Combinatorial materials research

Iden R, Schrof W, Hadeler J, Lehmann S (2003) Combinatorial materials research in the polymer industry speed versus flexibility. Macromol Rapid Commun 24 63-72... 

Meier MAR, Schubert US (2006) Selected successful approaches in combinatorial materials research. Soft Matter 2 371-376. This paragraph was partially reproduced by permission of The Royal Society of Chemistry http //dx.doi.org/10.1039/b518304a... 

Meier MAR, Schubert US (2006) Selected successful approaches in combinatorial materials research. Soft Matter 2 371-376... 

Kugel AJ, Jarabek LE, Daniels JW et al. (2009) Combinatorial materials research applied to the development of new surface coatings XII novel, environmentally friendly antimicrobial coatings derived from biocide-functional acrylic polyols and isocyanates. J Coat Technol Res 6 107-121... 

Conventionally, the detailed experimentation with sensing materials candidates for their screening and optimization consumes tremendous amount of time and project cost without adding to the intellectual satisfaction. Fortunately, new synthetic and measurement principles and instrumentation significantly accelerate the development of new materials. The practical challenges in rational sensor material design also provide tremendous prospects for combinatorial materials research. 

Stafslien, S. J. Bahr, J. A. Feser, J. M. Weisz, J. C. Chisholm, B. J. Ready, T. E. Boudjouk, R, Combinatorial materials research applied to the development of new surface coatings I A multiwell plate screening method for the high-throughput assessment of bacterial biofilm retention on surfaces, J. Comb. Chem. 2006, 8, 156-162... 

Early combinatorial materials research used sputtering methods to prepare composition gradient libraries for measuring the phase behavior of ternary metal alloys (20) and other inorganic materials (25). However, limitations in computing capacity and instrument automation overshadowed the benefits of combinatorial... 

One of the major requirements related to combinatorial material research is, however, the preparation of thin films and dots from solution in a fast and reproducible manner. Furthermore, the parallel investigation of the physical properties of these films is required to develop a more detailed understanding and new structure-property relationships. Ink-jet printing can bridge the gap between polymer synthesis and solid-state or surface property evaluation, since the technique opens the way to the automatic preparation of libraries of polymers, polymer blends, and composites, with a systematic variation of parameters such as chemical composition or thickness." ... 

Dovidenko, K. Potyrailo, R. A. Grande, J., Focused ion beam microscope as an analytical tool for nanoscale characterization of gradient formulated polymeric sensor materials, In Combinatorial Methods and Informatics in Materials Science. Materials Research Society Symposium Proceedings Fasolka, M. Wang, Q. Potyrailo, R. A. Chikyow, T. Schubert, U. 

In this artide, we review the new field of combinatorial materials science. We describe in detail our particular materials exploration approach that we call the continuous compositional spread (CCS) approach. This CCS approach allows the synthesis and characterization of a major fraction of a ternary or pseudo-ternary phase spread in about 24 hours. We compare the CCS approach with other schemes for rapid materials investigations. We also provide an example of the successful application of the CCS approach in the discovery of a new high dielectric constant thin-film material, an amorphous zirconium tin titanate, aZTT. New combinatorial approaches to materials research can allow us to do studies that would not have been possible using conventional techniques. 

Webster DC (2008) Combinatorial and high-throughput methods in macromolecular materials research and development. Macromol Chem Phys 209 237-246... 

Meier MAR, Schubert US (2004) Combinatorial polymer research and high-throughput experimentation powerful tools for the discovery and evaluation of new materials. J Mater Chem 14 3289-3299... 

Other scientists besides biomedical researchers have employed combinatorial chemistry. In 1995, X.-D. Xiang and Peter G. Schultz, then at the University of California, Berkeley, and their colleagues published a paper in Science describing a pioneering application of this technique in materials research. As described in A Combinatorial Approach to Materials Discovery, Schultz and his colleagues performed parallel synthesis—a lot of reactions at the same time—to make an ar-... 

Potyrailo, RA, Karim, A, Wang, Q, and Chikyow, T. 2004. Combinatorial and Artificial Intelligence in Materials Science. Warrendale, PA Materials Research Society. 

An exciting new area of materials research that has begun to evolve in recent years is the application of combinatorial chemistry to the creation of thin-film libraries. By using masks (grids with separate squares), thousands of distinct combinations of materials can, in principle, be deposited onto a single substrate in order to greatly accelerate the screening of the resultant compounds for certain properties. This is part of a broad approach... 

Combinatorial and Artificial Intelligence Methods in Materials Science, Takeuchi, I. Newsam, J. M. Wille, L. T. Koinuma, H. Amis, E. J., Eds. Materials Research Society Warrendale, PA, 2002 Vol. 700... 

Special Feature on Combinatorial and High-Throughput Materials Research, Potyrailo, R. A. Takeuchi, I., Ed. Meas. Sci. Technol. 2005 Vol. 16, 316... 

Semancik, S., Temperature-dependent materials research with micromachined array platforms, In Combinatorial Materials Synthesis Xiang, X.-D. Takeuchi, I., Eds. Marcel Dekker New York, NY, 2003 263-295... 

S. Guessasma, G. Montavon, C. Coddet, in I. Takeuchi, J. M. Newsam, L.T. Wille, H. Koinuma, E. J. Amis, eds., MRS Symposium Proceedings. Combinatorial and Arficial Intelligence Methods in Materials Science, Materials Research Society, Warrendale, PA, Vol. 700,253-258 (2002). 

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