Cocaine dependence

Childress AR, McLellan AT, Ehrman R, et al Classically conditioned responses in opioid and cocaine dependence a role in relapse NIDA Res Monogr 84 23 3, 1988... [Pg.98]

Budney AJ, Radonovich KJ, Higgins ST, et al Adults seeking treatment for marijuana dependence a comparison with cocaine-dependent treatment seekers. Exp Clin Psychopharmacol 6 419 26, 1998... [Pg.176]

More than 40 medications have been investigated but none have shown consistent efficacy for primary cocaine or amphetamine dependence. These medications include dopaminergic agonists, antidepressants, and more recently disulfiram, selegiline, and a cocaine vaccine (see Table 5—2 for summary). Studies have been relatively brief and have focused on abstinence initiation rather than on relapse prevention, but even these modest treatment goals have not been attained. The focus in the discussion that follows is on pharmacotherapies for cocaine dependence, because very few clinical trials have been completed with amphetamine-dependent patients. Furthermore, none of the studies of amphetamine dependence have shown results different from those described for cocaine dependence (Rawson et al. 2002b Srisurapanont et al. 2001). [Pg.194]

George TP, Chawarski MC, Pakes J, et al Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects a preliminary trial. Biol Psychiatry 47 1080-1086, 2000... [Pg.203]

Gonzalez G, Sevarino K, Sofuoglu M, et al Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients results of a randomized pilot study. Addiction 98 1625-1632, 2003... [Pg.203]

Grabowski J, Rhoades H, Elk R, et al Fluoxetine is ineffective for treatment of cocaine dependence or concurrent opiare and cocaine dependence two placebo-controlled double-blind rrials. J Clin Psychopharmacol 15 163—174, 1995... [Pg.203]

Grabowski J, Roache JD, Schmitz JM, et al Replacement medication for cocaine dependence merhylphenidate. J Clin Psychopharmacol 17 485 88, 1997... [Pg.203]

GrabowskiJ, RhoadesH, SchmitzJ,eral Dextroamphetamine for cocaine-dependence treatmenr a double-blind randomized clinical rrial. J Clin Psychopharmacol 21 522-526, 2001... [Pg.203]

Higgins ST, Budney AJ, Bickel WK, er al Incentives improve outcome in outpatient behavioral treatment of cocaine dependence. Arch Gen Psychiarry 51 568-576, 1994... [Pg.204]

Holman BL, Carvalho PA, Mendelson J, er al Brain perfusion is abnormal in cocaine-dependent polydrug users a study using technetium-99m-HMPAO and ASPECT. J Nucl Med 32 1206-1210, 1991... [Pg.204]

Khantzian EJ, Gawin F, Kleber HD, et al Methylphenidate (Ritalin) treatment of cocaine dependence—a preliminary report. J Subst Abuse Treat 1 107—112,1984... [Pg.204]

Kornetsky C Hyporesponsivity of chronic schizophrenic patients to dextroamphetamine. Arch Gen Psychiatry 33 1425—1428, 1976 Kosten TR Pharmacotherapy of cerebral ischemia in cocaine dependence. Drug Alcohol Depend 49 133-144, 1998... [Pg.205]

Kosten TR Pathophysiology and treatment of cocaine dependence, in Neuropsychopharmacology The Fifth Generation of Progress. Edited by Davis KL, Charney D, Coyle JT, et al. Baltimore, MD, Lippincott Williams Wilkins, 2002, pp 1461-1473... [Pg.205]

Kranzler HR, Bauer LO, Hersh D, et al Carbamazepine treatment of cocaine dependence a placebo-controlled trial. Drug Alcohol Depend 38 203-211, 1995 Levin FR, Lehman AF Meta-analysis of desipramine an adjunct in the treatment of cocaine addiction. J Clin Pharmacol 11 374-378, 1991 Lima MS, Reisser AA, Soares BG, et al Antidepressants for cocaine dependence. Cochrane Database Syst Rev 4 CD002950, 2001 Ling W, Shoptaw S, Majewska D Baclofen as a cocaine anti-craving medication a preliminary clinical study 0etter). Neuropsychopharmacology 18 403 04, 1998... [Pg.206]

Margolin A, Kosten TR, Avants SK, et al A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients. Drug Alcohol Depend 40 125— 131, 1995... [Pg.206]

Montoya ID, Levin FR, Fudala PJ, et al Douhle-blind comparison of carbamazepine and placebo for treatment of cocaine dependence. Drug Alcohol Depend 38 213— 219, 1995... [Pg.206]

Schmitz JM, Averill P, Stotts AL, et al Fluoxetine treatment of cocaine-dependent patients with major depressive disorder. Drug Alcohol Depend 63 207-214,2001 Schottenfeld RS, Pakes JR, Oliveto A, et al Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. Arch Gen Psychiatry 54 713-720, 1997... [Pg.207]

