Mutants defective

Wallraff, E., Schleicher, M., Modersitzki. M Reiger, D., Isenberg, G., Gerish, G. (1986). Selection of Dictyostelium mutants defective in cytoskeletal protein Use of an antibody that binds to the ends of alpha-actinin rods. EMBO J. 5,61-67. 

Palese P, Tobita K, Ueda M, Compans RW (1974b) Characterization of temperature sensitive influenza virus mutants defective in neuraminidase. Virology 61 397 10 Pegg MS, von Itzstein M (1994) Slow-binding inhibition of sialidase from influenza virus, Biochem Mol Biol Int 32 851-858... 

In contrast, less effort has apparently been directed to the transport of xenobiotics, and there is an intrinsic difficulty that in contrast to organisms that utilize carbohydrates or amino acids, suitable mutants defective in the metabolism of the substrate may not be available. This limitation makes it impossible to determine directly whether active transport is involved. Although the genes encoding permeases have been described quite frequently, details of their mechanisms have been less well documented ... 

Finette BA, V Subramanian, DT Gibson (1984) Isolation and characterization of Pseudomonas putida PpFl mutants defective in the toluene dioxygenase enzyme system. J Bacteriol 160 1003-1009. 

Hassett DJ, HP Schweitzer, DE Ohman (1995) Pseudomonas aeruginosa sodA and sodB mutants defective in manganese- and iron-cofactored superoxide dismutase activity demonstrate the importance of the iron-cofactored form in aerobic metaholism. J Bacteriol 111 6330-6337. 

Prieto-Alamo, M.J., Abril, N. and Pueyo, C. (1993). Mutagenesis in Escherichia coli K-12 mutants defective in superoxide dismutase or catalase. Carcinogenesis 14, 237-244. 

Raths, S., Rohrer, J., Crausaz, F. and Riezman, H., 1993, Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae. J.Cell Biol., 120 55-65. 

Emoto, K., Kuge, O., Nishijima, M., and Umeda, M., 1999, Isolation ofa Chinese hamster ovary ceh mutant defective in intramitochondrial transport of phosphatidylserine. Proc. Natl. Acad. Sci. USA, 96 12400-12405. 

Esko, J.D., Wermuth, M.M., and Raetz, C.R., 1981, Thermolabile CDP-chohne synthetase in an animal ceh mutant defective in lecithin formation. J. Biol. Chem. 256 7388-7393 Esko, J.D., Nishijima, M., and Raetz, C.R., 1982, Animal cells dependent on exogenous phosphatidylchohne for membrane biogenesis. Proc. Natl. Acad. Sci. USA. 79 1698-1702 Exton, J. H., 1994, Phosphatidylchohne breakdown and signal transduction, Biochim. Biophys. Acta 1212 2642. 

Moreira, J.M. and Holmberg, S. (1998) Nucleosome structure of the yeast CHAl promoter analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators. EMBO J. 17, 6028-6038. 

Reed, S. I. The selection of S. cerevisiae mutants defective in the start of cell division. Genetics. 95 561-577.1980. 

Western, T.L. et al., Isolation and characterization of mutants defective in seed coat mucilage secretory cell development in Arabidopsis. Plant Physiol, 127, 998, 2001. 

The occurrence of this group of sugar nucleotides is limited mainly to the cells of Gram-negative bacteria. Those bacterial mutants defective in lipopolysaccharide synthesis are useful for preparative isolation of such esters, as the concentration of sugar nucleotides in normal cells is very low. 

Palase P, Tobita K, Ueda M, Compans RW. Characterization of temperature sensitive influenza virus mutants defective in neuraminidase. Virology 1974 61 397-410. 

Oosawa, K. Hess, J.R Simon, M.L Mutants defective in bacterial chemotaxis show modified protein phosphorylation. Cell, 53, 89-96 (1988)... 

Recent studies, using an Arabidopsis mutant defective in the xanthophyll cycle, point to a chlorophyllbinding protein PsbS, which participates in nonphoto-... 

The reduction of nitrite by Klebsiella pneumoniae gives 5% N20 and 95% NH4+. Mutants defective in the reduction of nitrite to ammonium ions produced dinitrogen monoxide at rates comparable to the parent strain. This suggests that the nitrite reductase giving N20 was distinct from that producing NH4+.1535... 

The biosynthesis of the LPS is initiated at the Lipid A portion of the molecule and proceeds toward the non-reducing terminus. Mutants defective in either the biosynthesis or the activation and transfer of most of the individual sugars are known... 

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