Regimen for treatment

When designing a drug regimen for treatment of IBD, several factors should be considered, including the patient s symptoms, medical history, current medication use, drug allergies, and location and severity of disease. 

TABLE 72-2. Recommended Drug Regimens for Treatment of Latent Tuberculosis Infection (LTBI) in Adults32... 

Recommend an appropriate antimicrobial regimen for treatment of a primary and a secondary intrabdominal infection. 

The recommended regimen for treatment is metronidazole, 500 mg twice daily for 7 days metronidazole, 250 mg three times daily for 7 days or clindamycin, 300 mg twice daily for 7 days. 

Recommended regimens for treatment of chlamydial infections are given in Table 46-8. Single-dose azithromycin and 7-day doxycycline are the... 

Acne The timing of dosing with Ortho Tri-Cyclen or Estrostep for acne should follow the guidelines for use of Ortho Tri-Cyclen or Estrostep as an OC. The dosage regimen for treatment of facial acne uses a 21-day active and a 7-day inert schedule. Take 1 active tablet daily for 21 days followed by 1 inert for 7 days. After 28 tablets have been taken, a new course is started the next day. 

Unlabeled Uses Part of multidrug regimen for treatment of MAC... 

On October 21, 2008, FDA granted traditional approval to Prezista (darunavir), co-administered with ritonavir and with other antiretroviral agents, for the treatment of HIV-1 infection in treatment-experienced adult patients. In addition to the traditional approval, a new dosing regimen for treatment-naive patients was approved. 

Recommended Drug Regimens for Treatment I of Latent Tuberculosis (TB) Infection in Adults... 

Pediatric Eye Disease Investigator Gronp. A randomized trial of atropine regimens for treatment of moderate amblyopia in children. Ophthalmology 2004 111 2076-2085. 

Smithuis FM, van Woensel JB, Nordlander E, Vantha WS, ter Kuile FO. Comparison of two mefloquine regimens for treatment of Plasmodium falciparum malaria on the northeastern Thai-Cambodian border. Antimicrob Agents Chemother 1993 37(9) 1977-81. 

TABLE 76—1. Recommended Regimens for Treatment of Cervical Infections Due to Chlamydia in Pregnancy... 

The 5-year survival in children with AML has increased from 17% in 1976 to 50% in 2000. Children with Down s syndrome and AML receive less intense therapy and have EFS of 68% to 100%. Treatment of AML, unlike that of ALL, usually only consists of induction and intensive post-remission therapy (see Fig. 131-1). CNS prophylaxis is not routinely given in adult AML (with the exception of some M4 and M5 leukemias), but is generally administered to pediatric patients. Table 131-11 presents several representative induction regimens for treatment of adult AML. ... 

Answer C. All of the drugs listed are antimetabolites used in cancer chemotherapy or as immunosuppressants. The 5-fluorouracil is bioactivated to 5-fluorodeoxyuridine monophosphate (5-FdUMP), a substrate for and inhibitor of thymidylate synthase. When used in drug regimens for treatment of cancer, 5-FU causes thymineless death of cells. 

Cohn, D. L., Fisher, E., Franchino, B., et al. (1996). Comparison of two doses of clarithromycin in a randomized trial of four 3-drug regimens for treatment of disseminated Mycobacterium avium complex disease in AIDS Excess mortality associated with high dose clarithromycin. Presented at 11th International Conference on AIDS (Vancouver, B.C., Canada). 

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