GC in pharmaceutical analysis

GC is used widely for analysis in the pharmaceutical industry, and applications for assays and impurity profiles for raw materials, intermediates and APIs are commonplace. GC is often chosen as the method of analysis when compounds have poor or widely different UV chromophores. A common case is when the 

GC is the most commonly used technique for residual solvent and organic volatiles analysis in API and has also found application where trace level detection of analytes is required. An airborne monitoring method for SB-202026-A (8) was required and due to the low occupational exposure limit (OEL) for this molecule it was necessary to be able to quantify (8) in solutions at 100ngml . This was achieved readily using a 1 microhtre splitless injection. 

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