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Screening for hepatitis

Singer ME, Younossi ZM (2001) Cost effectiveness of screening for hepatitis C virus in asymptomatic, average-risk adults. Am J Med 111 614—621... [Pg.69]

Histaglobulin is thoroughly screened for hepatitis B surface antigen and anti HIV using third generation technique RIA and ELISA and is found to be non-reactive. [Pg.447]

Farrell M, Battersby M Strang J (1990). Screening for hepatitis B and vaccination of injecting drug users in NHS drug treatment services. British Journal of Addiction, 85, 1657-9... [Pg.155]

The mirtazapine studies did not screen for hepatitis C as an exclusionary criterion for study enrollment, so these elevations may have been due to the periodic exacerbations of this chronic infection rather than being caused by the drug. [Pg.152]

Serum alkaline phosphatase elevation is of some value in screening for hepatic metastases (F4, G18, S9, W19). However, in one series (G18), 23% of patients with proven metastases had normal serum alkaline phosphatase values, while elevated values were seen in 6 of 23 patients who were subsequently shown to be free of hepatic metastases (G18). White et al. (W19), who studied 146 patients with metastatic breast cancer, found that only 2 of 39 patients with positive liver scans had normal serum alkaline phosphatase values (see also Section 10.1). [Pg.208]

Most health care workers are at risk for exposure to many diseases in the normal course of their work. Additionally, health care workers may transmit vaccine-preventable diseases to their patients. At the time of employment and on a regular basis, health care workers should be screened for immunity to measles, rubella, and varicella if found to be non-immune, the measles, mumps, and rubella, and varicella vaccines should be administered. The hepatitis B series should be given if not already completed. Tetanus should be updated and given every 10 years. Health care personnel in hospitals and ambulatory settings with direct patient contact should receive Tdap if not already received an interval as short as 2 years from the last tetanus-containing vaccine should be used. Priority for receiving Tdap should be given to personnel with direct contact with infants less than 12 months of age. [Pg.1250]

Biopharmaceutical products are also subjected to screening for the presence of viral particles prior to final product release. Although viruses could be introduced, for example, via infected personnel during downstream processing, proper implementation of GMP minimizes such risk. Any viral particles found in the finished product are most likely derived from raw material sources. Examples could include HIV or hepatitis viruses present in blood used in the manufacture of blood products. Such raw materials must be screened before processing for the presence of likely viral contaminants. [Pg.197]

Native factor VIII is traditionally purified from blood donations first screened for evidence of the presence of viruses such as hepatitis B and HIV. A variety of fractionation procedures (initially mainly precipitation procedures) have been used to produce a factor VIII product. The final product is filter-sterilized and filled into its finished product containers. The product is then freeze-dried and the containers are subsequently sealed under vacuum, or are flushed with an inert gas (e.g. N2) before sealing. No preservative is added. The freeze-dried product is then stored below 8 °C until shortly before its use. [Pg.336]

In order to identify novel lead compounds with antiviral effects, methanol and aqueous extracts of some medicinal plants in the Zingiberaceae family were screened for inhibition of proteases from human immunodeficiency virus type 1 (HIV-1), hepatitis C virus (HCV) and human cytomegalovirus (HCMV). By bioassay-guided fractionation, eight fiavones were isolated from the black rhizomes of Kaempferia parviflora Wall, ex Baker. The most effective inhibitors, 5-hydroxy-7-methoxyfiavone and 5,7-dimethoxyflavone, inhibited HIV-1 protease, with an inhibitory concentration 50 (IC50) values of 19 0,M. Moreover, 5-hydroxy-3,7-dimethoxyflavone inhibited HCV protease and HCMV protease, with IC50 values of 190 and 250 pM, respectively. [Pg.452]

Patients receiving opioid analgesics opioid-dependent patients patients in acute opioid withdrawal failed naloxone challenge positive urine screen for opioids history of sensitivity to naltrexone acute hepatitis or liver failure. [Pg.388]

Contraindications Acute hepatitis, acute opioid withdrawal, failed naloxone challenge test, hepatic failure, history of hypersensitivity to naltrexone, opioid dependence, positive urine screen for opioids... [Pg.843]

In these experiments, as in most of the others at Edgewood, routine biochemical tests were used to screen for unexpected hepatic or renal toxicity. No clinically significant abnormalities were noted in the records. [Pg.72]

