Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Formulate the Product

Your first real product will usually be made in the laboratory. That is the place to develop the recipe for full scale production. Experimenting in the lab takes much less time and is much cheaper than on a full scale. The laboratory techniques used in product development are no different from those used in chemical research and education. However, there are differences in the way you need to organize experiments. In research and education, you can choose freely which variables you want to investigate. This is not so in product development. In product development you must try to get a feeling for the effect of all important variables. If you miss any, there is a large chance that competitors will find your weak spot. However, you must be clever if you want to investigate everything with limited means and a limited amount of time. [Pg.107]

Design and Development of Biological, Chemical, Food and Pharmaceutical Products J.A. Wesselingh, S. Kiil and M.E. Vigild 2007 John Wiley Sons, Ltd [Pg.107]

O sintered polyester and TGIC Q NOT a molecular mix Q no cross-linking at low J O four parameters  [Pg.110]

That was the introduction. Now you are to find conditions for getting a good film these are to become the full scale production recipe. [Pg.110]

There are several ways to reduce the amount of experimental work, and combining them can be very effective. First try to understand how the product is to work. We have already described that for our example. This helps to split off parts of the work that are independent - parts that can be studied on their own. Another way to reduce the number of experiments is to use models of the process or parts of it to find suitable starting values. Then we have seen that systematic coverage of the design space is not an efficient way of finding the best solution there are better search methods. Finally, it is often possible to do many experiments simultaneously. Together these techniques can reduce the time needed enormously, and that is just as well. [Pg.111]


The reaction of l,2 5,6-di-0-isopropylidene-D-glucofuranose (49), with phosphorus pentachloride was reported in 1926 by Allison and Hixon (I) who formulated the product as 3-chloro-3-deoxy-l,2 5,6-di-0-isopro-pylidene-D-glucofuranose (2% yield). A reinvestigation (93) of the... [Pg.200]

In some instances there is a possibility that the efficacy of these preparations may be compromised by conditions associated with the digestive tract. Most function at pH values approaching neutrality. They would thus display activity possibly in saliva and particularly in the small intestine. However, the acidic conditions of the stomach (where the pH can be below 1.5) may denature some of these enzymes. Furthermore, the ingested enzymes would also be exposed to endogenous proteolytic activities associated with the stomach and small intestine. Some of these difficulties, however, may be at least partially overcome by formulating the product as a tablet coated with an acid-resistant film to protect the enzyme as it passes through the stomach. [Pg.365]

A manufacturer of motoring products planned to market a carburettor and combustion chamber cleaner which would remove oily and other deposits. As a preliminary step in formulating the product, a complete analysis of a cleaner already marketed by a competitor was required. The competitive formulation was stated to include aromatic petroleum distillates and butyl cellosolve. [Pg.509]

All products have carbamazepine as active ingredients. Retard is slow release formulations. The products have different pharmacokinetics and are not bioequivalent. [Pg.103]

An essential part of the development of a new pesticide is establishing a good, dependable formulation. The product s active ingredient and physical properties should remain acceptable for two years or more. These formulations are often subjected to storage conditions of extreme heat, cold, and hiamidity. Once sold to the applicator, the concentrated formulation should dilute easily to field strength and pass freely through conventional spray equipment. [Pg.87]

Nitrosation of mesityl oxide oxime leads to the dioxide 96, correctly formulated by Freeman.119 Earlier workers had formulated the product as a nitrimine128 and as a nitrosonitrone.118 Hypobromite oxidation of 97 leads to the same compound129 (Scheme 35), whereas the 4-bromo analog of 96 has been prepared by base elimination of HBr from a dibromopyrazoline N,N -dioxide precursor.119... [Pg.26]

When one mole of (Ph>P) Pi(C)H.,) is treated with two mdes of BF,. ethylene is quan-Utively released and the BF) is completely consumed. The product consists of a single Compound, which is monomcnc in dkhloromethane solution. Formulate the product and describe the bonding in it. (See Fishwick, M. Noth. H. Petz. W.. Walfbridge. M. G. H. hutrg. Chem. 1976. /5. 490-492.)... [Pg.903]

Example. Cream liqueurs are an example of a food emulsion for which good stability over a period of several years is required. Thus the processes of creaming, flocculation, and coalescence must all be controlled in the formulation. The product must have a cream-like appearance and a relatively high alcohol content. A possible composition might be ... [Pg.311]

In the presence of acids, continued Griess and Harrow,8 at least two other compounds were formed and could be isolated when a reaction mixture similar to that described in their first paper was allowed to stand for a month in a warm place. The less soluble compound mentioned earlier was named anhydrogluco-o-diaminobenzene. It was formed by the condensation of one molecule of glucose with one molecule of o-phenylenediamine two molecules of water and two hydrogen atoms were eliminated during the reaction. They formulated the product N=CH... [Pg.177]

