Dibasic potassium phosphate

All chemicals were used as received. PDADMAC and PAMPS were obtained from Aldrich Chemical Co. (Milwaukee, WI). Diclofenac sodium, sodium sulfathiazole, labetalol HCl, propranolol HCl, verapamil HCl, and diltiazem HCl were purchased from Sigma Chemical (St. Louis, MO). Dextrose USP was obtained from Amend Co. (Irvinton, NJ). Water was distilled and deionized using a Nanopure purihcation system (Fischer Scientihc, Fair Lawn, NJ). Simulated intestinal fluid was prepared using a O.OIM phosphate buffer (sodium phosphate monobasic and potassium phosphate dibasic) at pH 7 and 5.5 with different amounts of NaCl to vary the ionic strength. Simulated gastric fluid (pH 1.5) was prepared with concentrated HCl with different amounts of NaCl to vary the ionic strength. 

Potassium phosphate, dibasic Potassium chloride Radiolite No. 600 Dowex... 

Bulk HPLC Dissolve in mobile phase SCX Acetonitrile-0.5 M potassium phosphate, dibasic adjust to pH 3.5 (55 45) 280 nm USP 23, ISTD-methylparaben, assay, GC [1000] HPLC [9,515,1001,1002] stability [511] [5]... 

Potassium Phosphate, Dibasic, occurs as a colorless or white, granular salt that is deliquescent when exposed to moist air. One gram is soluble in about 3 mL of water. It is insoluble in alcohol. The pH of a 1% solution is about 9. 

Fig. 2 Chromatographic comparison of protein elution profiles from PEZ and ZrP04 phases. Particles (4.5 pm) were packed in 50 mm X 4.6 mm i.d. eolumns. Mobile phase 30 min linear gradient from 50 to 500 mM potassium phosphate dibasic, pH 7.0 0.5 mL/min ambient temperature deteetion at 280 nm. Peaks 1—myoglobin, 2—lysozyme, 3— R-chymotrypsin, 4— ribonuclease A, 5—cytochrome c. (From Ref. [17].)...

Indole-3-acetic acid (Fig. 4.16) may be extracted from plant tissue after first homogenizing a 0.1-g sample and extracting the plant tissue with 75mAf potassium phosphate dibasic. After extraction, the pH is adjusted to 2.7 with 2.8 M phosphoric acid and the sample is dialyzed with 15 mL 0.1M potassium phosphate dibasic. The pH adjustment is necessary to protonate the acetic acid functionality for good retention on the C-18 sorbent. Use a trifunctional sorbent that is resistant to acid hydrolysis. 

Liposome samples (20 pL) in triplicate are dehydrated at 180°C for lOmin, then mixed and heated with 1.5mL of 3.33N H2S04 for 2h at the same temperature. Standards prepared from potassium phosphate dibasic in deionized water (16, 32, 64, 128, and 256nmol phosphate per tube in triplicate) are subjected concurrently to the same procedure. Note that inorganic phosphates will interfere with the... 

Addition of salts (e.g. potassium phosphate dibasic ) partitions an aqueous system containing 202 w/v polyethylene glycol < PEG) into two liquid phases a PEG enriched phase and a salt enriched phase. Proteins and polymers (e.g. DNA, albumin, immunoglobulins, alpha-1 antitrypsin, and PEG) distribute unevenly between the two phases. Partition coefficients (concentration in PEG phase / concentration in salt phase = K) are influenced by physical parameters, such as salt composition and concentration, pH (ion ratios) and temperature. Specific proteins (e.g. alpha-1 antitrypsin) exhibit low K values in a wide range of conditions. 

Monobasic potassium phosphate, dibasic sodium phosphate, sodium chloride, sucrose, mannitol, glycine Monobasic sodium phosphate, dibasic sodium phosphate, sucrose, polysorbate 80 Monobasic sodium phosphate, dibasic sodium phosphate, sodium chloride Monobasic sodium phosphate, dibasic sodium phosphate, sodium chloride, polysorbate 80 Histidine, glycine, mannitol... 

The solvents used were (a) HPLC grade methanol and acetonitrile (Fisher Scientific) (b) water, double-distilled and stored in glass. Inorganic salts and acid (ammonium sulfate, potassium phosphate monobasic, potassium phosphate dibasic and phosphoric acid, 85%) were analytical reagent grade (Malllnckrodt Chemical Works). 

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