Ether, incompatibilities with

Note Viscous, odorless, moderately combustible liquid used for mull preparation relatively low toxicity soluble in benzene, chloroform, carbon disulfide, ethers incompatible with oxidizing materials and amines. Synonyms mineral oil, adepsine oil, lignite oil. 

SAFETY PROFILE Poison by ingestion and intraperitoneal routes. May be corrosive to skin, eyes, and mucous membranes. Explosive reaction with ethyl vinyl ether. Incompatible with hydrogen fluoride. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES. 

Crystals, mp 140. One gram dissolves in about 200 ml water. Slightly sol in ale. Insol in ether. Incompatible with alkalies. 

Hydrochloride, CuH CINOj. Small needles from abs ethanol, mp 232° (dec), [ajjf +10°. Unstable in air and light. Bitter taste. Sol in water, benzene, chloroform, methanol. ethannl moderately sol in diethyl ether. Incompat. with oxidizing agents, alkaline solns, and akaloidal reagents. 

Monohydrate, faintly bitter crystals producing transient numbness ol the tongue. Stable in air. When anhydr mp 190-192. One gram dissolves in 50 m] water. Freely so] in boiling water, alcohol, chloroform. Insol in ether. Incompatible with alkalies and their carbonates and the usual alkaloidal reagents. Aq solns are stable and are not dec by boiling. 

CHEMICAL PROPERTIES Will polymerize to plastic when in contact with oxidizers, chlorosLilfonic acid, nitric acid or oleum flammable liquid often contains polymerization inhibitors such as hydroquinone ethers incompatible with oxidizing agents, peroxides, aluminum, copper, sunlight, heat and air FP (-15°C) LFL (6.5%) UFL (15.5%) AT (519°C). 

Precaution Corrosive to iron, steel, brass, copper, lead explosive reaction with ethyl vinyl ether incompat. with hydrogen fluoride, alkalis, amines, vinyl ethers reacts violently with water Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of SO,... 

The polarity of the polyethers makes them incompatible with hydrocarbon-type plasticizers, which tend to bleed. Effective plasticizers are ethers such as di(butoxyethoxyethyl)formal [143-29-3] (Thiokors TP-90B), esters such as di(2-ethylhexyl) phthalate [117-81-7] dioctyl phthalate (DOP), polyesters such as Paraplex G50 (Rohm and Haas), and ether—esters such as di(butoxyethoxyethyl) adipate [114-17-3] (Thiokol s TP-95). The lower mol wt plasticizers, DOP, TP-90B, and TP-95 improve vulcanizate low temperature performance. The polymeric plasticizers maintain higher temperature and long-term aging properties. Epoxidized plasticizers should be avoided because they interfere with vulcanization. 

Other acetal-type protecting groups (tetrahydrofurfuryl ethers, methoxymethyl ethers, 1,3-dioxolanes) are also considered to be incompatible with oxidising agents. 

Although some specific functional groups in these molecules are incompatible with the current method, the fact that 3-formylrifamycin is bound and cleaved in excellent yield demonstrates that several sensitive functionalities (acetal, enol ether, ketone, dienoate) are well tolerated. Various positions of the antibiotic could be acylated selectively. 

In the previous four sections, several solvent radical ions that cannot be classified as molecular ions ( a charge on a solvent molecule ) were examined. These delocalized, multimer radical ions are intermediate between the molecular ions and cavity electrons, thereby bridging the two extremes of electron (or hole) localization in a molecular liquid. While solvated electrons appear only in negative-EAg liquids, delocalized solvent anions appear both in positive and negative-EAg liquids. Actually, from the structural standpoint, trapped electrons in low-temperature alkane and ether glasses [2] are closer to the multimer anions because their stabilization requires a degree of polarization in the molecules that is incompatible with the premises of one-electron models. 

The removal of triglycerides from the food sample by saponification provides the opportunity to utilize reversed-phase chromatography. The unsaponifiable matter is conventionally extracted into a solvent [e.g., diethyl ether/petroleum ether (50 50) or hexane] that is incompatible with a semiaqueous mobile phase. It then becomes necessary to evaporate the unsaponifiable extract to dryness and to dissolve the residue in a small volume of methanol (if methanol is the organic component of the mobile phase). For the analysis of breakfast cereals, margarine, and butter, Egberg et al. (153) avoided the time-consuming extraction of the unsaponifiable matter and the evaporation step by acidifying the unsaponifiable matter with acetic acid in acetonitrile to precipitate the soaps. An aliquot of the filtered extract could then be injected, after dilution with water, onto an ODS column eluted with a compatible mobile phase (65% acetonitrile in water). 

