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Conjugated diene

Oxygenation of 1,3-dienes. Conjugated dienes can undergo an efficient... [Pg.249]

Buta-1,3-diene (conjugated alternating double and single bonds)... [Pg.280]

The double bonds in a conjugated diene are hydroborated separately, that is, there is no 1,4 addition. However, it is not easy to hydroborate just one of a conjugated system, since conjugated double bonds are less reactive than isolated ones. Thexylborane °(48) is particularly useful for achieving the cyclic hydroboration of dienes, conjugated or nonconjugated, as in the formation of 53." ... [Pg.1015]

The work of Sharp and his many co-workers at Edinburgh cannot be underestimated. In a more recent communication they have extended the scope of his cyclisation of diene-conjugated nitrile ylides to triene homologues <96CC2739>. Thus cyclisation of the triene 21 afforded the cyclopropa[c]isoquinoline 22, which on heating gave a mixture of 23 and 24. The isomeric triene 25 also gave 24 as the sole product (Scheme 4). In this instance the intermediate cyclopropane could not be isolated. [Pg.321]

Second-derivative spectrophotometry has been used to monitor the time-dependent production of cis,tmns-(Xmax 242 nm) and trans, tram- (Xmax 232 nm) diene conjugates of microsomal PUFAs following the exposure of rats to carbon tetrachloride (CCU) (Corongui et al., 1986). These signals have been postulated to be derived from mixtures of peroxidized substrates. Previous studies using chemical model systems have established that autoxidation of linolenic or arachidonic acid results in the production of cis, trans- and tmns, trawr-conjugated diene... [Pg.14]

Shaw, S., Rubin, K.P. and Lieber, C.S. (1983). Depressed hepatic glutathione and increased diene conjugation in alcoholic liver disease. Dig. Dis. Sci. 28, 585-587. [Pg.171]

Speisky, H., Bunou, D., Orrego, H. and Israel, Y. (1985). Lack of changes in diene conjugate levels following ethanol-induced glutathione depletion or hepatic necrosis. Res. Commun. Chem. Pathol. Pharmacol. 48, 77-90. [Pg.171]

TBA, thiobarbituric acid reactivity DCs, diene conjugates MA, microangiopathy LP, lipid peroxides DM, diabetic patients C, controls HDL, high-density lipoprotein. [Pg.185]

Collier, A., Jackson, M., Dawkes, R.M., Bell, D. and Clarke, B.F. (1988). Reduced free radical activity detected by decreased diene conjugates in insulin-dependent diabetic patients. Diabetic Med. 5, 747-749. [Pg.195]

Thompson, S. and Smith, M.T. (1985). Measurement of the diene conjugated from of linoleic acid in plasma by high performance liquid chromatography. A questionable non-invasive assay of free radical activity. Chem. Biol. Interactions 55, 357-366. [Pg.198]

Oxidative stress Lipid oxidation Oxygen absorption Manometric, polarographic Diene conjugation HPLC, spectrophotometry (234 nm) Lipid hydroperoxides HPLC, GC-MS, chemiluminescence, spectrophotometry Iodine liberation Titration Thiocyanate Spectrophotometry (500 nm) Hydrocarbons GC Cytotoxic aldehydes LPO-586, HPLC, GC, GC-MS Hexanal and related end products Sensory, physicochemical, Cu(II) induction method, GC TBARS Spectrophotometry (532-535 nm), HPLC Rancimat Conductivity F2-iP GC/MS, HPLC/MS, immunoassays... [Pg.272]

Lipid peroxidation is probably the most studied oxidative process in biological systems. At present, Medline cites about 30,000 publications on lipid peroxidation, but the total number of studies must be much more because Medline does not include publications before 1970. Most of the earlier studies are in vitro studies, in which lipid peroxidation is carried out in lipid suspensions, cellular organelles (mitochondria and microsomes), or cells and initiated by simple chemical free radical-produced systems (the Fenton reaction, ferrous ions + ascorbate, carbon tetrachloride, etc). In these in vitro experiments reaction products (mainly, malon-dialdehyde (MDA), lipid hydroperoxides, and diene conjugates) were analyzed by physicochemical methods (optical spectroscopy and later on, HPLC and EPR spectroscopies). These studies gave the important information concerning the mechanism of lipid peroxidation, the structures of reaction products, etc. [Pg.773]

