Toxic Substances Control Program

Hazardous Waste Reduction Checklist and Assessment Manualfor the Metal FinishingJndusty, California Department of Health Services, Alternative Technology Division, Toxic Substances Control Program, Sacramento, Calif., 1990. 

Toxic Substances Control Program Regional Offices... 

Region 1 — Sacramento Toxic Substances Control Program 10151 Croydon Way Sacramento, CA 95827 (916) 855-7700... 

Toxic Substances Control Program 5545 East Shields Avenue Fresno. CA 93727 (209)445-5938... 

Region 2 — Berkeley Toxic Substances Control Program 700 Heinz Ave, Bldg. F Berkeley, CA 94710 (415)540-2122... 

Region 3 — Burbank Toxic Substances Control Program 1405 Nonh San Fernando Blvd. Burbank, CA 91504 (818) 567-3000... 

Region 4 — Long Beach Toxic Substances Control Program 245 West Broadway. Suite 350 Long Beach. CA 90802 (213) 590-4868... 

Alternative Technology Division Toxic Substances Control Program California Department of Health Services P.O. Box 942732 Sacramento, CA 94234-7320 (916) 324-1807... 

Dichloropropane (1,2-D), 1,3-Dichloropropene (1,3-D)" Toxic Substances Control Program, California State Water Resources Control Board, Special Projects Report No. 83-8sp, 1983. 

Cohen, D.B., and Bowers, G.W. Water Quality and Pesticides A California Risk Assessment Program (Yol. 1), State Water Resources Control Board, Toxic Substances Control Program, Sacramento, CA, November, 1984. 

In order to answer the question are there any more DBCP-type problems out there awaiting discovery, the State Board in May 1980 established a Toxic Substances Control Program. A major focus of this program was development of an "early warning" priority chemicals project to (1) assess risks, (2) recommend water quality objectives, and (3) propose appropriate mitigation measures for agricultural and industrial chemicals most likely to adversely impact surface or ground water quality. 

Operating under contract to EPA, the TCSA Hotline provides technical assistance and information about programs under the Toxic Substances Control Act (TSCA), including the Asbestos School Hazard Abatement Act (ASHAA), the Asbestos Hazard Emergency Response Act (AHERA), and the Lead Exposure Reduction Act. Hours 8 30 a.m. - 5 00 p.m. EST weekdays. 

Fourteen formulations of chemical alternatives were submitted to EPA under confidentiality and they were assessed based on numerous human health and ecotoxicity endpoints in addition to bioaccumulation potential and environmental persistence. They were also screened for potential exposure to workers, users and the aquatic environment. Where data gaps existed, EPA experts used models and chemical analogs to estimate the hazard for a particular endpoint. The literature and test data reviews were published in the final report, Environmentally Preferable Options for Furniture Fire Safety Low Density Furniture Foam . In addition, each hazard endpoint was ranked with a concern level (High, Moderate or Low) based on the criteria used by the EPA s New Chemicals Program to rate the concern level of new chemicals submitted under the Toxic Substance Control Act (TSCA). As seen in Figure 8.2, where the hazard endpoint rankings are bold, the value is based on experimental data. Where the hazard endpoints are presented in italic font, the value is estimated based on models or chemical analogs. In this way, detailed hazard information was summarized and presented in a clear and concise format. 

The Toxic Substances Control Act (TSCA) refers to "new chemicals" as those not on the TSCA Inventory of Chemical Substances which lists about 55,000 existing commercial chemicals. All new chemicals must enter EPA s premanufacture notification program (PMN) for review before manufacture. This program is the most complete record of development of new chemicals by U.S. industry over the past 2 1/2 years. To date over 1,000 notices have been submitted, many including confidential business information (CBI). Despite the CBI, it is possible to summarize EPA s experience with new chemical substances and to evaluate the PMN program and its impact on product innovation. That is essentially the aim of this paper. 

NPDES = National Pollutant Discharge Elimination System NTP = National Toxicology Program OSHA = Occupational Safety and Health Administration OW = Office of Water PCB = Polychlorinated Biphenyl RfD = Reference Dose STEL = Short-term Exposure Limit TLV = Threshold Limit Value TSCA = Toxic Substances Control Act TWA = Time Weighted Average WHO = World Health Organization... 

Under the Toxics Substances Control Act, the Environmental Protection Agency (EPA) is mandated to gather data on the exposure of the general population to toxic substances. Toward this end, the Office of Toxic Substances within the EPA has undertaken several long term monitoring programs. These programs involve the collection of human tissue specimens from a statistically representative... 

If one s purpose is to determine only the presence or absence in a data base of a specific structure, this can be accomplished with the search option IDENT , as is shown in Figure 11. This program hash-encodes the query structure connection table and searches through a file of hash-encoded connection table for an exact match. The search, which is very fast by substructure search standards, has been designed specifically for those users who, to comply with the Toxic Substances Control Act [26l have to determine the presence or absence of specific compounds in Environmental Protection Agency files. 

US-EPA. 2006c. The United States Environmental Protection Agency Toxic Substances Control Act New Chemicals Program website, www.epa.gov/opptintr/newchems US-EPA. 2006d. United States Environmental Protection Agency Test guidelines, http //www.epa. 

Within a year of the act s adoption, the EPA had assigned responsibility for its implementation to the Office of Pollution Prevention and Toxics, formed in 1977 to administer the Toxic Substances Control Act, and had begun the first federally funded green chemistry programs. By 1992, the National Science Foundation had also begun funding research on "environmentally benign [chemical] syntheses and processes."... 

Environmental Protection Agency. Toxic substances control Good laboratory practice standards Final rule. Fed Reg 48 53921-53944, 1983 Environmental Protection Agency. Pesticides program Good laboratory practice standards Final rule. Fed Reg 48 53945-53969, 1983. 

CMA. 1984. Voluntary Testing Program under Section 4 of the Toxic Substances Control Act. Submission of Test Data. Volume III. Isophorone Mutagenicity Studies. Unpublished studies performed by Microbiological Associates, Bethesda, MD for Chemical Manufacturers Association, Washington, DC. OTS Section 4 submission. Doc. ID. 40-8455047. Microfiche No. OTS0507222. 

California s Waste Reduction Program is located in the Alternative Technology Section, Toxic Substances Control Division, Department of Health Services. 

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