Color isopropyl alcohol

Isopropyl alcohol is widely used as a solvent, an antiseptic, and a disinfectant and is commonly available in the home as a 70% solution (rubbing alcohol). It Is often ingested by alcoholics as a cheap substitute for liquor. Unlike the other common alcohol substitutes methanol and ethylene glycol, isopropyl alcohol is not metabolized to highly toxic organic acids and therefore does not produce a profound anion gap acidosis. Hospitals sometimes color isopropyl alcohol with blue dye to distinguish it from other clear liquids this has led abusers to refer to it as blue heaven. ... 

Recovery of the wopropyl alcohol. It is not usually economical to recover the isopropyl alcohol because of its lo v cost. However, if the alcohol is to be recovered, great care must be exercised particularly if it has been allowed to stand for several days peroxides are readily formed in the impure acetone - isopropyl alcohol mixtures. Test first for peroxides by adding 0-6 ml. of the isopropyl alcohol to 1 ml. of 10 per cent, potassium iodide solution acidified with 0-6 ml. of dilute (1 5) hydrochloric acid and mixed with a few drops of starch solution if a blue (or blue-black) coloration appears in one minute, the test is positive. One convenient method of removing the peroxides is to reflux each one litre of recovered isopropyl alcohol with 10-15 g. of solid stannous chloride for half an hour. Test for peroxides with a portion of the cooled solution if iodine is liberated, add further 5 g. portions of stannous chloride followed by refluxing for half-hour periods until the test is negative. Then add about 200 g. of quicklime, reflux for 4 hours, and distil (Fig. II, 47, 2) discard the first portion of the distillate until the test for acetone is negative (Crotyl Alcohol, Note 1). Peroxides generally redevelop in tliis purified isopropyl alcohol in several days. 

In addition to the solvent soluble toners, alkah water-soluble toners have been produced. These types include WST produced by Day-Glo and Aquabest produced by Radiant Color. These toners are dissolved ia water which contains a portion of ammonia and, if necessary, some isopropyl alcohol. These toners can be used as binders or additional binders and other additives can be added to give the ink the desired properties. These toners are condensation-type polymers other than the formaldehyde types. 

Paprika oleoresin (EEC No. E 160c) is the combination of davor and color principles obtained by extracting paprika with any one or a combination of approved solvents acetone, ethyl alcohol, ethylene dichloride, hexane, isopropyl alcohol, methyl alcohol, methylene chloride, and trichloroethylene. Depending on their source, paprika oleoresins are brown—red, slightly viscous, homogeneous Hquids, pourable at room temperature, and containing 2—5% sediment. 

While keeping the collected deuterioammonia at dry ice-isopropyl alcohol temperature, lithium wire (10 mg) is added, followed by a solution of 3/3-hydroxy-5a-cholest-7-en-6-one (161 50 mg) in anhydrous tetrahydrofuran (4 ml). The reaction mixture is stirred for 20 min, the cooling bath is then removed and the ammonia is allowed to boil under reflux for 40 min. A saturated solution of ammonium chloride in tetrahydrofuran is added dropwise until the deep blue color disappears and then the ammonia is allowed to evaporate. The residue is extracted with ether and the organic layer washed with dilute hydrochloric acid and sodium bicarbonate solution and then with water. Drying and evaporation of the solvent gives a semicrystalline residue which is dissolved in acetone and oxidized with 8 N chromic acid solution. After the usual workup the residue is dissolved in methanol containing sodium hydroxide (0.2 g) and heated under reflux for 1 hr to remove any deuterium introduced at C-5 or C-7. (For workup, see section II-B). 

To approximately 20 ml of a 1 1 mixture of toluene (xylene) isopropyl alcohol, add 1 ml of oil-base mud and 75 to 100 ml of distilled water. Add 8 to 10 drops of phenolphthalein indicator solution and stir vigorously with a stirring rod (the use of a Hamilton Beach mixer is suggested). Titrate slowly with H SO, (N/10) until red (or pink) color disappears permanently from the mixture. Report the alkalinity as the number of ml of H SO (N/10) per ml of mud. Lime content may be calculated as... 