Somoza EC, Winhusen TM, Bridge TP, et al An open-label pilot study of methylpheni-date in the treatment of cocaine-dependent patients with adult attention deficit/ hyperactivity disorder. J Addict Dis 23 77—92, 2004 Sora 1, Wichems C, Takahashi N, et al Cocaine reward models conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A 95 7699-7704, 1998 Soral, Hall FS, Andrews AM, etal Molecular mechanisms of cocaine reward combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Nad Acad Sci U S A 98 5300-5305, 2001 Spear J, Alderton D Psychosis associated with prescribed dexamphetamine use 0etter). [Pg.208]

Ziedonis DM, Kosten TR Depression as a prognostic factor for pharmacological treatment of cocaine dependence. Psychopharmacol Bull 27 337-343, 1991... [Pg.209]

Bredt DS, Snyder SEl Nitric oxide, a novel neuronal messenger. Neuron 8 3—11, 1992 Brouette T, Anton R Clinical review of inhalants. Am J Addict 10 79-94, 2001 Brown ES, Nejtek VA, Perantie DC, et al Quetiapine in bipolar disorder and cocaine dependence. Bipolar Disord4 406 11, 2002 Bushnell PJ, Evans EIL, Palmes ED Effects of toluene inhalation on carbon dioxide production and locomotor activity in mice. Fundam Appl Toxicol 5 971-977, 1983... [Pg.305]

Sellers EM, Naranjo CA, Harrison M, et al Diazepam loading simplified treatment of alcohol withdrawal. Clin Pharmacol Ther 34 822-826, 1983 Sharp CW Introduction to inhalant Abuse, in Inhalant Abuse A Volatile Research Agenda (NIDA Research Monograph 129). Edited by Sharp CW, Beuvais F, Spence R. Rockville, MD, National Institute on Drug Abuse, 1992, pp 1-10 Smelson DA, Losonczy MF, Davis CW, et al Risperidone decreases craving and relapses in individuals with schizophrenia and cocaine dependence. Can J Psychiatry 47 671-675, 2002... [Pg.312]

Carroll et al. (2004) conducted another study examining psychotherapy and disulfiram treatment for cocaine dependence. In this randomi2ed, doubleblind, placebo-controlled study, patients (iV=121) were assigned to one of four conditions 1) disulfiram plus CBT 2) disulfiram plus interpersonal therapy (IPT), which addressed adherence to a medical model of psychiatric problems, interpersonal functioning, and supportive therapeutic exploration 3) placebo plus CBT or 4) placebo plus IPT. The patients who received disulfiram reduced their cocaine use, relative to those who received placebo, and the patients who received CBT reduced their cocaine use, relative to those who received IPT. Cocaine abstinence among the patients who received CBT plus placebo was not statistically different from that of the patients who re-... [Pg.352]

Several CM studies have explored interactions between medication and psychosocial treatments for substance use disorders. In a 12-week randomized, double-blind study of buprenorphine-maintained opioid- and cocaine-dependent patients, Kosten et al. (2003a) found that desipramine and CM together led to greater abstinence from cocaine and heroin and more consecutive weeks of abstinence than either treatment individually or placebo. A later... [Pg.353]

Higgins ST, Sigmon SC, Wong CJ, et al Community reinforcement therapy for cocaine-dependent outpatients. Arch Gen Psychiatry 60 1043—1052, 2003 Hopkins JS, Garbutt JC, Poole CL, et al Naltrexone and acamprosate meta-analysis of two medical treatments for alcoholism. Presented at the 25th annual meeting of the Research Society on Alcoholism, San Francisco, CA, June 28—July 3, 2002... [Pg.359]

Rawson RA, Huber A, McCann M, et al A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependence. Arch Gen Psychiatry 59 817—824, 2002 Rohsenow DJ, Monti PM, Martin RA, et al Motivational enhancement and coping skills training for cocaine abusers effect on substance use outcomes. Addiction... [Pg.362]

Stotts AL, Schmitz JM, Rhoades HM, et al Motivational interviewing with cocaine-dependent patients a pilot study. J Consult Clin Psychol 69 858-862, 2001 Volpicelli J, Rhines KC, Rhines JS, et al Naltrexone and alcohol dependence role of subjecr compliance. Arch Gen Psychiarry 54 737—742, 1997 Wilk Al, Jensen NM, Havighurst TC Mera-analysis of randomized control trials addressing brief inrervenrions in heavy alcohol drinkers.) Gen Inrern Med 12 274— 283, 1997... [Pg.363]

There are no proven pharmacotherapies for treatment of cocaine or amphetamine dependence. Disulfiram, however, shows some promise in randomized controlled trials for treating cocaine dependence at doses of 250 mg daily, especially in combination with CBT.45 Its mechanism of action for treating cocaine dependence is not known, but may be due to its inhibition of the dopamine P-hydroxylase enzyme that converts DA to NE in the brain. The resulting increase in DA levels may counter the DA-deficient state that is believed to underlie cocaine withdrawal and craving. [Pg.545]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...