In patients with chronic hepatic B or C the respective prevalences of pancreatic autoantibodies increased from 2% and 3% at baseline to 5% and 7% after interferon (544). In all, 31 published cases of type 1 diabetes mellitus attributed to interferon alfa treatment were detailed, mostly in patients with hepatitis C. Irreversible diabetes required permanent insulin treatment in all but eight cases. At least one marker of pancreatic autoimmunity was positive in nine of 18 patients before treatment, and in 23 of 30 patients at the onset of diabetes. In accordance with these results and the likelihood of a genetic predisposition, the authors recommended screening for islet cell and glutamic acid decarboxylase autoantibodies before and during interferon alfa treatment. However, owing to the low number of reported cases and the paucity of studies that have examined the relation between pancreatic autoimmunity and the occurrence of diabetes, further research on the predictive potential of such a systematic investigation is warranted. [Pg.610]

The first organic derivative of DTPA to be screened for medicinal application was the pentaethyl ester which was examined for ability to reduce hepatic deposits of plutonium in mice120. Although superior to DTPA in removing plutonium from mice, this derivative was too toxic for further use. [Pg.105]

The gestational age of the infant is a major factor in the development of neonatal hyperbilirubinemia. The more premature the infant is, the lower the level of expression of the enzymes necessary for synthesis of conjugated bilirubin (discussed in the section on Hepatic Metabolism of Bilirubin) and the more likely the child is to develop jaundice. Babies are not routinely screened for the cause of jaundice until the condition manifests itself. Testing would be instituted early if there were a sibling who had experienced prolonged jaundice, or if the mother is blood type O or is Rh negative. All mothers who have good prenatal care are tested for blood type and Rh antibodies. This alerts the physician to potential problems and allows the physician to anticipate the most common forms of jaundice, namely, ABO incompatibilities. [Pg.235]

Healthy male subjects, aged 18-45 years (inclusive), with a Body Mass Index between 18 and 27 kg/m2 (inclusive), normal or clinically irrelevant abnormal findings (in the opinion of the investigator) in the medical history and physical examination, laboratory values, ECG, blood pressure and pulse rate, negative serology (HIV antibody, hepatitis B surface antigen, hepatitis C antibody) and urine screen for drugs of abuse. [Pg.674]

Larcos, G., Sorokopud, H., Berry, G., Farell, G.C. Sonographic screening for hepatocellular carcinoma in patients with chronic hepatitis or cirrhosis an evaluation. Amer. X. Roentg. 1998 171 433-435... [Pg.746]

Hepatitis B vims (HBV) Since the detection of HBsAg by Blnmberg and the introdnction of HBsAg screening for donors of blood and plasma in aU developed countries, hepatitis B virns transmission throngh the use of blood and blood prodncts has been effectively prevented. Estimates of the risk of infection, based on the sensitivities of cnrrent tests for HBsAg and for anti-HBcAg, are in the order of 1 in 200000 per nnit (159). [Pg.537]

A 54-year-old man received interferon alfa-2a, 9 MU/ day, for chronic hepatitis C. He developed an asymptomatic right pleural effusion after 14 days. Although his serum titer of antinuclear antibodies was slightly increased, a more complete screening for autoimmune disease was negative. An infectious origin was also ruled out. The pleural effusion spontaneously disappeared after interferon alfa withdrawal and did not recur. [Pg.1796]


See other pages where Screening for hepatitis is mentioned: [Pg.427]    [Pg.2163]    [Pg.658]    [Pg.113]    [Pg.427]    [Pg.2163]    [Pg.658]    [Pg.113]    [Pg.536]    [Pg.42]    [Pg.1013]    [Pg.154]    [Pg.292]    [Pg.141]    [Pg.239]    [Pg.785]    [Pg.307]    [Pg.414]    [Pg.174]    [Pg.119]    [Pg.337]    [Pg.369]    [Pg.618]    [Pg.811]    [Pg.313]    [Pg.764]    [Pg.604]    [Pg.279]    [Pg.254]    [Pg.605]    [Pg.409]    [Pg.454]    [Pg.585]   
See also in sourсe #XX -- [ Pg.278 , Pg.279 ]

See also in sourсe #XX -- [ Pg.278 , Pg.279 ]




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Screening for

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