Calcium Chloride [25]. Calcium chloride estimation is based on calcium titration. To 20 ml of 1 1 mixture of toluene (xylene) isopropyl alcohol, add a 1-ml (or 0.1-ml, if calcium is high) sample of oil-base mud, while stirring. Dilute the mixture with 75 to 100 ml of distilled water. Add 2 ml of hardness buffer solution and 10 to 15 drops of hardness indicator solution. Titrate mixture with standard versenate solution until the color changes from wine-red to blue. If common standard versenate solution (1 ml = 20 g calcium ions) is used, then... 

TLC is related to paper chromatography (PC) as both use a stationary phase and a liquid phase to move the sample [12]. A common example of PC is the separation of black ink into its individual colors. Because the individual molecules behave differently when exposed to a solvent such as water or isopropyl alcohol, they are retained on the paper at different intervals, creating a visible separation of the individual components. This helps to identify each component in a mixture. 

After 2 to 3 h (the longer the better), remove the paper, quickly mark the solvent front with a pencil, and hang the paper in a fume hood to dry. After drying for 5 to 10 min, spray the developed portion with ninhydrin solution (0.1% ninhydrin in butanol or isopropyl alcohol). Allow to dry for 10 min. Then place it in a drying oven at 100°C for 5 min. Amino acid spots will be violet to blue in color. 

The characteristic end point orange color can be demonstrated by addition of a slight excess of the chromic acid oxidizing reagent to a few milliliters of acetone containing a few drops of isopropyl alcohol. 

Deng JF, Wang JD, Shih TS, et al. 1987. Outbreak of carbon tetrachloride poisoning in a color printing factory related to the use of isopropyl alcohol and air conditioning systems in Taiwan. Am J Ind Med 12 11-19. 

The low-molecular-weight water-soluble fraction of LCP flour was found by thin layer chromatographic methods to contain several flavonoid components. To establish the role of flavonoids in the production of yellow color in biscuits, these components were extracted from LCP and glandless cottonseed flours with 85Z aqueous isopropyl alcohol (which is a better solvent for flavonoids than water). Before removal of the flavonoids, the flours had been treated with petroleum ether to extract residual lipids that could interfere with flavonoid isolation. Extraction of the residual lipids did not significantly alter the color of biscuits prepared with the extracted flours (Figure 7). 

D. 2-Methyl-2-phenyl-4-pentenal (7). A dry, 100-mL three-necked, round-bottomed flask with 14/20 joints is fitted with a magnetic stirrer, reflux condenser, and a rubber septum (Note 16). The flask is charged with 50 nL of anhydrous tetrahydrofuran (Note 17) and cooled to -78°C in a dry ice/isopropyl alcohol bath, and a solution of butyllithium (12.0 mmol) in hexane (Note 18) is added with stirring. To this stirred solution is added dropwise via syringe a solution of 3.06 g (12.0 mmol) of diethyl N-benzylideneaminomethyl phosphonate (5) in 5 it of anhydrous tetrahydrofuran, and the colored solution is stirred an additional hour at -78°C. A solution containing 1.20 g (10.0 mmol) of freshly distilled acetophenone in 5 nL of anhydrous tetrahydrofuran is added dropwise, and the cooling bath is removed. The solution is stirred for 1 hr at room temperature and then at reflux for 2 hr. After the solution is cooled to room temperature, it is poured into a 250-nt round-bottomed flask and the solvents are removed under reduced pressure on a rotary evaporator. The yellow residue is partitioned between... 

To test for peroxides add 0.5 cc. of the isopropyl alcohol to 1 cc. of a 10% potassium iodide solution acidified with 0.5 cc. of dilute (1 5) hydrochloric acid. The test is positive if the yellow color of liberated iodine appears in one minute it is still more sensitive if a few drops of 2% starch solution are added to this iodine solution to give the blue-black starch-iodine color. 

