Databases Chemical Abstracts Service

CAS. 1989. Chemical Abstracts Service (database). Chemical Abstracts. 

As of 05/2007, the Chemical Abstract Service database included ca. 140,000 entries containing the inositol keyword. 

Farmer, N.A. O Hara, M.P. CAS ONLINE A New Source of Substance Information from Chemical Abstracts Service . Database 1980, 3 (4), 10-25. 

There are a variety of databases that provide structural information to chemists. Two important examples are the Chemical Abstracts Services Database (CAS) and the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB). 

CAS = chemical abstracts service CDB = IFI/Plenem comprehensive code DWPI = Derwent world patents index INPI = Institut national de la propriete industrielle (the french patent office, producer of pharmsearch) MARPAT = chemical abstracts service database of Markush chemical structures from patents MDARC = Markush DARC MPHARM = pharmsearch Markush file, produced by INPI WPIM = world patents index Markush file. 

The term has different spellings Chemoinformatics and Cheminformatics. Searches in the database of the Chemical Abstracts Service have shown an approximately equal number of hits for both terms, with Cheminformatics gaining ground somewhat in recent years. Here, we use the spelling "Chemoinformatics" without trying to put forward reasons for that choice. 

The systematic lUPAC nomenclature of compounds tries to characterize compounds by a unique name. The names are quite often not as compact as the trivial names, which are short and simple to memorize. In fact, the lUPAC name can be quite long and cumbersome. This is one reason why trivial names are still heavily used today. The basic aim of the lUPAC nomenclature is to describe particular parts of the structure (fi agments) in a systematic manner, with special expressions from a vocabulary of terms. Therefore, the systematic nomenclature can be, and is, used in database systems such as the Chemical Abstracts Service (see Section 5.4) as index for chemical structures. However, this notation does not directly allow the extraction of additional information about the molecule, such as bond orders or molecular weight. 

More than 10 000 databases exist that provide a small or large amount of data on various topics (including chemistry). The contents in databases are supplied by approximately 3500 database developers (e.g., the Chemical Abstracts Service, MDL Information Systems, etc.). Since there is a variety of topics from economics to science, as well as a variety of structures of the database, only some of the vendors (-2000) offer one or more databases as either local or as online databases (Figure 5-4) [4]. Usually, databases are provided by hosts that permit direct access to more than one database. The search occurs primarily through different individual soft-... 

Typical bibliographic databases are the CA File of Chemical Abstracts Service CAS) or Medline of the US National Library of Medicine. Most electronic journals provide articles as full-text files, e.g., the Journal of the American Chemical Society ( ACS). 

It can be said that these three main strategies have been applied equally and very often in combination. Basically, the first approach implies the use of a faster computer or a parallel architecture. To some extent it sounds like a brute force approach but the exponential increase of the computer power observed since 1970 has made the hardware solution one of the most popular approaches. The Chemical Abstracts Service (CAS) [10] was among first to use the hardware solution by distributing the CAS database onto several machines. 

MARPAT, produced by Chemical Abstracts Service, coataias the geaeric stmcture records for pateat pubHcatioas siace 1988, which are iacluded ia the CA file. Sources iaclude pateats from 26 couatries plus EPO and PCT pubHcations. BibHographic records for retrieved references can be direcdy accessed ia this database (101). 

GORE. The CORE Electronic Chemistry Library is a joint project of Cornell University, OCLC (On-line Computer Library Center), Bell Communications Research (Bellcore), and the American Chemical Society. The CORE database will contain the full text of American Chemical Society Journals from 1980, associated information from Chemical Abstracts Service, and selected reference texts. It will provide machine-readable text that can be searched and displayed, graphical representations of equations and figures, and full-page document images. The project will examine the performance obtained by the use of a traditional printed index as compared with a hypertext system (SUPERBOOK) and a document retrieval system (Pixlook) (6,116). 

July 1993 STN Database Catalog, Chemical Abstracts Service, Columbus, Ohio, 1993, p. 4. 

Chemical Abstracts Service. The Chemical Abstracts Service (CAS), a division of the American Chemical Society, has produced Chemical Abstracts (CA) since 1907. Since the demise of Chemisches Zentralblatt and British Chemical Abstracts CA has been the preeminent medium for documenting new pubhcations in the field of chemistry and chemical engineering. CA documents chemical pubHcations of all types. It is not a patent database per se, but its patent component is larger than most databases devoted entirely to patents. Thus, for example, the number of patent references in CA for the years 1991—1993 ranged from 95,500—99,400 per year. 

Chemical Abstracts Service produces the world s largest and most comprehensive databases of chemical information. Principal databases, CHEMICAL ABSTRACTS (CA) and REGISTRY, include nearly 16 million abstracts of chemistry-related literature and patents and more than 30 million substance records respectively. 

Figure 1.2 Journals that have published the most papers on combinatorial library design. Total number of papers published on this subject according to the Chemical Abstract Service s CAPLUS and MEDLINE databases for all years through 2004 plus three-quarters of 2005.

The computer has added a new dimension to chemistry. Databases of chemical information are maintained not only for elements, but also for molecules. The database of substances at Chemical Abstracts Service reports more than 23 million registered substances. How can so many different substances and molecules be created from just over 100 different elements ... 

Finally, journal web sites and fee-based services can be used with success to find additional references to key topics. Examples of services that are particularly good include the American Chemical Society s Chemical Abstracts Service (CAS http //www.cas.org/) and their journal search page (http //pubs.acs.org/index.html) the Elsevier Scopus search engine (http //info. scopus.com/) and ScienceDirect database (http //www.sciencedirect.com/) and the ISI Web of Knowledge (http //isiwebofknowledge.com/). 

CAS Chemical Abstracts Service registry number. It is unique for each chemical without inherent meaning that and is assigned by the Chemical Abstracts Service, a division of the American Chemical Society. It allows for efficient searching of computerized databases. 

CASREACT Database of abstracts related to reaction chemistry, including hazard/safety information American Chemical Society (Chemical Abstract Service)... 

Chemicals are omnipresent in our world today. Chemical risk is a permanent issue in our everyday environment, obviously on work premises, and may also be caused by different circumstances of chemical assaults. Among all chemical accidents, eye projections are a specific issue because of the vulnerability of ocular structures and also because of the risk of major functional after-effects. Chemical Abstracts Service (CAS) is a division of the American Chemical Society. This International database of the American Chemical Society is a worldwide reference registering... 

Research articles of interest to biochemists may appear in many types of research journals. Research libraries do not have the funds necessary to subscribe to every journal, nor do scientists have the time to survey every current journal copy for articles of interest. Two publications that help scientists to keep up with published articles are Chemical Titles (published every 2 weeks by the American Chemical Society) and the weekly Current Contents available in hard copy and computer disks (published by the Institute of Science Information). The Life Science edition of Current Contents is the most useful for biochemists. The computer revolution has reached into the chemical and biochemical literature, and most college and university libraries now subscribe to computer bibliographic search services. One such service is STN International, the scientific and technical information network. This on-line system allows direct access to some of the world s largest scientific databases. The STN databases of most value to life scientists include BIOSIS Pre-views/RN (produced by Bio Sciences Information Service covers original research reports, reviews, and U.S. patents in biology and biomedicine), CA (produced by Chemical Abstracts service covers research reports in all areas of chemistry), MEDLINE, and MEDLARS (produced by the U.S. National Library of Medicine and Index Medicus, respectively cover all areas of biomedicine). These networks provide on-line service and their databases can be accessed from personal computers in the office, laboratory, or library. Some... 

Chemical Abstracts Service Registry database, Scifinder, (March 2006). 

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