Facility planning processes

The retention of experienced and knowledgeable personnel during facility operation and closure is an important management issue. Personnel staffing and retention plans need to be addressed early in the facility planning process. Implementation of a suitable personnel retention, transfer, and release program is essential to the successful closure of JACADS. The Army s contractor for JACADS has recognized this issue and has developed a staff retention plan. 

KEY POINTS OF INFLUENCE CHECKLIST FOR MEDICAL TECHNOLOGY INPUT INTO THE HEALTH CARE FACILITIES PLANNING PROCESS 38.19... 

While you may wish to defer a firm decision about where, specifically, to start rolling out the system until the pilot test is completed, it s wise to consider a number of options as part of the planning process. The priorities you identified in Chapter 5 (both facilities and elements) provide useful guidance similarly, the implementation strategy you have adopted (companywide, facility-specific, or hybrid) will affect these decisions. 

The planning processes described herein were traditional in nature, with little variation from year to year. Growth was steady, equipment technology advancements were available for the conditions expected, and while utility facilities were capital-intensive, a regulated guaranteed return on investment resulted in adequate financing capital. The utility planner had a vision of the future with acceptable accuracy. 

To get a better idea of the complexity of a real application scenario in these industries it makes sense to, once, exemplarily depict the planning processes in a typical production of active pharmaceutical ingredients (API production). Most pharmaceutical companies are looking at planning scenarios in which several hundred individual resources or facilities have to be accounted for, with demands and orders for some thousand final products. The planning horizon is often set to 2-5 years. Next to single equipment, there are facility pools, with one pool consisting of several individual units. 

The test plan that was executed at Holston Army Ammunition Plant (HAAP) demonstrated that the hydrolysis process for the energetic materials of interest successfully destroyed more than 99.7 percent of the energetics treated. Over 9,500 pounds of energetic materials were destroyed while encountering only the types of problems normally expected during the implementation of a new facility and process. The suite of tests performed at Los Alamos National Laboratory (LANL) and at HAAP covered a range of reaction temperatures and caustic concentrations. Under all these conditions, the destruction of energetics was carried out safely and effectively. 

Type II industrial systems represent a transitional stage where resource recovery becomes more integral to the workings of the industrial systems, but does not satisfy its requirements for resources. Manufacturing processes and environmental processes are integrated at least partially. Whole facility planning is at least partially implemented. 

Recommendation 2. The end state, end use, and stewardship issues pertaining to closure of any chemical agent disposal facility should be resolved early so that planning can proceed on an assured rather than an assumed basis. If possible, facility end uses should be included in the RCRA operating permit. If end use and end state cannot be defined early in the planning process, risk assessments and cost and schedule estimates for alternative end states and uses should be prepared. 

Bunch, P.R., Rowe, R.L., and Zentner, M.G. (1998) Large scale multi-facility planning using mathematical programming methods. AIChE Symposium Series, Proceedings of the Third International Conference of the Foundations of Computer-Aided Process Operations. Snowbird, Utah, USA, July 5-10, American Institute of Chemical Engineering, 94, p. 249. 

To facilitate adoption or approval of a PAT process, manufacturers may request a preoperational review of a PAT manufacturing facility and process by the PAT team by contacting the FDA Process Analytical Technology Team at PAT cder.fda. gov. ft should be noted that when certain PAT implementation plans neither affect the current process nor require a change in specifications, several options can be considered. Manufacturers should evaluate and discuss with the agency the most appropriate option for their situation. 

A review of facility and process information should be conducted in order to identify what is already known, provide information on the potential cause(s) and source(s) of toxicity, and help design a comprehensive TRE study (U.S. EPA, 1989 1999). All TRE team members must have a clear understanding of how the facility/process is designed and operated. However, much of this information should already be available as part of the Toxicity Prevention/Response Plan (see Section 4.1). It is also useful to document facility and ETP operations during collection of toxicity samples. If a toxic sample is observed, this information could lead to a... 

At the Pine Bluff Chemical Agent Disposal Facility (PBCDF), process knowledge, quality assurance data, and analytical data are used to make waste characterization decisions. Under the PBCDF RCRA permit, the term chemical agent free refers to contaminated or potentially contaminated solid materials that have been tested per the PBCDF waste analysis plan and found to be below the WCL or to have been thermally treated for 15 minutes at 1000°F. Under the waste analysis plan, waste may be shipped off-facility for treatment and/or disposal only if... 

An appropriate design team will demonstrate expertise in contamination control philosophies, space planning, code compliance, and mechanical and electrical design and will be familiar with materials of construction currently being used in pharmaceutical projects. It is frequently helpful to include a member of the construction team in the front-end planning effort to advise on constructibility of the facility being planned. Unrealistic construction schedules will be avoided and field rework will be minimized if appropriate attention is paid to the construction phase early in the planning process. 

Marked items marked are considered minimum data required for a HAZOP or What-If review to occur. This data basically contains the layout (plot plan) of the facility, the process design (P ID and process description) and how it will be controlled during an emergency (SAFE chart and fire protection plant). With this information the "experts" can understand the design and operating principles of the facility. Since the emergency isolation, depressurization and fire protection features are provided, it can be readily deduced how the facility will fare from a catastrophic incident. 

This paper describes the MIRADCOM Propulsion Facility Plan, the work flow process, the safety factors that must be considered and the primary organizations that assist in insuring that hazards are kept to an absolute minimum. Safety considerations become a consideration at the initiation of a concept and is a constant partner until the missile is phased out of the inventory. It is only by such constant attention that operations with such materials and devices can be performed without incurring disaster. 

The implementation of our EHS Management System has required each facility, business unit, and subsidiary to understand and address their EHS issues through an EHS planning process. This process, when integrated into the business strategic planning process, provides better management of business EHS risks and identifies new business opportunities. 

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