Initial work involved the functionalisation of C as a TBDPS ether (as in 59a) However, this proved to be incompatible with our overall approach. An alternative, and somewhat more direct strategy involved the incorporation of a halogen at C from the outset. This was expected to be entirely compatible with subsequent steps, conveniently undergoing transformation into the corresponding triphenylphosphonium salt at a later stage. Initially, the bromide 59b was chosen and indeed was found to be admirably compatible with the ensuing chemistry. However, during... 

Any increase of polarity of the hydrocarbon, for example by substitution with chlorine or by replacing CH2 groups by ether oxygens, also increases incompatibility with perfluoroalkanes as polar interactions become more important [89, 96]. Polar groups are fundamental constituents of the mesogenic cores, especially as linking units and as substituents at aromatic moieties, and these groups increase the incompatibility between the aromatic cores and Rp-chains. 

N—H, S—H, —C C-H. Grignard reagents are made in ether, and are incompatible with water and acids stronger than water. 

In the previous studies, calixarenes were not directly usable in a liquid-liquid extraction process, because used in a diluent (nitro phenyl hexyl ether), the hydrodynamic properties were incompatible with such a process. The system has been modified in order to satisfy the following criteria density, viscosity, kinetics, and absence of a third phase.102... 

Note Highly polar solvent sweet, ethereal odor soluble in water flammable, burns with a luminous flame highly toxic by ingestion, inhalation and skin absorption miscible with water, methanol, methyl acetate, ethyl acetate, acetone, ethers, acetamide solutions, chloroform, carbon tetrachloride, ethylene chloride, and many unsaturated hydrocarbons immiscible with many saturated hydrocarbons (petroleum fractions) dissolves some inorganic salts such as silver nitrate, lithium nitrate, magnesium bromide incompatible with strong oxidants hydrolyzes in the presence of aqueous bases and strong aqueous acids. Synonyms methyl cyanide, acetic acid nitrile, cyanomethane, ethylnitrile. 

Note Confirmed human carcinogen Nonpolar, aromatic solvent sweet odor very flammable and toxic confirmed human carcinogen soluble in alcohols, hydrocarbons (aliphatic and aromatic), ether, chloroform, carbon tetrachloride, carbon disulfide, slightly soluble in water incompatible with some strong acids and oxidants, chlorine trifluoride (zinc in the presence of steam) decomposes at high temperature to form biphenyl. Synonyms cyclohexatriene, benzin, benzol, phenylhydride. These are the most common, although these are many other synonyms. 

Note Nonpolar solvent soluble in alcohols, ethers, chloroform, benzene, and most fixed and volatile oils insoluble in water nonflammable extremely toxic by inhalation, ingestion, or skin absorption carcinogenic incompatible with allyl alcohol, silanes, triethyldialuminum, and many metals (e.g., sodium). Synonyms tetrachloromethane, perchloromethane, methane tetrachloride, Halon-104. 

Note Polar solvent soluble in alcohols, ether, benzene, and most oils usually stabilized with methanol to prevent phosgene formation flammable and highly toxic by inhalation, ingestion, or skin absorption narcotic carcinogenic incompatible with caustics, active metals, aluminum powder, potassium, sodium, magnesium. Synonyms trichloromethane, methane trichloride. 

Note Moderately polar solvent soluble in water and most organic solvents flammable highly toxic by ingestion and inhalation absorbed through the skin may cause central nervous system depression, necrosis of the liver and kidneys incompatible with strong oxidizers. Synonyms diethylene ether, 1,4-diethylene dioxide, diethylene dioxide, dioxyethylene ether. 

Note Polar solvent soluble in water, alcohols (organic halides), ether, and many oils flammable moderately toxic by inhalation and skin absorption incompatible with strong oxidizers, nitrates, strong alkalis, strong acids. Synonyms acedin, acetic ether, acetic ester, ethyl ethanoate, vinegar naphtha, acetic acid ethyl ester. 

Note Nonpolar solvent soluble in alcohols, hydrocarbons, organic halides, acetone, and ethers insoluble in water flammable moderately toxic by inhalation and ingestion incompatible with strong oxidizers. Synonyms hexane, hexyl hydride. 

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