To illustrate the importance of vicinal connectivity of conjugating units, we consider two dienes in non-vicinal relationships 1,5-hexadiene, 9, and allene, 10. As shown in Table 3.19, the direct diene conjugations are negligible in both species, on account of spatial separation in 9 and symmetry-imposed orthogonality of the two pi planes in 10. Consistently with the essential absence of conjugation, the unsaturated C—C bonds of 9 and 10 have calculated bond orders characteristic of ethylene or other unconjugated systems and the ficc NLMOs have essentially localized character ... [Pg.193]

The content of the products of lipid peroxidation (LPO) was determined after 1 h of incubation of the cells in a buffer A at 37 °C. Aliquot of cell suspension (100 pg protein) was treated with heptane/isopropyl alcohol mixture at the ratio of 1 1. The content of Schiff bases in heptane phase was analyzed on fluorimeter RF-510, Shimadzu (Japan) at iexit = 360 nm and Xgms = 420 nm (Kolesova et al., 1984). The content of diene conjugates was determined by spectrophotometry (Gavrilov et al., 1988) at the wavelength of X = 245 nm using spectrophotometer Scinco (Germany). [Pg.126]

Taking into account that ROS produced by irradiated fullerenes C60 may act only in the radius of their short diffusion existence, one may suppose that cytotoxic effect is determined by the interaction of fullerene C60 with the surface of cells and initiation of chain reactions of free radical peroxidation in membranes. That is why the influence of photoexcited fullerene C60 on the course of LPO process was studied and evaluated by the content of generated primary (diene conjugates) and final (Schiff bases) products. The content of diene conjugates in thymocytes was 17.7 4.2, inEAC cells was 21.1 1.3, andinL1210 was 12.8 3.1 nM/mg protein, and Schiff bases -56 7.9,46.5 4.5, and 36.6 4.6 rel. units/mg protein, respectively, and did not alter during 1 h incubation of the cells. [Pg.129]

In the case of photoexcited fullerenes C60 and fullerene C60-containing composites in incubation medium of thymocytes, the indexes of LPO did not alter compared to the control too (Fig. 6.2A). Upon incubation of EAC cells in the presence of photoexcited samples of fullerenes, the decrease in the content of diene conjugates by 35% in the presence of fullerene C60 and by 20% in the presence of fullerene C60-composite-1 and fullerene C60-composite-2 was observed (Fig. 6.2B). The presence of photoexcited samples of fullerenes in the suspension of L1210 cells influenced LPO indexes only in the presence of fullerene C60-composite-2, when the content of diene conjugates increased by 35% (Fig 6.2C). [Pg.129]

Fig. 6.2 Content of diene conjugates (% from control) in thymocytes (A), EAC (B), and L1210 cells (C) after 1 h of incubation in the presence of photoexcited samples of fullerenes (1 - fullerene C60, 2 - C60-composite-l, 3 - C60-composite-2). P < 0.05 compared to the control... Fig. 6.2 Content of diene conjugates (% from control) in thymocytes (A), EAC (B), and L1210 cells (C) after 1 h of incubation in the presence of photoexcited samples of fullerenes (1 - fullerene C60, 2 - C60-composite-l, 3 - C60-composite-2). P < 0.05 compared to the control...
Simultaneous decrease in the content of diene conjugates and increase in the content of Schiff bases evidence the quick shift of pro-/antioxidant equilibrium, generation of reactive radicals, and damage of cell membranes in EAC cells, because Schiff bases, generated as a consequence of interaction of malonic dialdehyde with aminogroups of phospholipids and proteins, are highly reactive compounds causing polycondensation of molecules and formation of intermolecular bonds. [Pg.130]

It has been shown that the influence of photoexcited fullerene C60 on the processes of free-radical oxidation depends on the type of the cell and on the composition of composite. So, in thymocytes in the presence of photoexcited fullerene C60 as well as fullerene C60-containing composites, the content of primary and final LPO products did not alter compared to the control. In malignant cells the intensification of LPO processes was registered, and its level depends on the type of cells. So, in thymocytes in the presence of photoexcited fullerene C60 in suspension of EAC cells the decrease in the content of diene conjugates simultaneously with the increase in the... [Pg.130]

