Surface antigen

Vaccines can be roughly categorized into killed vaccines and Hve vaccines. A killed vaccine can be (/) an inactivated, whole microorganism such as pertussis, (2) an inactivated toxin, called toxoid, such as diphtheria toxoid, or (J) one or more components of the microorganism commonly referred to as subunit vaccines. The examples are capsular polysaccharide of Streptococcus pneumoniae and the surface antigen protein for Hepatitis B vims vaccine. 

Enzyme immunosensors are employed for the determination of Hepatitis B surface antigen, IgG, alpha-fetoprotein, estradiol, theophylline, insulin [9004-10-8] and alburnin (69,70). However, these immunosensors generally have slow response times and slow reversibiUty (57). 

Frye, C. D., and Edidin, M., 1970. The rapid intermixing of cell surface antigens after formation of monse-hnman heterokaryons. of Cell... 

The human leucocyte antigen (HLA) system is the general name of a group of genes in the human major histocompatibility complex (MHC) region on human chromosome 6 (mouse chromosome 17) that encodes the cell-surface antigen-presenting proteins. 

Form protective physical barrier on epithelial surfaces, are involved in cell-cell interactions, and may contain or mask certain surface antigens. 

Drugs frequently bind to blood elements directly (e.g. penicillin to erythrocytes) and the antibodies to the resultant complex react with, and damage, cells coated with the drug. Viruses, especially those that bud, become associated with the host cell surface antigens with the resultant generation of Tc cells. 

Hepatitis Bt Yeast cells genetically modified to express surface antigen 1 Separation of HBsAg from yeast cells 2 Adsorption to AI(0H)3 gel Immunogenicity assay or HBsAg assay by ELISA Test for presence of yeast DMA... 

Influenza (surface antigen) Allantoic fluid from embryonated hens eggs infected with Influenza viruses A and B 1 Inactivation and disruption 2 Separation of haemagglutinin and neuraminidase 3 Blending of haemagglutinins and neuraminidase of different serotypes Assay of haemagglutinin content by immunodiffusion Inoculation of embryonated hens eggs to exclude live virus... 

Hepatitis B surface antigen Monomer has 226 amino acids Yeast Mammalian cells Vaccination Approved for sale Monomer self-assembles into structure resembling virus particles... 

Conventional ion-selective electrodes have been used as detectors for immunoassays. Antibody binding measurements can be made with hapten-selective electrodes such as the trimethylphenylammonium ion electrode Enzyme immunoassays in which the enzyme label catalyzes the production of a product that is detected by an ion-selective or gas-sensing electrode take advantage of the amplification effect of enzyme catalysis in order to reach lower detection limits. Systems for hepatitis B surface antigen and estradiol use horseradish peroxidase as the enzyme label and... 

CDla Isoform a also known as non-classical MHC class I-like surface antigen present on thymocytes and dendritic cells... 

CD lb Known to be present on thymocytes and dendritic cells CDlc Isoform c also known as non-classical MHC class I-like surface antigen present on thymocytes CD2 Defines T cells involved in antigen non-specific cell activation CD3 Also known as T cell receptor-associated surface glycoprotein on T cells CD4 Defines MHC class Il-restricted T cell subsets... 

Tleugabulova, D. Falcon, V., and Penton, E., Physico-chemical characterization of recombinant hepatitis B surface antigen by a multidimensional approach, /. Chromatogr. A, 845, 171, 1999. 

HB, hepatitis B anti-HBs, hepatitis B surface antibody HBsAg, hepatitis B surface antigen HBIG, hepatitis B immune globulin. 

Hepatitis B vaccine is manufactured using recombinant DNA technology to express hepatitis B surface antigen (HBsAg) in yeast. This is further purified with biochemical separation techniques to produce the vaccine. The vaccines are formulated to contain 10 to 40 meg of HBsAg protein/mL. Hepatitis B vaccine is available as a single component or in combination vaccines. 

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