NK, Natural Killer

Immune Defense. Figure 2 Cytokines involved in the development of adaptive immune responses in secondary lympoid tissues such as the lymph nodes or spleen. Abbreviations B B-lymphocyte, IFN interferon, Ig immunoglobulin, IL interleukin, NK natural killer cell, TE T-effector (cytotoxic) lymphocyte, TH T-helper lymphocyte... 

Apo E, apolipoprotein E CAD, coronary artery disease FKN, fractalkine MHC, major histocompatibility complex MCP-1, monocyte chemoattractant protein 1 MMPs, matrix metalloproteinases NK, natural killer oxLDL, oxidized LDL RANTES, regulated on activation, normal T cell expressed and secreted VSMCs, vascular smooth muscle cells. 

DC, dendritic cell NK, natural killer Thl, T helper 1 Th2, T helper 2 Treg, T regulatory. 

FIGURE 9.2 Regulation of Immunity by lnterleukin-2 (IL-2). IL-2 production by T cells and DCs supports the proliferation of T cells, B cells, T reg cells, and NK cells, in addition to establishing a bias towards a Type 1 T cell response. IL-2 can also activate monocytes and NK cells, resulting in increased cytotoxicity. DC dendritic cell IL-2 interleukin-2 NK natural killer cell. 

Mo, monocytes Me, macrophage NK, natural killer cell PMN, polymorphonuelear leukocyte B, B-cells DC, dendritic cells Pit, platelet GPI, glyeosylphosphatidylinositol-linked NA, neutrophil antigen. 

Figure 6.32 The basis of type II hypersensitivity reactions. The antigen is part of a cell, which becomes the target for macrophages, NK cells, neutrophils, and complement. Abbreviation NK, natural killer.

Figure 7.81 Antibody-dependent phagocyte-mediated lysis of red cells in penicillin immunotoxicity (type II hypersensitivity). Abbreviation NK, natural killer cell.

T/NK (natural killer) cell lymphomas are much less common in Western countries and much less understood than the B cell lymphomas. Thus, the discussion of these entities will be much briefer. In addition, a significant number of the T/NK lymphomas, such as enteropathy-type T cell lymphoma, hepatosplenic T cell lymphoma, subcutaneous panniculitis-like T cell lymphoma, blastic NK cell lymphoma, T cell granular lymphocytic leukemia, and adult T cell leukemia/ lymphoma, will not be discussed in this review. The reader is advised to consult the recent World Health Organization Classification of Tumours (J2). 

Schematic representation of the hematopoietic cascade in mice and human (hum). All the cells of the hematopoietic system are positive for antigen CD45. Based on this, the dynamics of surface antigen expression along development of different mature cells derived from the hematopoietic stem cell system can be observed. Rounded arrows indicate self-renewal potential. Smooth thinner arrows indicate directions of cellular differentiation. The identification of CDs (clusters definition) and other antigen cell markers are listed in the glossary. (LT-HSC - long term hematopoietic stem cell ST-HSC - short term hematopoietic stem cell MPP - multipotent progenitor CLP - common lymphoid precursor CMP - common myeloid precursor GMP - granulocyte-monocyte precursor MEP - megacaryocyte-erythrocyte precursor T - T lymphocyte B - B lymphocyte NK - natural killer cell DC - dendritic cell).

Figure 32.1. Schematic of the immune system. The immune system is composed of primary lymphoid organs (bone marrow and thymus), secondary lymphoid organs (not shown), and several cell types. In addition, a number of mediators including cytokines, antibodies, and complement regulate and/or are produced by the immune system. Abbreviations Eos, eosinophil Bas, basophil Neut, neutrophil NK, natural killer cell Ag, antigen T, T lymphocyte B, B lymphocyte Cyt T, cytotoxic T lymphocyte Act B, activated B lymphocyte.

NK natural killer cell NMDA N-methyl-D-aspartate. 

Note DTH, delayed hypersensitivity skin response NC, no change NK, natural killer cell PBMC, peripheral blood mononuclear cells P, proliferation M, men W, women mean pertains to mean age. 

Note Studies marked PC (placebo control) included a control group, and others did not. CD, cluster designation IL, interleukin IFN, interferon M, men NC, no change NK, natural killer P, proliferation W, women. 

HTLV, human T cell lymphotropic virus MALT, mucosa-associated lymphoid tissue NK, natural killer WHO, World Health Organization. 

EC, endothelial cells M, monocytes N, neutrophils F, fibroblasts Pit, platelets SMC, smooth muscle cells K, keratinocytes Ep, epithehal cells T, T cells NK, natural killer cells DC, dendritic cells. 

Abbreviations NOAEL, no-observed-adverse-effect level LOAEL, lowest-observed-adverse-effect level NK, natural killer GSH, glutathione. 

HIV human immune deficiency virus HPV human papillomavirus HSV herpes simplex virus ICAM intercellular adhesion molecule IL interleukin IL-la interleukin 1 a LNA locked nucleic acid mRNA messenger RNA NK natural killer PKC protein kinase C ply rC poly ribocytosine PNA peptide nucleic acid poly rl poly ribinosine PTHrP parathyroid hormone-related peptide thermal melting temperature change in relative to DNA TAR transactivator response element VSV vesicular stomatitis virus... 

NK natural killer cells is mixed with preformed small cationic ve- ... 

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