Study performance

Alkylamines and diamines are generally classified as corrosive to the skin based on results from laboratory animal (rabbit) studies performed in accordance with the Department of Transportation (DOT) test method (84) rabbits are considered to be especially sensitive to alkylamines which even at low concentrations can induce skin redness and swelling. Oleylamine has been shown to induce mild to moderate skin irritation in laboratory rats when appHed at a concentration of 0.3% in mineral oil (Chemical Manufacturer s Association, 1985). Fatty amines which contain alkyl chains of 10—14 carbons are considered more irritating than related products which contain alkyl chains of 14—18 carbon atoms. Ethoxylation generally decreases the irritation potential of alkylamines. 

Table 4. Nuclear Medicine Studies Performed in the United States, 1988-1993 ...

Mn Inhalation Teratology Study in Rats with Cyclohexanone, a study performed by Bio/dynamics, Inc., East Millstone, N.J., for The Industrial Health Foundation, Aug. 1984. 

A detailed study performed by McKay et al. (1989) revealed some of the conditions necessary for a turbulent jet to initiate a detonation directly. These experiments are covered in more detail in Section 4.1.5. 

Risk study (CPQRA or PRA) Specific study performed on a particular facility to determine the areas of weakness and strength in equipment and plant performance reliability may include consequence analysis and usually implies some judgment of the risk. 

The study performed by Burns and Roe (BSR) shows that valve failures constitute the component category most responsible for the shutdown of PWR and BWR plants. This Investigation, contracted with SNL for DOE, identified the principal types and causes of valve failures that led to plant trips for the period from 12/72 to 12/78. The primary sources of data for the report were searches of the data base, the monthly Gray Books, Nuclear Power Experience publications, as well as discussions with utilities, valve manufacturers, and suppliers. 

For a more extended study, perform an optimization on each of these molecules ... 

A similar study performed by Welton and co-workers studied the rate and selec-tivities of the Diels-Alder reaction between cyclopentadiene and methyl acrylate in a number of neutral ionic liquids [44]. It was found that endo. exo ratios decreased slightly as the reaction proceeded, and were dependent on reagent concentration and ionic liquid type. Subsequently, they went on to demonstrate that the ionic liquids controlled the endo. exo ratios through a hydrogen bond (Lewis acid) interaction with the electron-withdrawing group of the dienophile. 

To understand how the dispersed phase is deformed and how morphology is developed in a two-phase system, it is necessary to refer to studies performed specifically on the behavior of a dispersed phase in a liquid medium (the size of the dispersed phase, deformation rate, the viscosities of the matrix and dispersed phase, and their ratio). Many studies have been performed on both Newtonian and non-Newtonian droplet/medium systems [17-20]. These studies have shown that deformation and breakup of the droplet are functions of the viscosity ratio between the dispersity phase and the liquid medium, and the capillary number, which is defined as the ratio of the viscous stress in the fluid, tending to deform the droplet, to the interfacial stress between the phases, tending to prevent deformation ... 

Production Test. In a small-scale production test, tinplate containers with two commercially available enamels and two end-sealing compounds, which were selected from the results of this study, performed satisfactorily when packed with beef and ham. Beef was irradiated with 4.5-5.6 Mrad at 5, —30, and —90°C ham was irradiated with 3-4 Mrad and 6-7.5 Mrad at —30°C. For this production test, beef and ham were packaged in round tinplate containers and ham in Pullman tinplate containers, frozen and refrigerated products were shipped 1,200 miles by truck, and were gamma irradiated at various doses and temperatures. Irradiated products were shipped 1,200 miles in a non-refrigerated truck and stored at selected temperatures and humidities. The integrity of the cans was evaluated after storage for 10 days, 3 months, and 6 months. 

An example of this process is the study performed by Lewis and Storch20 in 1917 to determine the activity of Br2(2) in aqueous solutions. First, they... 

From the detailed studies performed either using individual alcohol sulfates and alcohol ether sulfates or formulated products by oral administration and skin contact, no evidence of carcinogen risk was found. Similar conclusions were obtained when these sulfates or formulated products were tested for mutagenic and teratogenic properties. 

Study performed at the National Institue of Petroleum and Energy Research. bRelative to active surfactant concentration. 

Not much effort has been made, except for the Tafel studies, to establish the empirical kinetics and models of interfacial reactions to obtain thick polymeric films (>100 nm) of industrial interest from different monomers. However, this is much more than the few kinetic studies performed until now to understand the mechanism of chemically initiated polymerization. Electrochemical models still have an advantage in obtaining priority in the industrial production of tailored materials. 

Sec. 58.10 Applicability to studies performed under grants and contracts. 

A mechanistic study performed by the authors showed that CALB and EtOAc are required for racemization to take place. They claimed that enzyme-catalyzed oxidation of the amine substrate takes place, and a ketone intermediate is produced. The ketone reacts with the substrate to form an enamine. This process results in racemization of the substrate (Figure 4.34). It is not clear how the enzyme and EtOAc could dehydrogenate the amine. 

Very little evidence associating water scarcity and an increase in outbreaks of faecal-oral water-borne infectious diseases exists in developed countries. A recent retrospective study performed in England provides some evidence that both low rainfall and heavy rain precede many drinking water outbreaks [3]. Yet, as stated earlier in this review, the situation is potentially different in developing countries [5-7, 9-12], where water scarcity, including droughts, leads to different circumstances that have a clear incidence in the occurrence of both water-borne and water-washed infectious diseases. 

Olivares et al. (2006), studies performed viscometers very dilute gelatin solutions with concentrations between 10-5 and 10-3 g/cm3, where either intermolecular aggregation or intramolecular folding are possible, respectively, and the sol-gel transition is not observed. 

Investigation of the polypeptide folding properties of iron-sulfur via NMR spectroscopy began in 1997 (122). All studies performed to date have focused on the effect of the addition of guanidinium chloride (GdmCl hereafter) to protein solutions. Under these conditions, re-... 

Fe-4S] D. gigas Fdll structure is the only high-resolution crys-tallograph study performed in ferredoxins isolated from SRB (56)... 

Electrochemical studies performed in the 7 x Cys-Aspl4 D. afri-canus Fdlll indicate that the reduced [3Fe-4S] center can react rapidly with Fe to form a [4Fe-4S] core that must include noncysteinyl coordination (101). The carboxylate side chain of Asp 14 was proposed as the most likely candidate, since this amino acid occupies the cysteine position in the typical sequence of a 8Fe protein as indicated before. The novel [4Fe-4S] cluster with mixed S and O coordination has a midpoint redox potential of 400 mV (88). This novel coordinated state with an oxygen coordination to the iron-sulfur core is a plausible model for a [4Fe-4S] core showing unusual spin states present in complex proteins (113, 114). 

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