Gavrilov VB, Gavrilova AR, Khmara NF (1988) Measurement of diene conjugants in the plasma blood by UV absorption of heptane and isopropanole extracts. Russian Faboratomoe Delo. 2 60-63. [Pg.138]

Moody DA. 1992. Effect of phenobarbital treatment on carbon tetrachloride- mediated cytochrome P-450 loss and diene conjugate formation. Toxicol Lett 61 213-224. [Pg.175]


See other pages where Conjugated diene is mentioned: [Pg.182]    [Pg.51]    [Pg.923]    [Pg.522]    [Pg.923]    [Pg.36]    [Pg.1294]    [Pg.155]    [Pg.176]    [Pg.40]    [Pg.87]    [Pg.154]    [Pg.180]    [Pg.184]    [Pg.184]    [Pg.185]    [Pg.186]    [Pg.197]    [Pg.273]    [Pg.273]    [Pg.274]    [Pg.773]    [Pg.183]    [Pg.182]    [Pg.19]    [Pg.90]    [Pg.1470]   
See also in sourсe #XX -- [ Pg.58 , Pg.74 ]

See also in sourсe #XX -- [ Pg.58 , Pg.74 ]




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Addition of Amines to Conjugated Dienes

Addition of Hydrogen Halides to Conjugated Dienes

Addition reactions diene conjugation

Addition reactions of conjugated dienes

Addition reactions to conjugated dienes

Addition reactions, of conjugated diene

Addition to a Conjugated Diene

Alkene conjugated diene

Alkynes, conjugated dienes

Alkynes, conjugated dienes hydrometalation

Allenes diene conjugation

Allyl carbonates conjugated diene preparation

Allylic compounds conjugated diene preparation

Aziridination of Conjugated Dienes

Baseline diene conjugation

Bonding conjugated dienes

Bonding in conjugated dienes

Bromination conjugated dienes

Bromination of conjugated dienes

Carbocations conjugated dienes

Carbometallation conjugated dienes

Carbon Conjugated-dienes

Carbon number conjugated dienes

Carbon-oxygen bonds diene conjugation, allylic intermediates

Carboxylation of conjugated dienes

Catalyzed Hydrogenation of Alkynes and Conjugated Dienes

Chlorine to conjugated dienes

Classes of Dienes Conjugated and Otherwise

Cobalt conjugated dienes

Cobalt, hydrogenation conjugated dienes

Complexes Derived from Conjugated Dienes

Conjugate 1,3 dienes

Conjugate 1,3 dienes

Conjugate addition Conjugated dienes

Conjugate addition dienes

Conjugated Diene Monomers

Conjugated Diene Systems

Conjugated Dienes and Ultraviolet Light

Conjugated Dienes and Ultraviolet Spectroscopy

Conjugated Dienes. Electrophilic and Radical Addition

Conjugated acyclic dienes

Conjugated diene 1,2-addition reactions

Conjugated diene Diels-Alder reactions

Conjugated diene allylic carbocations from

Conjugated diene bond lengths

Conjugated diene butyl

Conjugated diene complexes

Conjugated diene complexes 13C NMR spectra

Conjugated diene complexes Diels-Alder reactions

Conjugated diene complexes H NMR spectra

Conjugated diene complexes NMR chemical shifts for

Conjugated diene complexes NMR spectra of, in solution

Conjugated diene complexes Z-isomerization

Conjugated diene complexes acyclic

Conjugated diene complexes cis/trans interconversion

Conjugated diene complexes crystal structure

Conjugated diene complexes cyclic

Conjugated diene complexes cycloaddition

Conjugated diene complexes decomplexation

Conjugated diene complexes deprotonation

Conjugated diene complexes dimerization

Conjugated diene complexes electrocyclic ring closure

Conjugated diene complexes electrophilic additions

Conjugated diene complexes epoxidation

Conjugated diene complexes fluxional behaviour

Conjugated diene complexes halogenation

Conjugated diene complexes hydroacylation of, ruthenium-catalysed

Conjugated diene complexes hydrocyanation

Conjugated diene complexes hydrogenation

Conjugated diene complexes in stereoselective synthesis

Conjugated diene complexes insertion reactions

Conjugated diene complexes isomerization

Conjugated diene complexes nucleophilic additions

Conjugated diene complexes of Cr, Mo and

Conjugated diene complexes of Mn and

Conjugated diene complexes of Nb and

Conjugated diene complexes of Rh and

Conjugated diene complexes of Ru and

Conjugated diene complexes of Ti, Zr and

Conjugated diene complexes of bromine

Conjugated diene complexes of carbenium ions

Conjugated diene complexes of carboxylic acids

Conjugated diene complexes of chlorine

Conjugated diene complexes of fluorine

Conjugated diene complexes of halogen azides

Conjugated diene complexes of hydrochloric acid

Conjugated diene complexes of hydrogen nucleophiles

Conjugated diene complexes of hydrogen sulphide

Conjugated diene complexes of iodine

Conjugated diene complexes of mercury compounds

Conjugated diene complexes of nitrogen nucleophiles

Conjugated diene complexes of oxygen nucleophiles

