Promoter analysis

Wetzel MA, Steele AD, Eisenstein TK, Adler MW, Henderson EE, Rogers TJ (2000) Mu-opioid induction of monocyte chemoattractant protein-1, RANTES, and IFN-gamma-inducible protein-10 expression in human peripheral blood mononuclear cells. J Immunol 165 6519-6524 Widmer U, Manogue KR, Cerami A, Sherry B (1993) Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta, members of the chemokine superfamily of proinflammatory cytokines. J Immunol 150 4996-5012 Ye RD (2001) Regulation of nuclear factor kappaB activation by G-protein-coupled receptors. [Review] [136 refs]. J Leukoc Biol 70 839-848... 

Granulocyte differentiation acute promyelocytic leukemia PBMCs (in vivo) Cultured bone marrow mononuclear cells (in vitro) All-trans retinoic acid (ATRA) Promoter analysis of ATRA response genes suggest molecular mechanism underlying ATRA-induced granulocytic differentiation [30]... 

Research on FLAP has continued at a rapid pace, with gene cloning, promoter analysis and site-directed mutagenesis in progress [498,499], This promises to be an area of great interest in the future. 

Moreira, J.M. and Holmberg, S. (1998) Nucleosome structure of the yeast CHAl promoter analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators. EMBO J. 17, 6028-6038. 

Metz, B.A., Welters, P., Hoffman, H.J., Jensen, E.O., Schell, J. de Bruijn, F.J. (1988). Primary structure and promoter analysis of leghemoglobin gene of the stem nodulated tropical legume Sesbania rostrata conserved coding sequences, cis elements and trans-acting factors. Molecular and General Genetics 214, 181-91. 

Dode, L., De Greef, C., Mountian, I., Attard, M., Town, M. M., Casteels, R., and Wuytack, F., 1998, Structure of the human sarco/endoplasmic reticulum Ca2+-ATPase 3 gene. Promoter analysis and alternative splicing of the SERCA3 pre-mRNA. J Biol Chem, 273 13982—94. 

Promoter analysis and hormonal stimulation experiments allowed us to obtain insights into the mechanisms that regulate expression of the human kallikrein genes. In addition to KLK3 and KLK2, and more recently KLK10, no other kallikrein gene promoter has been functionally tested. 

While the primary structure of proteins and nucleic acids can be experimentally determined in a straight-forward manner, their higher-order structures are much more difficult to elucidate. In general, computational methods dealing with primary structure focus on interpretation of the structure-function, as in promoter analysis. By contrast computational methods working on higher-order structure instead focus on the prediction of structural details. Further, most techniques are limited to the prediction of RNA and protein structures—sugar-, fatty-add-, and DNA-structural prediction methods are in their infancy. 

Qiu P. Recent advances in computational promoter analysis in understanding the transcriptional regulatory network. Biochem Biophys Res Commun 2003 309 495-501. 

Steroids are a group of hormones with similar chemical structures that help to control growth, metabolism, development of sexual characteristics, and the ability to withstand the stress of illness and injury. Because of their legal use as medicaments or illegal use as growth promoters, analysis and positive identification of trace amounts... 

Au, H.C., and I.E. Scheffer (1998). Promoter analysis of the human succinate dehydrogenase iron-protein gene both nuclear respiratory factors NRF1 and NRF2 are required. Eur. J. Biochem 251 164-174. 

Further detailed promoter analysis suggestes that E2F responsiveness is mediated by more than one E2F element in the minimal promoter. Because only one weak affinity E2F1 complex at —117 was identified experimentally, we... 

Hu, Z. and Poulton, J.E. (1997) Sequencing, genomic organization and preliminary promoter analysis of black cherry (R)-(+)-mandelonitrile lyase gene. Plant Physiol, 115(4), 1359-69. 

Yang, Q., Grimmig, B. and Matern, U. (1998) Anthranilate N-hydroxycinnamoyl/ benzoyltransferase gene from carnation rapid elicitation of transcription and promoter analysis. Plant Mol. Biol, 38, 1201-14. 

L. Pardo, N. Pastor and H. Weinstein. Selective binding of the TATA box-binding protein to the TATA box-containing promoter analysis of structural and energetic factors. Biophys. J. 75 (1998) 2411-21. 

Kawaji, H., Kasukawa, T., Fukuda, S., et al. (2006) CAGE Basic/Analysis Databases the CAGE resource for comprehensive promoter analysis. Nucleic Acids Res. 34, D632-D636. 

Comparative Genomics-Based Orthologous Promoter Analysis Using the DoOP Database and the DoOPSearch Web Tool... 

Cartharius, K., Freeh, K., Grote, K., et al. (2005) Matlnspector and beyond promoter analysis based on transcription factor binding sites. Bioinformatics 21, 2933-2942. 

Takeuchi, Y., Yahagi, N., Nakagawa, Y., Matsuzaka, T., Shimizu, R., Sekiya, M., lizuka, Y., Ohashi, K., Gotoda, T., Yamamoto, M., et al. In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-lc expression. Biochem Biophys Res Commun 363 (2007) 329-335. 

Promoter analysis indicates a 39-bp core promoter, containing TATA and initiator elements that control transcription. Binding of the transcription... 

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