIS). resonance ionization mass spectrometry (RIMS), laser-enhanced ionization (LEI) spectrometry, and laser-induced fluorescence (LIF) spectrometry [36]-[44],... 

In other articles in this section, a method of analysis is described called Secondary Ion Mass Spectrometry (SIMS), in which material is sputtered from a surface using an ion beam and the minor components that are ejected as positive or negative ions are analyzed by a mass spectrometer. Over the past few years, methods that post-ion-ize the major neutral components ejected from surfaces under ion-beam or laser bombardment have been introduced because of the improved quantitative aspects obtainable by analyzing the major ejected channel. These techniques include SALI, Sputter-Initiated Resonance Ionization Spectroscopy (SIRIS), and Sputtered Neutral Mass Spectrometry (SNMS) or electron-gas post-ionization. Post-ionization techniques for surface analysis have received widespread interest because of their increased sensitivity, compared to more traditional surface analysis techniques, such as X-Ray Photoelectron Spectroscopy (XPS) and Auger Electron Spectroscopy (AES), and their more reliable quantitation, compared to SIMS. 

Johnson SG, Fearey BL (1993) Spectroscopic study of thorium using continuous-wave resonance ionization mass-spectrometry with rrltraviolet ionization. Spectrochim Acta Part B 48 1065-1077 Knoll GF (1989) Radiation Detection and Measurement. J. Wiley and Sons, New York Kuss HM (1992) Applications of microwave digestion technique for elemental analyses. Fresenins J Anal Chem 343 788-793... 

Jensen P.K., Pasa-Tolic L., Anderson G. A., Horner J. A., Lipton M.S., Bruce J.E., and Smith R.D., Probing proteomes using capillary isolectric focusing-elec-trospray ionization Fourier transform ion cyclotron resonance mass spectrometry, Anal. Chem. 71, 2076, 1999. 

Wunschel, D. S. Fox, K. F. Bruce, J. E. Muddiman, D. C. Smith, R. D. Analysis of double-stranded polymerase chain reaction products from the Bacillus cereus group by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Comm. Mass Spectrom 1996,10, 29-35. 

Resonance Ionization Mass Spectrometry Reference Material... 

Leinweber, F.C., Schmid, D.G., Lubda, D., Wiesmuller, K., Jung, G., Tallarek, U. (2003). Silica-based monoliths for rapid peptide screening by capillary hquid chromatography hyphenated with electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun. Mass. Spectrom. 17, 1180-1188. 

Koide et al. [528,529] determined osmium in seawater by passing the water down an anion exchange resin column, followed by distillation of the osmium tetroxide and detection by resonance ionization mass spectrometry. 

K. Wendt, K. Blaum, B. A. Bushaw, C. Griming, R. Horn, G. Huber, J. V. Kratz, P. Kunz, P. Muller, W. Nortershauser, M. Nunnemann, G. Passler, A. Schmitt, N. Trautmann, and A. Waldek. Recent Developments in and Applications of Resonance Ionization Mass Spectrometry. Fresenius. J. Anal. Chem., 364(1999) 471-477. 

J. S. Sampson, A. M. Hawkridge, and D. C. Muddiman. Generation and Detection of Multiply-Charged Peptides and Proteins by Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. J. Am. Soc. Mass Spectrom., 17(2006) 1712-1716. 

M. E. Belov, M. V. Gorshkov, H. R. Udseth, G. A. Anderson, and R. D. Smith. Zeptomole-Sensitivity Electrospray Ionization-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Proteins. Anal. Chem., 72(2000) 2271-2279. 

Z. Wu, R.P. Rodgers and A.G. Marshall, Characterization of vegetable oils Detailed compositional fingerprints derived from electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry, J. Agric. Food Chem., 52 (2004) 5322-5328. 

Hughey, C.A. Hendrickson, C.L. Rodgers, R.P. Marshall, A.G. Elemental Composition Analysis of Processed and Unprocessed Diesel Fuel by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Energy Fuels 2001,15. 1186-1193. 

B. A. Properties and Performance of a Quadrapole Mass Filter Used for Resonance Ionization Mass Spectrometry. Int. J. Mass Spectrom. 1998,181, 67-87. 

Hofstadler, S. A., Swanek, E D., Gale, D. C., Ewing, A. G., and Smith, R. D. (1995). Capillary electrophoresis-electrospray ionization Eourier transform ion cyclotron resonance mass spectrometry for direct analysis of cellular proteins. Anal. Chem. 67, 1477—1480. 

RIMS See resonant ionization mass spectrometry. rimz or ar T em es ring org chem A closed loop of bonded atoms In a chemical structure, for example, benzene or cyclohexane. rir ... 

Akashi S., Takio K. Melittin-diacylphosphatidylcholine interaction examined by electrospray ionization fourier transform ion cyclotron resonance mass spectrometry. 

Note The acronyms used here are OSPED (optical spectroscopy in a pulsed electrical discharge), FAMS (flowing afterglow mass spectrometry), SIFT (selected ion flow tube), TRAPI (time-resolved atmospheric pressure ionization mass spectrometry), PHPMS (pulsed high-pressure ionization mass spectrometry), ICRMS (ion cyclotron resonance mass spectrometry), and ADO (averaged dipole orientation collision rate theory). 

N. J. Haskins, C. Eckers, A. J. Organ, M. F. Dunk and B. E. Winger, The use of electrospray ionization with Fourier transform ion cyclotron resonance mass spectrometry in the analysis of trace impurities in a drag substance. Rapid Communications in Mass Spectrometry, 1995,9(11), 1027-1030. 

Shen, Y. R, Zhao, R., Belov, M. E., Conrads, T. R, Anderson, G. A., Tang, K. Q., Pasa-Tolic, L., Veenstra, T. D., Lipton, M. S., Udseth, H. R., and Smith, R. D., Packed capillary reversed-phase liquid chromatography with high-performance electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for proteomics. Analytical Chemistry 73(8), 1766-1775, 2001. 

Resonance ionization mass spectrometry (RIMS) is much more efficient at getting ions into the detectors. First, atoms are removed from the sample surface with a pulsed laser, which can release the atoms thermally without ionizing them. Then, by using carefully tuned lasers, the element of interest in the resulting gas plume can be ionized at almost 100% efficiency, while other elements are not ionized at all. The ions are extracted into a time-of-flight... 

Resonance-ionization mass-spectrometry is still in the development stage in terms of its application to cosmochemistry. The Charisma instrument, which is operated by Argonne National Laboratories, uses multiple lasers to resonantly ionize only the elements of interest, which are then analyzed with a time-of-flight mass spectrometer. The Charisma instrument has made isotopic measurements of molybdenum, zirconium, strontium, ruthenium, barium and other elements in presolar grains. These measurements are made possible by the high ionization efficiency of the RIMS technique and its ability to completely eliminate isobaric interferences. Work is now underway to build a RIMS instrument that can be operated by an individual investigator in a university laboratory. If this succeeds, RIMS will play an increasing role in analysis of extraterrestrial materials. 

In 1974, Comarisov and Marshall60 developed Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS). This technique allows mass spectrometric measurements at ultrahigh mass resolution (R = 100000-1000000), which is higher than that of any other type of mass spectrometer and has the highest mass accuracy at attomole detection limits. FTICR-MS is applied today together with soft ionization techniques, such as nano ESI (electrospray ionization) or MALDI (matrix assisted laser/desorption ionization) sources. 

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