Xanthan Gum occurs as a cream colored powder. It is a high-molecular-weight polysaccharide gum produced by a pure-culture fermentation of a carbohydrate with Xanthomonas campestris, purified by recovery with isopropyl alcohol, dried, and milled. It contains D-glucose and D-mannose as the dominant hexose units, along with D-glucuronic acid and pyruvic acid, and it is prepared as the sodium, potassium, or calcium salt. It is readily soluble in hot or cold water, but it is insoluble in alcohol. Its solutions are neutral. 

Method H (Animal Fats and Vegetable and Marine Oils) Prepare a solvent mixture consisting of equal parts, by volume, of isopropyl alcohol and toluene. Add 2 mL of a 1% solution of phenolphthalein in isopropyl alcohol to 125 mL of the mixture, and neutralize with alkali to a faint but permanent pink color. Weigh accurately the appropriate amount of well-mixed liquid sample indicated in the table below, dissolve it in the neutralized solvent mixture, warming if necessary, and shake vigorously while titrating with 0.1 TV potassium hydroxide to the first permanent pink color of the same intensity as that of the neutralized solvent before mixing with the sample. Calculate the acid value by the formula... 

Procedure Unless otherwise directed in the individual monograph, transfer about 4 g of the sample, previously crushed into small lumps and accurately weighed, into a 250-mL Erlenmeyer flask, and add 100 mL of a 1 3 mixture of toluene-isopropyl alcohol, previously neutralized to phenol-phthalein TS with sodium hydroxide. Dissolve the sample by shaking or heating gently, if necessary, then add about 0.5 mL of phenolphthalein TS, and titrate with 0.5 N or 0.1 N alcoholic potassium hydroxide to the first pink color that persists for 30 s. Calculate the acid number by the formula... 

Ethyl 2-butyrylacetate. In a 1-L, three-necked, round-bottomed flask fitted with a mechanical stirrer, dry nitrogen inlet, and thermometer is placed 19.8 g (0.150 mol) of monoethyl malonate (Note 1), 350 mL of dry tetrahydrofuran (THF, Note 2), and 5 mg of 2,2 -bipyridyl. The solution is cooled to approximately -70°C (in an isopropyl alcohol-dry ice bath) and a 1.6M solution of n-butyllithium in hexane is added from a dropping funnel while the temperature is allowed to rise to approximately — 10°C. Sufficient n-butyllithium is added (approx. 190 mL) until a pink color persists for several minutes (Note 3). The heterogeneous solution is recooled to -65°C and 7.90 mL (7.98 g, 75 mmol) of iso-butyryl chloride (Note 4) is added dropwise over 5 min. The reaction solution is stirred for another 5 min (Note 5) and then poured into a separatory funnel containing 500 mL of ether and 300 mL of cold, 1 N hydrochloric acid (Note 6). The funnel is shaken, the layers are separated, and the organic phase is washed with two 150-mL portions of saturated aqueous sodium bicarbonate, followed by 150 mL of water, and dried over anhydrous sodium sulfate. Removal of the solvents under reduced pressure leaves 11.70 g (98%) of ethyl 2-butyrylacetate (Note 7). The crude product can be distilled at 70-74°C (7 mm) (80% yield, 96% purity by GLC). 

Optical methods have found a wide usage for quantitative determination of medical drugs, like tinidazole [1134,1454], metronidazole [1455-1458], In particular, a spectrophotometric method for the estimation of metronidazole and its benzoate in pure form and in pharmaceutical preparations has been used [1458], The method is based on the development of a stable pink color with potassium hydroxide in methanol-isopropyl alcohol solution which can be quantitatively measured at 370 nm. The authors of the work [1457] have stated that the method proposed by them has less error (3 4%) and is less complicated than the used before. The optical properties of organic luminescent microcrystals on the basis of nitrobenzofurazans have been studied [1459],... 

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