Focal cerebral ischemia

Pignataro G, Gala R, Cuomo O et al (2004) Two sodium/ calcium exchanger gene products, NCX1 andNCX3, play a major role in the development of permanent focal cerebral ischemia. Stroke 35 2566-2570... 

Belayev L, Pinard E, Nallet H, Seylaz J, Liu Y, Riyamongkol P, Zhao W, Busto R, Ginsberg MD. Albumin therapy of transient focal cerebral ischemia in vivo analysis of dynamic microvascular responses. Stroke 2002 33 1077-1084. 

Marinov MB, Harbaugh KS, Hoopes PJ, Pikus HI, Harbaugh RE. Neuroprotective effects of preischemia intraarterial magnesium sulfate in reversible focal cerebral ischemia. J Neurosurg 1996 85 117-124. 

Du C, Hu R, Csemansky CA, Liu XZ, Hsu CY, Choi DW. Additive neuroprotective effects of dextrorphan and cycloheximide in rats subjected to transient focal cerebral ischemia. Brain Res 1996 718 233-236. 

Asahi M, Asahi K, Wang X, Lo EH. Reduction of tissue plasminogen activator-induced hemorrhage and brain injury by free radical spin trapping after embolic focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2000 20 452 57. 

Yang Y, Li Q, Shuaib A. Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate. Neuropharmacology 2000 39 881-888. 

Veltkamp R, Warner DS, Domoki F, Brinkhous AD, Toole JF, Busija DW. Hyperbaric oxygen decreases infarct size and behavioral deficit after transient focal cerebral ischemia in rats. Brain Res 2000 853 68-73. 

Schabitz WR, Schade H, Heiland S, Kollmar R, Bardutzky J, Henninger N, Muller H, Carl U, Toyokuni S, Sommer C, Schwab S. Neuroprotection by hyperbaric oxygenation after experimental focal cerebral ischemia monitored by mr-imaging. Stroke 2004 35 1175-1179. 

Kawamura S, Yasui N, Shrrasawa M, Fukasawa H. Therapeutic effects of h3fperbaric oxygenation on acute focal cerebral ischemia in rats. Surg Neurol 1990 34 101-106. 

Singhal AB, Wang X, Sumii T, Mori T, Lo EH. Effects of normobaric h3fperoxia in a rat model of focal cerebral ischemia-reperfusion. J Cereb Blood Flow Metab 2002 22 861 868. 

Liu S, Shi H, Liu W, Eumichi T, Timmins GS, Liu KJ. Interstitial po2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2004 24 343-349. 

Kim HY, Singhal AB, Lo EH. Normobaric hyperoxia extends the reperfusion window in focal cerebral ischemia. Ann Neurol 2005 57 571-575. 

Cole DJ, Matsumura JS, Drummond JC, Schell RM. Focal cerebral ischemia in rats effects of induced hypertension, during reperfusion, on cbf. J Cereb Blood Flow Metab 1992 12 64-69. 

Morimoto T, Ginsberg MD, Deitrich WD, Zhao W. Hyperthermia enhances spectrin breakdown in transient focal cerebral ischemia. Brain Res 1997 746(l-2) 43-51. 

Toung TJ, Hum PD, Traystman RJ, Bhardwaj A. Global brain water increases after experimental focal cerebral ischemia effect of hypertonic sahne. Crit Care Med 2002 30(3) 644-649. 

Buisson, A., Margaill, L, Callebert, J., Plotkine, M. and Boulu, R.G. (1993). Mechanism involved in the neuroprotective activity of a nitric oxide synthase inhibitor during focal cerebral ischemia. J. Neurochem. 61, 690-696. 

Imaizumi, S., Woolworth, V., Fishman, R.A. and Chan, P.H. (1989). Superoxide dismutase activities and their role in focal cerebral ischemia. J. Cereb. Blood Flow Metab. 9, S217. 

Meyer, F.B., Tally, P.W., Anderson, R.E., Sundt, T.M., Yaksh, T.L. and Sharbrough, F.W. (1987). Treatment of experimental focal cerebral ischemia with mannitol. Assessment by intracellular brain pH, cortical blood flow, and EEC. 