The reaction between [Os3(CO)10(NCMe)2] and [Au(C2Ph)(PPh3)] was first described by Lewis and co-workers (60), but they incorrectly formulated the product as [AuOs3(CO)9(C2Ph)(PPh3)]. [Pg.256]

McDermott and Whitesides (132) have reported that 1,4-dilithiobutane in ether at -78°C reacts with (T)-C5H5)2TiCl2 to yield a reactive organoti-tanium complex stable below — 30°C. They formulated the product as a metallocycle. [Pg.43]

Isolation of Processes To minimize cross-contamination and microbiological contamination, the manufacturer may develop special procedures for the isolation of processes. The level of facilities isolation depends on the types of products to be manufactured. For instance, steroids and sulfas require more isolation than over-the-counter (OTC) oral products [6], To minimize exposure of personnel to drug aerosols and loss of product, a sealed pressure vessel must be used to compound aerosol suspensions and emulsions [21], An example of cross-contamination with steroids was the controversial case of a topical drug manufactured for the treatment of skin diseases. Fligh-performance liquid chromatography/ultraviolet and mass spectrometry (FIPLC/UV, FIPLC/MS) techniques were used by the FDA for the detection of clobetasol propionate, a class 1 superpotent steroid, as an undeclared steroid in zinc pyrithione formulations. The product was forbidden and a warning was widely published [22],... [Pg.320]

You have a concept and the approval to develop it. This part discusses important things to be done - formulating the product and setting up the process with its equipment. You will have started this earlier - here it has to be worked out. [Pg.105]

Formulate the Product I Flowsheet the Process Estimate the Cost. -" I Equip the Process Scale Up... [Pg.205]

Formulate the Product. Make the product in the lab and describe the ingredients and procedure in a recipe. [Pg.206]

CNC Antistat 4 is compatible with finishing agents commonly used in textile finishing and is effective in water repellent formulations. The product is non-corrosive to plant equipment and no special handling is required. [Pg.175]

The importance of alkylperoxy radicals as intermediates had long been realized (see Sect. 2) and their subsequent reaction to yield the alkyl-hydroperoxide or decomposition products such as aldehydes and alcohols had been reasonably successful in describing the mechanism of the autocatalytic oxidation of alkanes. However, even though 0-heterocycles (which cannot be derived from intermediate aldehydes) had been found in the products of the oxidation of n-pentane as early as 1935 [66], the true extent of alkylperoxy radical isomerization reactions has been recognized only recently. Bailey and Norrish [67] first formulated the production of O-heterocycles in terms of alkylperoxy radical isomerization and subsequent cyclization in order to explain the formation of 2,5-dimethyl-tetrahydrofuran during the cool-flame oxidation of n-hexane. Their mechanism was a one-step process which involved direct elimination of OH. However, it is now generally formulated as shown in reactions (147) and(I67)... [Pg.269]

The parent compound azetidine was the first member of the series to be described., In 1888 Gabriel and Weinerobtained sji impure preparation by treatment of y-bromopropylamihe with alkali, and correctly formulated the product as the four-metubered cyclic imine. [Pg.378]

Addition to quinones. Ethyl diazoacetate adds to the more reactive double bond of 1,4-naphthoquinone in warm benzene without loss of nitrogen, possibly by 1,3-di -olar attack of the structure formulated. The products isolated, 3-carboethoxy-... [Pg.918]

Oxiranes. The anion salt (3) reacts with aldehydes or ketones to give oxiranes in good yield. The reaction with acetophenone is formulated. The product (4) is isolated by quenching with water and extraction with an appropriate solvent. The... [Pg.308]

Additives used in formulations have the purpose of improving the flow of the enamel, to improve the thermo-mechanical properties like heat shock, or to give better adhesion of the cured film to the copper surface. Some of the additives have multiple effects. Because these effects are very specific to a given poly(ester-imide) resin and varnish formulation, the product classes are here only enumerated. Phenolics [112,113], epoxies [114,115], and silicones [116] are well known and some of them were claimed. Better understood is the effect of the phenol... [Pg.58]


See other pages where Formulate the Product is mentioned: [Pg.118]    [Pg.347]    [Pg.132]    [Pg.65]    [Pg.144]    [Pg.195]    [Pg.376]    [Pg.25]    [Pg.107]    [Pg.108]    [Pg.110]    [Pg.112]    [Pg.114]    [Pg.116]    [Pg.132]    [Pg.903]    [Pg.1274]    [Pg.1670]    [Pg.1870]    [Pg.65]    [Pg.95]    [Pg.169]    [Pg.84]    [Pg.350]    [Pg.315]   


SEARCH



Formulated products

Industrial Solutions for the Production of Automotive Seats Using Polyurethane Multi-Component Formulations

Product formulation

© 2024 chempedia.info