Ricinus Ricin

Ricinus Ricin Ricinus communis (Euphorbiaceae) PAG (rat 28S rRNA A4324 in R/S... [Pg.351]

Ricinus Ricin Ricinus communis, R. sanguineus Apoptotic (PAG RIP) (DNA... [Pg.394]

Ricin (toxin from Castor bean Ricinus communis) [A chain 96638-28-7 B chain 96638-29-8] Mr -60,000, amorphous. Crude ricin, obtained by aqueous extraction and (NH4)2S04 pptn, was chromatographed on a galactosyl-Sepharose column with sequential elution of pure ricin. The second peak was due to ricin agglutinin. [Simmons and Russell Anal Biochem 146 206 1985.) Inhibitor of protein synthesis. EXTREMELY DANGEROUS, USE EXTREME CARE [instructions accompany product]. [Pg.565]

Ricinus, m. castor-oil plant, -ijl, n. castor oil. -(ilsaure, /. ricinoleic acid. -Slseife, /. caator-soap, -olsulfosaure, /. castor-oil sulfonic acid, -samen, m. castor bean, -saure, /. ricinic (ricinoleic) acid, -seife, /. castor-oil soap. [Pg.366]

Delayed-action cytotoxin that inhibits protein synthesis (ribosomal inactivating protein) that is obtained from castor beans (Ricinus communis). Waste from production of castor oil contains about 5% ricin by weight. It is a white powder that is soluble in water and relatively heat stable. Aqueous solutions are resistant to chlorine at 10 ppm. It is persistent in the environment. [Pg.482]

Castor oil is derived from the castor plant Ricinus communis). The castor plant has a long and rich history of uses in human society. The oil from the plant is non-digestible, and is commonly known to be a medicinal purgative. The castor bean contains the protein ricin, a substance that is famously toxic in humans [50]. The lack of food value from the castor plant coupled with the issues of toxicity inherent in extraction of ricin has mostly limited the use of castor oil to the industrial sector. [Pg.328]

Lectin toxicity - nausea, diarrhea, headache, confusion, dehydration, death Wisteria, castor bean (Ricinus communis) Lectins bind to cell surfaces Ricin - blocks protein synthesis, very toxic, 5 to 6 beans can kill a child... [Pg.166]

Ricin toxin— Ricinus communis (castor beans)... [Pg.368]

Ricin is a potent cellular protein toxin contained in the beans of the castor been plant (Ricinus communis), which is extensively cultivated for oil production and is also a common ornamental garden plant. Ricin is able to inhibit ribosomal protein synthesis eventually causing cell death, and owing to these properties it has been allegedly used in terrorist and criminal activities. After trypsin digestion of castor bean crude extracts, Ostin et al. [105] were able to unambiguously... [Pg.672]

Ricin (toxin from Castor bean [Ricinus communis]) [96628-29-8]. Crude ricin, obtained by... [Pg.511]

Ricin toxin— Ricinus communis (castor beans) B Castor beans About 8 h Unlikely Standard Fever, N, Cough, chest discomfort, resp difficulty, joint pain, progressing to pulm edema and resp failure Typically fatal w/in 72 h Primarily supportive Tx pulm edema... [Pg.368]

Castor Ricinus communis (Euphorbiaceae) seed 35-55 ricinoleic (80-90), oleic (4-9), linoleic (2-7), palmitic (2-3), stearic (2-3) emollient base, purgative, soap manufacture Castor seeds contain the highly toxic, but heat-labile protein ricin (see page 434)... [Pg.41]

Nicotinic acid undoubtedly provides the basic skeleton for some other alkaloids. Ricinine (Figure 6.35) is a 2-pyridone structure and contains a nitrile grouping, probably formed by dehydration of a nicotinamide derivative. This alkaloid is a toxic constituent of castor oil seeds (Ricinus communis Euphorbiaceae), though the toxicity of the seeds results mainly from the polypeptide ricin (see page 434). Arecoline (Figure 6.36) is found in Betel nuts (Areca catechu Palmae/Arecaceae) and is a tetrahydronicotinic acid derivative. Betel nuts are chewed in India and Asia for the stimulant effect of arecoline. [Pg.314]

Ricin is a heterodimeric glycoprotein (MW = 66 000) produced by the castor bean plant Ricinus communis with the two protein subunits linked by a single disulfide bond. Conditions for the analysis of ricin with CE, using uncoated and coated capillaries as well the influence of buffer systems (run buffer... [Pg.398]

The most toxic plant product, ricin, is also the most toxic chemical known to man. Unlike the pyrrolizidine alkaloids, ricin is a protein which most cleverly targets the interior workings of cells. The way in which this most potent poison works is quite elegant (see box, p. 151). It is made and found in the seeds of the castor bean (Ricinus communis). [Pg.150]

Ricin was found by Stillmark in 1889 as the first plant lectin derived from the seeds of the castor plant, Ricinus communis L., a member of the Euphorbiaceae or spurge family. Other members of this family include the popular houseplants poinsettia E. pulcherrima), and the croton species. The term castor bean is used commonly to refer to both the plant and seed of R. communis. Ricinus communis commonly grows along streams and riverbeds in addition to subtropical locations high in nutrients. Ricinus communis is a coarse perennial, 10-13 m tall in the tropics, with a stem 7.5-15 cm... [Pg.339]

SYNS AFRICAN COFFEE TREE CASTOR BEANS (DOT) CASTOR FLAKE (DOT) CASTOR MEAL (DOT) CASTOR OIL PLANT CASTOR POMACE (DOT) HIGUERETA (CUBA, PUERTO RICO) HIGUERILLA (MEXICO) KOU (HAWAII) LAAU-AILA (HAWAII) MAN S MOTHERWORT MEXICO WEED PA AILA (HAWAII) PALMA CHRISTI (HAITI) RICIN (HAITI) RICINO (PUERTO RICO) RICINUS CO LMUNIS STEADFAST WONDER TREE... [Pg.296]

Castor oil is the fixed oil obtained from the seeds of Ricinus communis (castor) by cold expression. The whole beans contain a variety of substances that are not expressed with the oil, including the toxin ricin (6,7). [Pg.1305]

Ricin, derived from the beans of the castor plant (Ricinus communis) is one of the most potent and easily produced toxins known. Early recognition of these characteristics led the United States to develop ricin as a chemical weapon during World... [Pg.149]

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