Conjugated diene complexes of selenenyl compounds

Conjugated diene complexes of selenium nucleophiles

Conjugated diene complexes of sulphenyl compounds

Conjugated diene complexes of sulphur nucleophiles

Conjugated diene complexes oxidation

Conjugated diene complexes phenylsulphonylmercuration

Conjugated diene complexes photopericyclic reactions

Conjugated diene complexes protonation

Conjugated diene complexes reactions with carbon electrophiles

Conjugated diene complexes rearrangement

Conjugated diene complexes reduction

Conjugated diene complexes synthesis

Conjugated diene complexes synthesis/isomerization

Conjugated diene electrocyclic reactions

Conjugated diene electrophilic addition reactions

Conjugated diene electrostatic potential map

Conjugated diene heats of hydrogenation

Conjugated diene hydrogenation

Conjugated diene insertion reactions

Conjugated diene molecular orbitals

Conjugated diene polymerisation

Conjugated diene polymerisation monomer coordination

Conjugated diene polymers

Conjugated diene reaction with

Conjugated diene reaction with HBr

Conjugated diene stability

Conjugated diene synthesis

Conjugated diene system, type

Conjugated diene, 1,2-addition

Conjugated diene, 1,2-addition allylic carbocations from

Conjugated diene, 1,2-addition electrocyclic reactions

Conjugated diene, 1,2-addition molecular orbitals

Conjugated diene, 1,2-addition polymers

Conjugated diene, 1,2-addition reaction with

Conjugated diene, 1,2-addition stability

Conjugated diene, 1,2-addition synthesis

Conjugated dienes , measurement

Conjugated dienes , measurement Lipid stability measurements

Conjugated dienes 1,4-elimination

Conjugated dienes 4+4]photocycloaddition

Conjugated dienes Cope rearrangement

Conjugated dienes Subject

Conjugated dienes activation

Conjugated dienes addition reactions

Conjugated dienes anodic oxidation

Conjugated dienes bond lengths

Conjugated dienes butadiene

Conjugated dienes catalysts

Conjugated dienes chirality

Conjugated dienes chromium-catalyzed

Conjugated dienes conformation

Conjugated dienes coordination polymerisation

Conjugated dienes copolymerisation

Conjugated dienes coupling reactions

Conjugated dienes cyclic

Conjugated dienes cyclic, selective hydrogenation

Conjugated dienes cyclization

Conjugated dienes cycloaddition

Conjugated dienes defined

Conjugated dienes definition

Conjugated dienes difunctionalization

Conjugated dienes electrophilic

Conjugated dienes electrophilic additions

Conjugated dienes electrophilic attack

Conjugated dienes epoxidation

Conjugated dienes from alkynes

Conjugated dienes from allenes

Conjugated dienes from arenes

Conjugated dienes from cyclopropanes

Conjugated dienes from heterocycles

Conjugated dienes halogenation

Conjugated dienes heteroannular

Conjugated dienes homoannular

Conjugated dienes hydrogenation

Conjugated dienes hydrogenolysis

Conjugated dienes hydrozirconation

Conjugated dienes insertion reactions

Conjugated dienes interesting examples

Conjugated dienes interesting/important

Conjugated dienes linear

Conjugated dienes metallation

Conjugated dienes metathesis

Conjugated dienes molecular orbitals

Conjugated dienes numbering carbon atoms

Conjugated dienes olefins

Conjugated dienes oligomerization

Conjugated dienes overview

Conjugated dienes oxidation

Conjugated dienes oxidative

Conjugated dienes oxygenations

Conjugated dienes palladium-catalysed

Conjugated dienes palladium-catalyzed

Conjugated dienes photochemical

Conjugated dienes photodimerization

Conjugated dienes polymerisation mechanism

Conjugated dienes preparation

Conjugated dienes product

Conjugated dienes radical addition

Conjugated dienes reactivity

Conjugated dienes rearrangement

Conjugated dienes reductive

Conjugated dienes regioselectivity

Conjugated dienes resonance forms

Conjugated dienes rhodium-catalyzed

Conjugated dienes selective

Conjugated dienes sigmatropic shifts

Conjugated dienes stereoisomers

Conjugated dienes structure

Conjugated dienes synthesis

Conjugated dienes telomerization

Conjugated dienes thermochemistry

Conjugated dienes value , secondary

Conjugated dienes value , secondary oxidation products

Conjugated dienes with singlet oxygen

Conjugated dienes, additions

Conjugated dienes, alkenes

Conjugated dienes, characteristic reaction

Conjugated dienes, determination

Conjugated dienes, formation

Conjugated dienes, hydrosilylation

Conjugated dienes, reaction

Conjugated dienes, reaction with borane

Conjugated dienes, stability

Conjugated systems 1,3-dienes

Conjugation Dienes, conjugated)

Conjugation Dienes, conjugated)

