Sensitive data

More recent research provides reversible oxidation-reduction potential data (17). These allow the derivation of better stmcture-activity relationships in both photographic sensitization and other systems where electron-transfer sensitizers are important (see Dyes, sensitizing). Data for an extensive series of cyanine dyes are pubflshed, as obtained by second harmonic a-c voltammetry (17). A recent "quantitative stmcture-activity relationship" (QSAR) (34) shows that Brooker deviations for the heterocycHc nuclei (discussed above) can provide estimates of the oxidation potentials within 0.05 V. An oxidation potential plus a dye s absorption energy provide reduction potential estimates. Different regression equations were used for dyes with one-, three-, five-methine carbons in the chromophore. Also noted in Ref. 34 are previous correlations relating Brooker deviations for many heterocycHc nuclei to the piC (for protonation/decolorization) for carbocyanine dyes the piC is thus inversely related to oxidation potential values. 

Insol in w, si sol in acet ac, sol in dil nitric ac fixed alkali hydroxides. Poisonoust Warren (Ref 1) evaluated Pb oxalate as a possible replacement for MF in primer compns, and concluded that it lacked the sensitivity necessary for an initiating agent. Sensitivity data obtained are given below ... 

Their impact and friction sensitivity data appear to be monotonic functions of corrected OB, but the relation between corrected OB and Trauzl Block data appears to be complex... 

The raw data of fires and no-fires is translated into meaningful sensitivity data by use of a calcn sheet shown in Table 1... 

The importance of frictional heating in the initiation of expls is a subject of considerable importance. The frictional sensitivity is directly involved in the handling hazards of all high-energy materials and considerable attention has been directed toward gathering of frictional sensitivity data on almost all mil expls, in addi- tion to an entire host of pyrotechnic mixts and certain propints (Refs 6 17)... 

Phase-sensitive data acquisition NMR data are acquired in this manner so that peaks are recorded with pure absorption-mode or pure dispersionmode line shapes. 

Antibiotic selection is based on periodic culture and sensitivity data, typically covering all organisms identified over the preceding year. If no culture data are available, empiric antibiotics should cover the most likely organisms for the patient s age group. 

Is the patient currently on antibiotics, and if so, are the symptoms improving Recommend an appropriate antibiotic regimen based on culture and sensitivity data. 

Components of a monitoring plan to assess the efficacy and safety of antimicrobial therapy of CNS infections include clinical signs and symptoms and laboratory data (such as CSF findings, culture, and sensitivity data). 

Empirical therapy for postoperative infections in neurosurgical patients (including patients with CSF shunts) should include vancomycin in combination with either cefepime, ceftazidime, or meropenem. Linezolid has been reported to reach adequate CSF concentrations and resolve cases of meningitis refractory to vancomycin.35 However, data with linezolid are limited. The addition of rifampin should be considered for treatment of shunt infections. When culture and sensitivity data are available, pathogen-directed antibiotic therapy should be administered. Removal of infected devices is desirable aggressive antibiotic therapy (including high-dose intravenous antibiotic therapy plus intraventricular vancomycin and/or tobramycin) may be effective for patients in whom hardware removal is not possible.36... 

How are laboratory data (including culture sensitivity data) used to refine empirical antibiotic regimen ... 

Monitor culture and sensitivity data from the microbiology laboratory to determine whether any refinements are needed in the patient s treatment regimen. Design a therapeutic plan to finish out the patient s course of therapy for acute meningitis. 

Narrow antibiotic coverage when possible with the use of culture and sensitivity data. 

Empiric antimicrobial therapy should target likely causative pathogen(s) based on patient-specific risk factors and route of infection. However, therapy should be modified based on culture and sensitivity data. 

The 193 nm light from a Questek ArF excimer laser was used to obtain sensitivity data by exposing 1 cm2 areas. Fine line patterning with 193 nm light was done on a Leitz IMS exposure apparatus with either 15X or 36X reflective objectives. The fluence was varied from 0.1 to 100 mJ/cm2/pulse. All exposures at 248 nm were conducted on a deep-UV stepper(12) with a NA = 0.38 lens, 5X reduction, a minimum feature size of 0.4 pm and a fluence of -0.3 mJ/cm2/pulse. 

Sensitivity data for 193 nm exposures were obtained by imaging 1 mm to 1 cm diameter spots in a 1.2 pm thick poly(styrene) film using a Questek ArF excimer laser. Sensitivity was found to be a function of the fluence. For example, one pulse was sufficient to result in a full thickness image after treatment with TiCU and O2 RIE when the fluence was 6 mJ/cm2/pulse (Figure 10). Considerably more dose (32 mJ/cm2) was required to obtain the same result when the fluence was 1... 

Figure 4. Spectral sensitivity data of PMMA and sensitized PMMA obtained by the equipment shown in Figure 3 (A) PMMA (B) PMMA -f- p-teit-butyl benzoic acid (C) PMMA + 2,4-di-tert-butylphenol (D) PMMA + 2,4,6-tri-teit-butyl-...

It is worth noting that attacks may come from either outside or within the system (i.e., from an insider), and that network intrusion detection systems may be more applicable for detecting patterns of suspicious activity from inside a facility (i.e., accessing sensitive data, etc.) than are other information technology solutions. 

According to the above definition, sensitivity does not only depend on the ionization efficiency of El or any other ionization method. Also relevant are the extraction of ions from the ion source, the mass range acquired during the experiment, and the transmission of the mass analyzer. Therefore, the complete experimental conditions have to be stated with sensitivity data. 

Ionization in Cl is the result of one or several competing chemical reactions. Therefore, the sensitivity in Cl strongly depends on the conditions of the experiment. In addition to primary electron energy and electron current, the reagent gas, the reagent gas pressure, and the ion source temperature have to be stated with the sensitivity data to make a comparison. Modem magnetic sector instmments are specified to have a sensitivity of about 4 x 10" C pg for the [Mh-H] quasi-molecular ion of methylstearate, m/z 299, at / = 1000 in positive-ion Cl mode. This is approximately one order of magnitude less than for El. 

The fragility of the five data types will depend on the specific circumstances of the incident. It is not possible to offer a prescribed priority. In general, historical paper data such as procedures, maintenance records, and drawings are less fragile than people and physical data. The team should identify time-sensitive data as one of its first tasks, prioritize the data, and implement measures to collect or preserve the data. 

Some examples of time-sensitive data are outlined below. 

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