CBl-cannabinoid receptor

Cannon CM, Palmiter RD (2003) Reward without dopamine, J Neurosci 23 10827-10831 Carboni E, Bortone L, Giua C, Di Chiara G (2000) Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug Alcohol Depend 58 93-102 Castane A, Valjent E, Ledent C, Parmentier M, Maldonado R, Valverde O (2002) Lack of CBl cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence. Neuropharmacology 43 857-867... [Pg.230]

The endocannabinoid system might also be involved, since A9-tetrahydorcan-nabinol, the major active ingredient in cannabis, decreases somatically expressed withdrawal behaviors and the aversiveness of withdrawal in mecamylamine- and naloxone-precipitated nicotine abstinence (Balfour 2002). However, genetic knockout of the CBl cannabinoid receptors did not significantly affect somatically expressed withdrawal behaviors (Castane et al. 2002). [Pg.423]

Leggett JD, Aspley S, Beckett SRG, D Antona AM, Kendall DA, Kendall DA, Oleamide is a selective endogenous agonist of rat and human CBl cannabinoid receptors, Brit JPharmacol 141 253—262, 2004. [Pg.75]

Mitchell, and M. Glass. Identification of the CBl cannabinoid receptor and CS337 fatty acid amide hydrolase (FAAH) in the human placenta. Placenta 2003 ... [Pg.109]

Gilgun-Sherki, Y., E. Melamed, R. Mechoulam, and D. Offen. The CBl cannabinoid receptor agonist, HU-210, reduces levodopa-induced rotations in 6-hydroxydopamine-lesioned rats. Pharmacol Toxicol 2003 93(2) 66—70. Pryce, G., Z. Ahmed, D. L. Hankey, et al. Cannabinoids inhibit neurodegeneration in models of multiple sclerosis. Brain 2003 126(Pt. 10) 2191-2202. Mathew, R. J., W. H. Wilson, and R. Davis. Postural syncope after marijuana a transcranial Doppler study of the hemodynamics. Pharmacol Biochem Behav 2003 75(2) 309-318. [Pg.109]

Kulkami-Narla A, Brown DR (2000) Localization of CBl-cannabinoid receptor immunoreactivity in the porcine enteric nervous system. Cell Tissue Res 302(l) 73-80 Kushmerick C, Price GD, Taschenberger H, Puente N, Renden R, Wadiche JI, Duvoisin RM, Grandes P, von Gersdorff H (2004) Retroinhibition of presynaptic Ca2+ currents by en-docannabinoids released via postsynaptic mGluR activation at a calyx synapse. J Neurosci 24(26) 5955-65... [Pg.472]

Rimonabant is an inverse agonist for CBl cannabinoid receptors, which is approved in Europe for weight-loss therapy, but has significant side effects on the central nervous system. [Pg.62]

Bisogno T (2008) Endogenous cannabinoids structure and metabohsm. J Neuroendociinol 20 1-9 Bisogno T, Melck D, Bobrov MY, Gretskaya NM, Bezuglov VV, De Petrocellis L, Di Marzo V (2000) N-acyl-dopamines novel synthetic CBl cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimemetic activity in vitro and in vivo. Biochem J 351 817-824... [Pg.488]

Ishii I, Chun J. Anandamide-induced neuroblastoma cell rounding via the CBl cannabinoid receptors. Neuroreport. 2002 13 593-596. [Pg.911]

Valverde O, Karsak M, Zimmer A. Analysis of the endocannabi-noid system by using CBl cannabinoid receptor knockout mice. Handb. Exp. Pharmacol. 2005 117-145. [Pg.911]

Antel, J., Gregory, P. C., Nordheim, U. CBl cannabinoid receptor antagonists for treatment of obesity and prevention of comorbid metabolic disorders. J. Med. Chem. 2006,49(14), 4008-4016. [Pg.361]

Jarrahian A, Watts VJ, Barker EL (2004) D2 dopamine receptors modulate Ga-subunit coupling of the CBl cannabinoid receptor. J Pharmacol Exp Ther 308 880-886... [Pg.45]

Pertwee RG (1999b) Evidence for the presence of CBI cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CBl cannabinoid receptors. Life Sci 65 597-605... [Pg.47]

