Inflammation Hemorrhagic

Brassica alba (L.) Rabenh. B. juncea (L.) Czem. et Coss. Bai Jie Zi (Indian mustard) (seed, young shoot) Sinigrin, myrocin, sinapic acid, sinapine, potassium myronate, mustard oil, allyl isothiocyanate, behenic acid, erucic acid, benzyl isothiocyanate, eicosenic acid.48-50 Relieve bladder inflammation, hemorrhage, abscesses, lumbago, rheumatism, stomach disorders. 

Acute exposure to allyl alcohol causes liver and kidney damage. Allyl alcohol is classified as a periportal hepatotoxicant since it selectively damages the periportal region of the liver. Studies have shown that in adult rats, allyl alcohol produces a moderate to marked periportal necrosis with attendant inflammation, hemorrhage, and also decreases hepatic cytochrome P-450, benzphentamine N-demethyla-tion, and ethoxyresorufin 0-deethylation activities by 30%. In immature rats, it lowered both cytochrome P-450 activity (30%) and ethoxyresorufin O-deethylation (75%). Benzphetamine N-demethyl-ation was not significantly affected in immature rats. Intraperitoneal administration of 1.5 mmol kg of allyl alcohol to starved Swiss albino mice causes the development of hemolysis in 50% of the animals. Other toxic effects include renal necrosis, pulmonary edema, and central nervous system effects at higher dose levels. 

This book chapter presents competently the pathologic vitreous, including developmental abnormalities, inflammation, hemorrhage, effects of trauma, systemic diseases, and degenerative processes. 

Cyclophosphamide- or ifosfamide-induced damage to the bladder wall is caused primarily by their metabolite known as acrolein. Acrolein causes sloughing and inflammation of the bladder lining, leading to hemorrhage. This is most common when urine output is low because higher concentrations of acrolein come into contact with the bladder urothelium for longer periods of time. 

Plasma cell disorders Plasma cell disorders Inflammation-associated, familial Mediterranean fever Familial amyloidotic neuropathy, systemic senile amyloidosis Dialysis-associated amyloidosis Familial amyloidotic neuropathy, aortic amyloidosis Familial systemic amyloidosis Familial systemic amyloidosis Familial systemic amyloidosis Familial cerebral hemorrhage with amyloidosis Sporadic and familial Alzheimer s disease, familial cerebral hemorrhage with amyloidosis Spongiform encephalopathies C-cell thyroid tumors Insulinoma, type II diabetes Atrial amyloidosis Prolactinomas pituitary amyloidosis Iatrogenic amyloidosis Corneal amyloidosis ... 

A 45-year-old male on combination therapy for remission-maintenance acute lymphocytic leukemia develops suprapubic pain, dysuria, and hematuria. Evidence of hemorrhage and inflammation is apparent on cystoscopy of the urinary bladder. Which of the following agents most likely caused these findings ... 

Signs and Symptoms Initial symptoms include fever, generalized weakness, back pain, dizziness, and extreme weight loss. There may also be occasional nausea and vomiting. Fever may be biphasic. In some cases the illness can become hemorrhagic or cause inflammation of the brain leading to headaches, coma, or seizures. Can also cause inflammation of the eyes with an intolerance to light. Up to 10% of affected patients may have some permanent vision loss. 

Postmortem findings include small hemorrhages present in the internal organs, carcasses may be jaundiced, fluid in body cavities that frequently is blood-stained, intestinal inflammation, edematous and hemorrhagic gall bladder, and the liver may be necrotic. 

The low concentration group appeared normal and gained weight. At 1000 pg/L, liver necrosis and pulmonary hemorrhage. At 1800 pg/L, all had nonspecific inflammation of brain, heart, lung, liver, and kidney Nasal histopathology... 

Immediate inflammation of bronchial tubes and lungs Massive amounts of phlegm Hemorrhage Asphyxiation Dry land drowning... 

Hemorrhagic disease with no connective tissue problems Gum hyperplasia, inflammation, loss of teeth Skeletal deformity in children foot wound healing Anemia... 

In male rats the LC50 was 7 500 ppm for a single 8-hour exposure there was prostration followed by convulsive seizures at autopsy there was pulmonary hemorrhage. Rats exposed 6 hours/day, 5 days/week for 4 weeks to concentrations greater than 600 ppm had respiratory and ocular irritation and anemia. In another study rats repeatedly exposed to 665 ppm for 7 hours daily developed pulmonary inflammation, and there were minor changes in the liver and kidneys in some animals. ... 

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