Interferon human beta

Clark, J.M. Hirtenstein, M.D. (1981).High yield culture of human fibroblasts on microcarriers a first step in production of fibroblast-derived interferon (human beta interferon), J. Interferon Res.,l,59 -466. [Pg.193]

In addition, stndies evaluating interferon alpha/beta and interlenkin-16 expression have shown snbstantial antiviral effects against HlV-1 in vitro and in a humanized mouse model (Cremer et al. 2000 Lanret et al. 1994 Sanhadji et al. 1997 Zhou etal. 1997). [Pg.284]

Bekisz, J., Schmeisser, H., Hernandez, J., Goldman, N.D., and Zoon, K.C. 2004. Human interferons alpha, beta and omega. Growth Factors 22(4), 243-251. [Pg.238]

Vallbracht, A., Treuner, J., Manncke, K.H. and Niethammer, D. (1982). Autoantibodies against human beta interferon following treatment with interferon. J. Interferon Res. 2 197. [Pg.441]

Smith, G. E., Summers, M. D., and Fraser, M. J. (1983). Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol. Cell Biol. 3, 2156-2165. [Pg.22]

Goodin DS. Treatment of multiple sclerosis with human beta interferon. Int MS J. 2005 12 96-108. [Pg.542]

Rothenfusser, S., V. Hornung, A. Krug, A. Towarowski, A.M. Krieg, S. Endres, and G. Hartmann (2001) Distinct CpG oligonucleotide sequences activate human gamma delta T cells via interferon-alpha/-beta. Eur J Immund 31 3525-3534. [Pg.221]

Farrar JD, Smith JD, Murphy TL, Murphy KM. Recruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2. J Biol Chem 2000 275 2693-2697. [Pg.45]

Biber K, Zuurman MW, Dijkstra IM, Boddeke HW (2002) Chemokines in the brain neuroimmunology and beyond. Curr Opin Pharmacol 2 63-68 Blasko 1, Veerhuis R, Stampfer-Kountchev M, Saurwein-Teissl M, Eikelenboom P, Grubeck-Loebenstein B (2000) Costimulatory effects of interferon-gamma and interleukin-1 beta or tumor necrosis factor alpha on the synthesis of Abetal-40 and Abetal-42 by human astrocytes. Neurobiol Dis 7 682-689... [Pg.291]

Kim MO, Suh HS, Brosnan CF, Lee SC (2004) Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta. J Neurochem 90 297-308... [Pg.371]

Hypersensitivity to natural or recombinant interferon beta, albumin human, or any other component of the formulation. [Pg.2006]

Fertility Impairment Menstrual irregularities were observed in monkeys administered interferon beta-la at a dose 100 times the recommended weekly human dose. Pregnancy Category C. [Pg.2007]

T Yu, Y Xiao, Y Bai, Q Ru, G Luo, MP Dierich, YH Chen. Human interferon-beta inhibits binding of HIV-1 gp41 to lymphocyte and monocyte cells and binds the potential receptor protein P50 for HIV-1 gp41. Immunol Lett 73 19-22, 2000. [Pg.253]

Byhardt, R.W., L. Vaickus, PL. Witt, A.Y Chang, T. McAuliffe, J.E. Wilson, C.A. Lawton, J. Breitmeyer, M.E. Alger, and E.C. Borden, Recombinant human interferon-beta (rHuIFN-beta) and radiation therapy for inoperable non-small cell lung cancer. J Interferon Cytokine Res, 1996. 16(11) 891-902. [Pg.175]

Borden, E.C.,T.E. Hogan, and J.G Voelkel, Comparative antiproliferative activity in vitro of natural interferons alpha and beta for diploid and transformed human cells. Cancer Res, 1982. 42(12) 4948-53. [Pg.175]

Knobler, R.L., J.I. Greenstein, K.P. Johnson, ED. Lublin, H.S. Panitch, K. Conway, S.V. Grant-Gorsen, J. Muldoon, S.G. Marcus, J.C. Wallenberg, et al., Systemic recombinant human interferon-beta treatment of relapsing- remitting multiple sclerosis pilot study analysis and six-year follow-up. J Interferon Res, 1993. 13(5) 333-40. [Pg.175]

Ruzicka, F.J., M.E. Jach, and E.C. Borden, Binding of recombinant-produced interferon beta ser to human lymphoblastoid cells. Evidence for two binding domains. J Biol Chem, 1987. 262(33) 16142-9. [Pg.176]

A. General description Interferon beta-la is produced by Chinese hamster ovary (CHO) cells into which the human interferon beta gene has been introduced. The amino-acid sequence of the recombinant protein produced by these cells is identical to naturally occurring interferon beta. Interferon beta-la is a single-chain glycosylated polypeptide, 166 amino-acid residues in length, with an approximate molecular weight of 22.5 kDa. [Pg.194]

Interferons and cytokines Interferon beta-la, human recombinant product produced in CHO cells Avonex Lyophilized 200ng,30ng, reconstitute in 1 ml IM... [Pg.462]

Interferons and cytokines Interferon beta-lb, human recombinant produced in E. coli Betaseron Lyophilized 32MIU equivalent to 0.3 mg per vial (albumin added as a stabilizer) SC... [Pg.462]

Interferon beta-la, human recombinant product produced in CHO cells... [Pg.488]

Interferons and Interferon beta-lb, Betaseron cytokines human recombinant... [Pg.488]

Interferon beta 1 (human fibroblast reduced), 17-L-serine- interferon betaser, recombinant... [Pg.499]

Interferon beta-lb [FDA USAN INN BAN] 2-166-Interferon betal (human fibroblast rednced), 17-L-serine-[CAS beta is Greek letter]... [Pg.499]

Human interferon-beta crystal structure PDB ID lAUl... [Pg.576]

Avonex (interferon beta- Biogen-Idec la) [CHO-expressed glycoprotein-recombinant human interferon beta-la]... [Pg.309]

Beatseron (interferon-beta-lb) [E. coli expressed recombinant human interferon beta] Berlex, Inc. Lyophilized (0.3 mg single-dose vial)... [Pg.310]

Bielekova B, Richert N, Howard T, Blevins G, et al. 2004. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc Natl Acad Sd. 101 8705-8708. [Pg.122]

Yamazaki K, Kanaji Y, Shizume K, Yamakawa Y, Demura H, Kanaji Y, Obara T, Sato K. Reversible inhibition by interferons alpha and beta of 125I incorporation and thyroid hormone release by human thyroid follicles in vitro. J Clin Endocrinol Metab 1993 77(5) 1439-41. [Pg.672]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...