Potassium bicarbonate-citrate

K-Lor oral solution (potassium bicarbonate/citrate) M in glassful of OJ and drink... 

Metabolic acidosis and hyperchioremia Potassium depletion is rarely associated with metabolic acidosis and hyperchloremia. Replace with potassium bicarbonate, citrate, acetate, or gluconate. 

Brand Name(s) (potassium bicarbonate-citrate) Effer K, Klor-Con EF, K-Lyte, K-Lyte DS... 

Normal adult concentration of serum potassium is 3.5 mmol to 5.0 mmol or mEq per liter, with 4.5 mmol or mEq often used as a reference point 1 g of potassium acetate provides 10.26 mEq of potassium 1 g of potassium bicarbonate provides 10 mEq of potassium 1 g of potassium chloride provides 13.41 mEq of potassium 1 g of potassium citrate provides 9.26 mEq of potassium 1 g of potassium gluconate provides 4.27 mEq of potassium... 

Soluble, effervescent tablets are prepared by compression. In addition to active ingredients, they contain mixtures of acids (citric acid, tartaric acid) and sodium bicarbonate (NaHCOs) that release carbon dioxide when dissolved in water. The United States Pharmacopeia (USP) 24 includes the following seven monographs Acetaminophen for Effervescent Oral Solution Aspirin Effervescent Tablets for Oral Solution Potassium Bicarbonate Effervescent Tablets for Oral Solution Potassium Bicarbonate and Potassium Chloride for Effervescent Oral Solution Potassium Bicarbonate and Potassium Chloride Effervescent Tablets for Oral Solution Potassium and Sodium Bicarbonates and Citric Acid for Oral Solution and Potassium Chloride, Potassium Bicarbonate, and Potassium Citrate Effervescent Tablets for Oral Solution. ... 

Potassium citrate is prepared by adding either potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases. The resulting solution is then filtered and evaporated to dryness to obtain potassium citrate. 

Potassium triplex (potassium acetate, bicarbonate, citrate) Oral rarely used... 

Potassium bicarbonate/ potassium citrate K-Lyte (Bristol) 25 mEq bicarbonate/tablet 25 mEq tablet (effervescent) ... 

Supplements. Supplements of potassium in medicine are most widely used in conjunction with the most powerful classes of diuretics, which rid the body of sodium and water, but have the side effect of also causing potassium loss in urine. Potassium supplements are available as a number of different salts, including potassium chloride, citrate, gluconate, bicarbonate, aspartate, and orotate. °... 

Plating solution, chrome Potassium acid sulfate Potassum alum Potassum aluminum sulfate Potassium bicarbonate Potassium bichromate Potassium bifluoride Potassium bisulfate Potassium bisulfite Potassium bitartrate Potassium bromide Potassium carbonate Potassium chlorate Potassium chloride Potassium chromates Potassium citrate Potassium cyanate Silicone tetrachloride, dry Silicone tetrachloride, wet Silver bromide Silver chloride Silver cyanide Silver nitrate Silver sulfate Soap solutions Soda ash Sodium acetate Sodium benzoate Sodium bicarbonate Sodium bichromate Sodium bifluoride Sodium bisulfate Sodium bisulfide Sodium bisulfite Sodium borate Sodium bromate Sodium bromide Sodium carbonate... 

Pentasodium triphosphate Potassium acetate Potassium acid tartrate Potassium alum anhydrous Potassium bicarbonate Potassium bisulfate Potassium carbonate Potassium chloride Potassium citrate Potassium diacetate... 

Potassium dihydrogen citrate Potassium fumarate Potassium hydrogen malate Potassium hydroxide Potassium lactate Potassium malate Potassium phosphate Potassium phosphate dibasic Potassium phosphate tribasic Potassium polyphosphate Potassium sodium tartrate Potassium sodium tartrate tetrahydrate Potassium tripolyphosphate Sodium acetate anhydrous Sodium acetate trihydrate Sodium acid pyrophosphate Sodium aluminum phosphate acidic Sodium aluminum phosphate basic Sodium bicarbonate Sodium calcium polyphosphate Sodium carbonate Sodium citrate Sodium diacetate . Sodium fumarate Sodium hydrogen malate... 

Alkaline Copper Iodide Reagent. In 600 ml. of warm water are dissolved 81 g. of potassium citrate (KjCoHiO/.HiO), 70 g. of potassium bicarbonate, and 92 g. of potassium oxalate (K1C2O4.H2O). A solution of 25 g. of copper sulfate (CUSO4.-5H 0) is run into the bottom of the main solution with constant stirring. To the mixture a solution of 3.57 g. of potassium iodate and 50 g. of potassium iodide in 200 ml. of water is added. The whole is cooled and made up to 1 liter. 

Solutions that contain sodium citrate/citric acid (Shohl s solution and Bicitra) provide 1 mEq/L (1 mmol/L) each of sodium and bicarbonate. Polycitra is a sodium/potassium citrate solution that provides 2 mEq/L (2 mmol/L) of bicarbonate, but contains 1 mEq/L (1 mmol/L) each of sodium and potassium, which can promote hyperkalemia in patients with severe CKD. The citrate portion of these preparations is metabolized in the liver to bicarbonate, while the citric acid portion is metabolized to C02 and water, increasing tolerability compared to sodium bicarbonate. Sodium retention is also decreased with these preparations. However, these products are liquid preparations, which may not be palatable to some patients. Citrate can also promote aluminum toxicity by augmenting aluminum absorption in the GI tract. 

Urinary alkalinization- Urates tend to crystallize out of an acid urine therefore, a liberal fluid intake is recommended, as well as sufficient sodium bicarbonate (3 to 7.5 g/day) or potassium citrate (7.5 g/day) to maintain an alkaline urine continue alkalization until the serum uric acid level returns to normal limits and tophaceous deposits disappear. Thereafter, urinary alkalization and the restriction of purine-producing foods may be relaxed. 

Acetic, boric, and hydrochloric acids Potassium and sodium bicarbonate Potassium and sodium borate Potassium and sodium phosphate Potassium and sodium citrate... 

During initial therapy a fluid intake of at least 2 1/d should be ensured to prevent urate crystall-uria. If the uric acid load is high, consider rendering the urine alkaline with Potassium Citrate Mixture 12-24 g/d with water p.o. or sodium bicarbonate powder 5-10 g/d with water p.o., again to prevent uric acid crystal formation in the renal tract. Other adverse effects are mainly gastrointestinal sulfinpyrazone is contraindicated in peptic ulcer. 

The urine can be made alkaline by sodium bicarbonate i.v., or by potassium citrate by mouth. Sodium overload may exacerbate cardiac failure, and sodium or potassium excess are dangerous when renal function is impaired. 

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