Gasche, Y., Copin, J. C., Sugawara, T., Fujimura, M. and Chan, P. H. Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. /. Cereb. Blood Plow Metab. 21 1393-1400,2001. 

Koketsu, N., Berlove, D. J., Moskowitz, M. A., Kowall, N. W., Caday, C. G. and Finklestein, S. P. Pretreatment with intraventricular basic fibroblast growth factor decreases infarct size following focal cerebral ischemia in rats. Ann. Neurol. 35 451-457,1994. 

Sheng, H., Bart, R. D., Oury, T. D., Pearlstein, R. D., Crapo, J. D. and Warner, D. S. Mice overexpressing extracellular superoxide dismutase have increased resistance to focal cerebral ischemia. Neuroscience 88 185-191,1999. 

Huang SS, Tsai SK, Chih CL, Chiang LY, Hsieh HM, Teng CM, Tsai MC (2001)Neuioprotective effect of hexasulfobutylated C60 on rats subjected to focal cerebral ischemia. Free Radic. Biol. Med. 30 643-649. 

O Neill, M., Rodent models of focal cerebral ischemia, in Current Protocols in Neuroscience, Crawley, J., Gerfen C., Rogawski, M., Sibley, D., Skolnick, P. and Wray, S., Eds., Wiley, New York, 1998, chap. 9. 

Rajanikant, G. K., Zemke, D., Senut, M. C., Frenzel, M. B., Chen, A. F., Gupta, R., and Majid, A. (2007). Carnosine is neuroprotective against permanent focal cerebral ischemia in mice. Stroke 38,3023-3031. 

Pin JP, Parmentier ML, Joly C, et al (1998) Coupling of metabotropic glutamate receptors to G-proteins differences from and similarities with other G-protein-coupled receptors. In Moroni F, Nicoletti F, PeUegrini-Giampietro DE (eds) Metabotropic glutamate receptors and brain function. Portland Press, Colchester, pp 9-18 Pitsikas N, BrambiUa A, Besozzi C, et al (2001) Effects of cerestat and NBQX on functional and morphological outcomes in rat focal cerebral ischemia. Pharmacol Biochem Behav 68 443-447... 

Fujimura M, Moiita-Fujimura Y, Narasimhan P, Copin J, Kawase M, Chan P (1999) Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke... 

Nowicki, J. P., Duval, D., Poignet, H., and Scatton, B. (1991). Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse. Eur. J. Pharmacol. 204, 339-340. 

Impairment of membrane-bound Na,K-ATPase, which is responsible for maintaining and restoring membrane potential, and an increased level of malondialdehyde (MDA), which is a known as an index of lipid peroxidation, are seen after unilateral focal cerebral ischemia in the mouse. Pretreatment with EGb (100 mg/kg/day, p.o. for 10 days) preserves the Na,K-ATPase activity during cerebral ischemia and prevents the increased MDA levels caused by cerebral... 

Zhang, R.L., Zhang, Z.G., Zhang, L., Chopp, M. (2001). Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neurosci, 105, 33-41. 

Jin, K., Sun, Y., Xie, L., Childs, J., , X.O., Greenberg, D.A. (2004). Post-ischemic administration of heparin-binding epidermal growth factor-like growth factor (HB-EGF) reduces infarct size and modifies neurogenesis after focal cerebral ischemia in the rat. J... 

Tsai TH, Chen SL, Xiao X, Chiang YH, et al. 2006. Gene therapy of focal cerebral ischemia using defective recombinant adeno-associated virus vectors. Front Biosci. 11 2061-2070. 

Zhang J. P. and Sun G. Y. (1995). Free fatty acids, neutral glycerides, and phosphoglycerides in transient focal cerebral ischemia. J. Neurochem. 64 1688-1695. 

Paradis E., Clavel S., Julien P., Murthy M. R. V., de Bilbao F., Arsenijevic D., Giannakopoulos P., Vallet P., and Richard D. (2004). Lipoprotein lipase and endothelial lipase expression in mouse brain regional distribution and selective induction following kainic acid-induced lesion and focal cerebral ischemia. Neurobiol. Dis. 15 312-325. 

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