Rinaldi-Carmona M, Calandra B, Shire D, Bouaboula M, Oustric D, Barth F, Casellas P, Ferrara P, Le Fur G (1996a) Characterization of two cloned human CBl cannabinoid receptor isoforms. J Pharmacol Exp Ther 278 871-878... [Pg.48]

Rinaldi-Carmona M, Pialot F, Congy C, Redon E, Barth F, Bachy A, Breli re J-C, Soubri P, Le Fur G (1996b) Characterization and distribution of binding sites for [3H]-SR141716A, a selective brain (CBl) cannabinoid receptor antagonist, in rodent brain. Life Sci 58 1239-1247... [Pg.48]

Wager-MUler J, Westenbroek R, Mackie K (2002) Dimerization of G protein-coupled receptors CBl cannabinoid receptors as an example. Chem Phys Lipids 121 83-89... [Pg.50]

Howlett AC, Song C, Berglund BA, Wilken GH, Pigg JJ (1998) Characterization of CBl cannabinoid receptors using receptor peptide fragments and site-directed antibodies. Mol Pharmacol 53 504-510... [Pg.73]

Zhou D, Song ZH (2001) CBl cannabinoid receptor-mediated neurite remodeling in mouse neuroblastoma NIE-115 cells. J Neurosci Res 65 346-353... [Pg.79]

Zhou D, Song ZH (2002) CBl cannabinoid receptor-mediated tyrosine phosphorylation of focal adhesion kinase-related non-kinase. FEBS Lett 525 164-168... [Pg.79]

Garcia DE, Brown S, HiUe B, Mackie K (1998) Protein kinase C disrupts cannabinoid actions by phosphorylation of the CBl cannabinoid receptor. J Neurosci 18 2834-2841... [Pg.108]

CBl Cannabinoid Receptors Participate in the Control of Cognitive Functions 122... [Pg.117]

Castane A, Valjent E, Ledent C, Parmentier M, Maldonado R, Valverde O (2002) Lack of CBl cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence. Neuropharmacology 43 857-867... [Pg.138]

Katona I, Sperlagh B, Sik A, Kafalvi A, Vizi ES, Mackie K, Freund TF (1999) Presynaptically located CBl cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. J Neurosci 19 4544-4558... [Pg.141]

Guo J, Ikeda SR (2004) Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CBl cannabinoid receptors heterol-ogously expressed in mammalian neurons. Mol Pharmacol 65 665-674... [Pg.178]

Marsicano G, Goodenough S, Monory K, Hermann H, Eder M, Cannich A, Azad SC, Cascio MG, Gutierrez SO, van der Stelt M, Lopez-Rodriguez ML, Casanova E, Schutz G, Zieglgansberger W, Di Marzo V, Behl C, Lutz B (2003) CBl cannabinoid receptors and on-demand defense against excitotoxicity. Science 302 84-88... [Pg.181]

Ravinet Trillou C, Delgorge C, Menet C, Arnone M, Soubrie P (2004) CBl cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28 640-648... [Pg.183]

Sagan S, Venance L, Torrens Y, Cordier J, Glowinski J, Giaume C (1999) Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CBl cannabinoid receptors in cultured astrocytes. Eur J Neurosci 11 691-699... [Pg.183]

Picone RP, Fournier DJ, Makriyannis A (2002) Ligand based structural studies of the CBl cannabinoid receptor. J Pept Res 60 348-356... [Pg.244]

Abood ME, Ditto KE, Noel MA, Showalter VM, Tao Q (1997) Isolation and expression of a mouse CBl cannabinoid receptor gene. Comparison of binding properties with those of native CBl receptors in mouse brain and N18TG2 neuroblastoma cells. Biochem Pharmacol 53 207-214... [Pg.273]

PanX, Ikeda SR, Lewis DL (1998) SR 141716A acts as an inverse agonist to increase neuronal voltage-dependent Ca2-I- currents by reversal of tonic CBl cannabinoid receptor activity. Mol Pharmacol 54 1064-1072... [Pg.278]

Soderstrom K, Johnson F (2000) CBl cannabinoid receptor expression in brain regions associated with zebra finch song control. Brain Res 857 151-157... [Pg.297]

Soderstrom K, Johnson F (2001) Zebra finch CBl cannabinoid receptor pharmacology and in vivo and in vitro effects of activation. J Pharmacol Exp Ther 297 189-197... [Pg.297]

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