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Recombinant human G-CSF

Filgrastim is a recombinant human G-CSF (produced in E. coli), approved for chemotherapy-induced neutropenia since 1991. Although the 18.8 kDa recombinant product is not glycosylated and contains an additional N-terminal methionine residue (due to expression in E. coli), it displays biological activity indistinguishable from native G-CSF. The product is presented in freeze-dried format and contains buffer elements as well as sorbitol and Tween as excipients. [Pg.262]

Filgrastim Neupogen Recombinant human G-CSF Growth factor 2/20/1991... [Pg.577]

Sasaki O, Yokoyama A, Uemura S, Fujino S, Inoue Y, Kohno N, Hiwada K. Drug eruption caused by recombinant human G-CSF. Intern Med 1994 33(10) 641-3. [Pg.1552]

USA filgrastim hematopoiesis Neupogen Gran, Granulokine Recombinant human G-CSF, human clone 1034 with an extra N-terminal Met, expressed in E. coli Hematopoiesis... [Pg.477]

Welte K, Bonilla MA, Gillio AP, et al. Recombinant human G-CSF Effects on hematopoiesis in normal and cyclophosphamide treated primates. J. Exp. Med. 1987 165 941-948. [Pg.1768]

Colony-stimulating factor (G-CSF) Recombinant human G-CSF filgrastim (Neupogen) is a 175-amino acid... [Pg.271]

See other pages where Recombinant human G-CSF is mentioned: [Pg.579]    [Pg.271]    [Pg.370]    [Pg.744]    [Pg.49]    [Pg.754]    [Pg.231]    [Pg.375]    [Pg.280]    [Pg.579]    [Pg.1031]    [Pg.31]    [Pg.931]    [Pg.932]    [Pg.132]    [Pg.563]   
See also in sourсe #XX -- [ Pg.367 ]

See also in sourсe #XX -- [ Pg.49 ]



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Recombinant human

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