Conjugation, Resonance, and Dienes

Coordination polymerization conjugated dienes

Cross-conjugated diene

Cross-coupling reactions 1-alkenylboron. conjugated diene synthesis

Cross-coupling reactions conjugated diene synthesis

Cycloaddition of conjugated dienes

Cycloaddition reactions conjugated dienes

Cycloaddition to Conjugated Dienes The Diels-Alder Reaction

Cycloaddition to conjugated dienes

Cycloolefin/conjugated diene

Cyclopolymerization of conjugated dienes

Diels-Alder reaction conjugated dienes

Diels-Alder reactions conjugated diene synthesis

Diene conjugates

Diene non-conjugated

Dienes and the Allyl System 2p Orbitals in Conjugation

Dienes conjugated

Dienes conjugated

Dienes conjugated polymerization

Dienes conjugated, hydroamination

Dienes cross-conjugated—

Dienes non-conjugated—

Dienes, conjugated Friedel-Crafts reaction

Dienes, conjugated acylation

Dienes, conjugated metal atoms

Dienes, conjugated reaction with

Dienes, hydroformylation conjugated

Difunctionalization of Conjugated Dienes

Dioxygenation conjugated dienes

Dissolving metals conjugated dienes

Double bond number, conjugated dienes

Electrocyclic Reactions of Conjugated Dienes and Trienes

Electrocyclizations diene-conjugated ylides

Electron delocalization conjugated dienes

Electron delocalization in conjugated dienes

Electrophilic Additions to Conjugated Dienes Allylic Carbocations

Electrophilic Additions to Conjugated Dienes Allylic arbocations

Electrophilic Attack on Conjugated Dienes 1,4 Addition

Electrophilic Attack on Conjugated Dienes Kinetic and Thermodynamic Control

Electrophilic addition reactions of conjugated dienes

Electrophilic addition to conjugated dienes

Electrophilic attack on conjugated dienes

Elimination to Form Conjugated Dienes

Enantioselectivity conjugated diene reactions

Enchainment conjugated dienes

Endoperoxides from conjugated dienes

Epoxidation conjugated diene

Epoxidation of conjugated dienes

Ethylene-propylene, conjugated diene rubber

Ethylene/propylene/non-conjugated diene

Fatty acids conjugated dienes value

G Polyfluorinated conjugated dienes

Grignard reagents conjugated dienes

Heteroannular conjugated diene

Heteroatomic nucleophiles diene conjugation

Homoannular conjugated diene

Homopolymers of Conjugated Dienes

Hydroamination of conjugated dienes

Hydrocarboxylation conjugated dienes

Hydroformylation of conjugated dienes

Hydrogen availability selective, conjugated dienes

Hydrogen bromide conjugated dienes

Hydrogen bromide to conjugated dienes

Hydrogen chloride conjugated dienes

Hydrogen chloride to conjugated dienes

Hydrogen halides conjugated dienes

Hydrogen halides to conjugated dienes

Hydrogen-bonding additives in conjugated dienes

Hydrogenation of conjugated dienes

Hydromagnesiation conjugated dienes

Hydromagnesiation of Conjugated Dienes

Hydrometallation conjugated dienes

Hydrosilylation of conjugated dienes

INDEX conjugated dienes

Irradiation conjugated diene complexes

