Interferon gamma IFN

Vickers SM, Jhala NC, Ahn EY, McDonald JM, Pan G, Bland KI (2002) Tamoxifen (TMX)/Fas induced growth inhibition ofhuman cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma). Ann Surg 235 872-878... 

Nomura, T., Yasuda, K., Yamada, T., et al. (1999). Gene expression and antitumor effects following direct interferon (IFN)-gamma gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice. Gene Ther., 6(1), 121-129. 

S. Brown,W.N. Rom, and M.D. Weiden. 2004. Aerosolized gamma interferon (IFN-gamma) induces expression of the genes encoding the IFN-gamma-induci-ble 10-kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis. Infect. Immun. 72 1275-1283. 

Dolhain RJ, ter Haar NT, Hoefakker S, et al. Increased expression of interferon (IFN)-gamma together with IFN-y receptor in the rheumatoid synovial membrane compared with synovium of patients with osteoarthritis. Br J Rheumatol 1996 35 24-32. 

Eiedler M, Rodicker E, Salucci V, Lu M, Aurisicchio L, Dahmen U, Jun L, Dirsch O, Putzer BM, Palombo E, Roggendorf M (2004) Helper-dependent adenoviral vector-mediated delivery of woodchuck-specific genes for alpha interferon (IFN-alpha) and IFN-gamma IFN-alpha but not IFN-gamma reduces woodchuck hepatitis virus replication in chronic infection in vivo, J Virol 78 10111-10121... 

Matskevich AA, Cordelier P, Strayer DS (2003) Conditional expression of IFN-alpha and IFN-gamma activated by HBV as genetic therapy for hepatitis B, J Interferon Cytokine Res 23 709-721... 

Vandenbroeck, K., E. Martens, S. D Andrea, and A. Billiau (1993). Refolding and single-step purification of porcine interferon-gamma from Escherichia coli inclusion bodies. Conditions for reconstitution of dimeric IFN-gamma. Eur J Biochem 215(2) 481-486. 

V3. Viallard, J. F., Pellegrin, J. L., Ranchin, V., Schaeverbeke, T., Dehais, J., Longy-Boursier, M., Ragnaud, J. M., Leng. B., and Moreau, J. F., Thl (IL-2, interferon-gamma (IFN-gamma)) and Th2 (IL-10, IL-4) cytokine production by peripheral blood mononuclear cells (PBMC) from patients with systemic lupus erythematosus (SLE). Clin. Exp. Immunol. 115, 189-195... 

Mizuta I, Nishimura M, Mizuta E, Yamasaki S, Ohta M, Kuno S, Ota M (2001) Relation between the high production related allele of the interferon-gamma (IFN-gamma) gene and age at onset of idiopathic Parkinson s disease in Japan. J Neurol Neurosurg Psy-chiatiy 71 818-819. 

GMP, granular membrane protein ODFR, oxygen-derived free radicals ELAM, endothelial leukocyte adhesion molecule IL-1, interleukin-1 TNF-alpha, tumor necrosis factor-alpha ICAM, intercellular adhesion molecule IFN-gamma, interferon -gamma VCAM, vascular cell adhesion molecule LFA, lymphocyte-associated antigen CR, complement receptor. 

Robinson CM, Hale PT, Carhn JM (2005) The role of IFN-gamma and TNF-alpha-responsive regnlatory elements in the synergistic indnction of indoleamine dioxygenase. J Interferon Cytokine Res 25 20-30. 

Three classes of interferon (IFN) have been characterized or (alpha). (beta), and y (gamma) (sec Table 6-6). re-interferons arc glycoproteins derived from human leukocytes, p-Intcrfcrons are glycoproteins derived from fibroblasts and macrophages. They share a receptor with re-interferons, y-Interferons are glycoproteins derived from human T lympho-... 

Feng C, Keisler DH, Fritsche KL. Dietary omega-3 polyunsaturated fatty acids reduce IFN-gamma receptor expression in mice. J Interferon Cytokine Res 1999 19 41 8. 

Wang, X. and Suzuki, Y. (2007). Microglia produces IFN-gamma independently from T-cells during acute toxoplasmosis in the brain. /. Interferon Cytokine Res. 27, 599-695. 

Schiltz PM, Gomez GG, Read SB, Kulprathipanja NV, Kruse CA. Effects of IFN-gamma and interleukin-1 beta on major histocompatibihty complex antigen and intercellular adhesion molecule-1 expression by 9L gliosarcoma relevance to its cyto-lysis by alloreactive cytotoxic T lymphocytes. J Interferon Cytokine Res 2002 22 1209-1216. 

Takeda K, KamanakaM, TanakaT, Kishimoto T, Akira S. Impaired IL-13-mediated functions of macrophages in Stat6-deflcientmice. J Immunol 1996 157 3220-3222. Ohmori Y, Hamilton TA. The interferon-stimulated response element and a kappa B site mediate synergistic induction of murine IP-10 gene transcription by IFN-gamma and TNF-alpha. J Immunol 1995 154 5235-5244. 

Vadrot, N., Legrand, A., Nello, E., Bringuier, A.F, Guillot, R., and Feldmann, G. (2006). Inducible nitric oxide synthase (inos) activity could be responsible for resistance or sensitivity to IFN-gamma-induced aproptosis in several human hepatoma cell lines. J. Interferon. Cytokine Res. 26, 901-913. 

Chester, D.A., McCutcheon, J.A., and Reiss, C.S. (2004). Posttransciiptional Regulation of Neuronal Nitric Oxide Synthase Expression by IFN-gamma. J. Interferon. Cytokine Res. 24, 141-149. 

The additional use of interferon-gamma (IFN-gamma and IL-lbeta) in tumors made of a colon adenocarcinoma chemically induced in a BD IX rat (DHD/K12-PROb) enhanced the anti-tumor effects during lipid A treatment by increasing iNOS activity and NO concentration in tumor tissues (Onier et al. 1999). 

Okamura H, Tsutsi H, Komatsu T, et al. Cloning of a new cytokine that induces IFN-gamma production by T cells [see comments]. Nature 1995 378 88-91. Yoshimoto T, Okamura H, Tagawa YI, Iwakura Y, Nakanishi K. Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells. Proc Natl Acad Sci USA 1997 94 3948-3953. Barnes PJ, Adcock IM. Transcription factors and asthma. Eur Respir J 1998 12 221-234. 

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