Potassium gluconate

A patient is to receive 10 mEq of potassium gluconate four times a day for three days. The dose is a teaspoonful. 

Sugar-coated products have been marketed that contain KCl in a wax matrix (Slow-K and Kaon-Ct) and are purportedly slow- and controlled-release preparations. Available evidence indicates that these slow-release forms of KCl are occasionally capable of causing local tissue damage and therefore prol5ably should be used with caution for K+ supplementation. Solutions of potassium gluconate, like the tablets, also have been associated with intestinal ulceration. Microencapsulated KCl preparations Micro-K, K-Dur) that are neither enteric coated nor contained within a wax matrix appear to be superior to the wax matrix formulation. 

Normal adult concentration of serum potassium is 3.5 mmol to 5.0 mmol or mEq per liter, with 4.5 mmol or mEq often used as a reference point 1 g of potassium acetate provides 10.26 mEq of potassium 1 g of potassium bicarbonate provides 10 mEq of potassium 1 g of potassium chloride provides 13.41 mEq of potassium 1 g of potassium citrate provides 9.26 mEq of potassium 1 g of potassium gluconate provides 4.27 mEq of potassium... 

Standard Solution Similarly, prepare a solution containing 10 mg/mL of USP Potassium Gluconate Reference Standard in water. 

Potassium Gluconate occurs as a white or yellow-white, crystalline powder or granules. It is anhydrous or the monohydrate. It is freely soluble in water and in glycerin, slightly soluble in alcohol, and insoluble in ether. 

C. The infrared absorption spectrum of a mineral oil dispersion of the sample, previously dried, exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Potassium Gluconate Reference Standard. 

Forget the potassium supplement tablets that are available in many stores and pharmacies. On a bottle that I checked, one potassium gluconate tablet is listed as containing 550 mg. But read the information on the back label and you ll learn, as I did, that the tablet actually contains only 90 mg of actual potassium. You can get five times as much from a glass of orange juice. 

Gluconate, lactate, etc.—These terms refer to the anionic components of organic salts. For example, a positive potassium ion can be balanced in an electrolyte with a gluconate anion. If the liquid part were to be evaporated, the residue would be crystalline, potassium gluconate salt. 

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