Isomerization conjugated dienes

Ketones conjugated diene synthesis

Key Concepts—Conjugation, Resonance, and Dienes

Kinetic control conjugated dienes

Kinetic control to conjugated dienes

Lactones conjugated dienes

Linoleic acid conjugated dienes value

Lipid hydroperoxides conjugated dienes value

Mechanism conjugated diene hydrogenation

Mechanism conjugated dienes

Metal conjugated dienes

Metallacycles conjugated dienes

Molecular mechanics conjugated diene polymerization

Molecular orbital conjugated diene

Nickel conjugated diene synthesis

Nuclear Overhauser enhancement spectroscopy of conjugated dienes

Nuclear magnetic resonance spectroscopy of conjugated diene complexes

Nuclear magnetic resonance spectroscopy of conjugated dienes

Nucleophilic reactions conjugated dienes

Nucleophilic substitution diene conjugation, allylic intermediates

Of conjugated dienes

Olefins double-bonded diene conjugation

Oxidation of conjugated dienes

Oxidative addition diene conjugation

Oxidative coupling conjugated dienes

Palladium catalysts conjugated dienes

Palladium complexes diene conjugation, allylic intermediates

Palladium conjugated diene synthesis

Palladium-catalysed reactions conjugated dienes

Palladium-catalyzed 1,4-additions conjugated dienes

Palladium-catalyzed 1,4-additions to conjugated dienes

Partition number, conjugated dienes

Photochemical cycloaddition conjugated dienes

Photochemistry of Conjugated Dienes and Trienes (Srinivasan)

Photopericyclic reactions of conjugated dienes

Polymerization Reactions of Conjugated Dienes

Polymerization of Conjugated Dienes Rubber

Preparation of Conjugated Dienes by 1,4-Elimination

Preparation of conjugated dienes

Radical addition of HBr to conjugated dienes

Reactions of Conjugated Dienes

Reduction of conjugated dienes

Regioselectivity conjugated diene reactions

Regioselectivity conjugated diene synthesis

Resonance conjugated dienes

Resonance energy conjugated dienes

Rhodium catalysts conjugated dienes

Rhodium-Catalyzed Hydrogenation of Alkynes and Conjugated Dienes

Ring structure diene-conjugated compounds

Rotational energy barrier conjugated dienes

Rubber, conjugated diene

Rubbers conjugated diene-based

Stability of Conjugated Dienes Molecular Orbital Theory

Stability of conjugated dienes

Stereochemistry conjugated diene hydrogenation

Stereochemistry conjugated dienes

Stereoisomerism of Conjugated Diene Polymers

Stereospecific polymerizations conjugated diene

Steric Control in Polymerizations of Conjugated Dienes

Studies with Conjugated Dienes

Substituted Acyclic Conjugated Dienes

Syndiotactic structures conjugated dienes

Synthesis of Conjugated (, )-Dienes

Synthesis of Conjugated (Z, )-Dienes

Synthesis of y-Lactams from Conjugated Diene-Magnesium Reagents

The Diels-Alder Reaction of Conjugated Dienes

The Stability of Conjugated Dienes

Transmetallation conjugated diene reactions

Two Neighboring Double Bonds Conjugated Dienes

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