Safety observations

The second type of monitoring Sis are constructed from tools such as (safety) inspections, and (safety) observational programmes. These tools are numerous, van Steen (van Steen, 1996) amongst others provides an overview of many different technical and human based inspections utilized by different companies in the chemical process industry. The aim of this type of tool is to check the presence and effectiveness of technical and human safety measures. This safe way of working is compared with standards (technical and human) and expert opinion to indicate... [Pg.46]

Mazariegos, G.. Kramer, D.. Lopez, R., Shjakil, A., Rosenbloom, A., DeVera, M., Giraldo, M., Grogan, T, Zhu. Y. Fulmer, M., Amiot, B., Patzer, J. Safety observations in phase I clini cal evaluation of Excorp medical bioartificial liver support system after the first four patients. ASAIO J. 47, 471, 2001. [Pg.16]

Neuhaus KL, von Essen R, Tebbe U, etal. Safety observations from the pilot phase of the randomized r-hirudin for improvement of thrombolysis (HIT-111) study. Circulation 1994 90 1638-1642. [Pg.107]

People trying low dosages report feeling disconnected from normal, everyday realities. Blood pressure and pulse are often elevated hypotension and bradycardia have been observed. "Ketamine has a wide margin of safety, observes Parke-Davis brochure "several instances of unintentional administration of overdoses of Ketalar (up to ten times that usually required) have been followed by prolonged but complete recovery. ... [Pg.487]

In addition, prior to SIT departure a special committee performs complex check-up of SIT for purposes of physical protection of nuclear materials (control over technical condition, equipment and fire safety observance of security rules and anti-terrorist preparedness). [Pg.168]

The serious toxicity observed in dogs is not observed in primates A stable IV formulation has now been identified An effective dose and a dosing regimen have been cliaracterized A process to reduce the high cost of goods has been achieved The human safety observed is as predicted... [Pg.432]

Phase II clinical trial studies are designed primarily to explore the relationship between the dose level and frequency of administration and the efficacy and safety observed in patients with a particular therapeutic indication or disorder. Normally, a primary endpoint is selected to evaluate the efficacy however, secondary endpoints are often included to establish criteria for monitoring patients in the more definitive phase III clinical trials. Phase II clinical trials are commonly... [Pg.2499]

Menter A, Gordon K, Carey W, Hamilton T, Glazer S, Caro I, Li N, Gulliver W. Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis. Arch Dermatol 2005 141 31-38. [Pg.197]

The positive trend toward efficacy and the safety observed in these two trials were in good agreement with the preclinical safety and efficacy data obtained in pigs, and they provided the basis to progress the clinical development to larger, multinational phase 2b/3 trials (AGENT-3 and AGENT-4), the results of which will be reported in the future. [Pg.965]

The remarkable clinical safety observed in most cardiovascular gene therapy trials to date [52, 53, 65, 66] is of no coincidence. Lessons learned from past failures at the manufacturing, preclinical efficacy and safety, and clinical development levels were all taken into account in the development of Ad5FGF-4. [Pg.966]

Each employee in a low-temperature plant must be safetyconscious. He must know the procedures to be followed should he detect an unsafe condition emergency procedures must be a part of safety education. Unfortunately, in working closely with a particular system, an individual may overlook a hazardous situation that arises slowly. Accordingly, supervisors must observe operations closely. The National Safety Council suggests the use of a safety observation plan for this purpose.The plan is designed to permit observation of unsafe practices while work is in progress, discussion of these practices, and the enactment of corrective measures before an accident occurs. However, such a plan will work only if all personnel are convinced that it is needed. [Pg.107]

Laitinen, H., Marjamaki, M. and Paivarinta, K. (1999) The validity of the TR safety observation method on building construction. Accident Analysis and Prevention, 315, 463-72. [Pg.75]

Yang Lei Zhang Shuang 2010. Behavior safety observation and communication applying to oil company [J], Secruity Health and Environment 10(10) 13-15. [Pg.740]

A belief that discipline (the safety observation) was a way to motivate individuals and improve safety behaviors. [Pg.107]

Safety Observation Coupon To Safety Observation Coupon To ... [Pg.119]

Figure 8.3 Sample of a safety observation program form.

Participates in the company safety improvement and safety observation programs... [Pg.124]

Safety promotion subteam This subteam s objective is the raising of safety awareness. They would audit and approve safety improvements and track and support the JSA (job safety analysis) efforts. They could also collect the safety observation forms and hold a drawing to select a few winners at all company meetings. Rewards earned through these... [Pg.125]

Complete two safety observations every week. Catch someone working safety and recognize him for his safe behavior. [Pg.136]

At weekly team meetings, review team safety metric performance against target. Metrics could include number of safety observations, safety improvements, or safety JSAs completed. [Pg.137]

Target a number of safety improvements, safety observations, and JSA that will be completed monthly. Review metric results every week at team meeting. [Pg.137]

Start a safety observation program that allows everyone to recognize safe behaviors. Set an annual target. [Pg.143]

Safety observation Someone directly observing someone else while... [Pg.150]

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