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Randomized, controlled trial

As discussed in Chapter 3, there are challenges in selecting appropriate comparison groups for clinical studies to assess the safety of infant formulas. The gold standard design— the double-blind, randomized, controlled trial—randomly assigns comparable groups of... [Pg.108]

Quinn, J., Drzewiecki, A., Li, M., Stiell, I., Sutcliffe, T., Elmsiie, T. and Wood, W., A randomized, controlled trial comparing a tissue adhesive with suturing in the repair of pediatric facial lacerations. Ann. Emerg. Med., 22, 1130-1135 (1993). [Pg.1126]

Chapman, W., Sherman, R., Boyce, S., Malawer, M., Hill, A., Buncke, G., Block, J., Fung, J., Clavien, R, Lee, K., Lebovic, G., Wren, S., Diethrich, E. and Goldstein, R., A novel collagen-based composite offers effective hemostasis for multiple surgical indications Results of a randomized controlled trial. Surgery, 129, 445-450 (2001). [Pg.1128]

Writing Group for the Women s Health Initiative Investigators (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women principal results from the Women s Health Initiative randomized controlled trial. JAMA 288 321-333... [Pg.393]

Dorus and colleagues (1989) conducted a multicenter, double-blind, placebo-controlled trial in depressed and nondepressed alcoholic veterans. A total of 457 male alcoholic patients, of whom approximately one-third were depressed, were randomly assigned to receive either 600-1,200 mg/day of lithium or a comparable number of placebo capsules. No significant differ-... [Pg.38]

Johnson BA, Ait-DaoudN Neuropharmacological treatments for alcoholism scientific basis and clinical findings. Psychopharmacology (Berl) 149 327—344, 2000 Johnson BA, Roache JD, Javors MA, et al Ondansetron for reduction of drinking among biologically predisposed alcoholic patients a randomized controlled trial. [Pg.46]

Streeton C, Whelan G Naltrexone, a relapse prevention maintenance treatment of alcohol dependence a meta-analysis of randomized controlled trials. Alcohol Alcohol 36 544-552, 2001... [Pg.53]

Dean AJ, Bell J, Mascord DJ, et al A randomized, controlled trial of fluoxetine in methadone maintenance patients with depressive symptoms. J Affect Disord 72 ... [Pg.98]

McRae AL, Sonne SC, Brady KT, et al A randomized, placebo-controlled trial of buspirone for the treatment of anxiety in opioid-dependent individuals. Am J Addict 13 53-63, 2004... [Pg.104]

Seecof R, Tennant FS Subjective perceptions to the intravenous rush of heroin and cocaine in opioid addicts. Am J Drug Alcohol Abuse 12 79—87, 1987 Sees KL, Delucci KL, Masson C, et al Methadone maintenance vs. 180-day psycho-socially enriched detoxification for treatment of opioid dependence a randomized controlled trial. JAMA 283 1303-1310, 2000 Sells SB Treatment effectiveness, in Handbook on Drug Abuse. Edited by Dupont RE, Goldstein A, O Donnell J. Washington, DC, U.S. Government Printing Office, 1979, pp 105-118... [Pg.107]

Strang J, Bearn J, Gossop M Lofexidine for opiate detoxification review of recent randomized and open controlled trials. Am J Addict 8 337—348, 1999... [Pg.108]

Johnson BA, Roache JD, Javors MA, et al Ondansetron for reduction of drinking among biologically predisposed alcoholic patients a randomized controlled trial. [Pg.308]

Fleming MF, Barry KL, Manwell LB, et al Brief physician advice for problem alcohol drinkers a randomized controlled trial in community-based primary care practices. J Am Med Assoc 277 1029-1043, 1997 Goldstein MF, Deren S, Sung-Yeon K, et al Evaluation of an alternative program for MMTP drop-outs impact on treatment re-entry. Drug Alcohol Depend 66 181-187, 2002... [Pg.358]

Stotts AL, Schmitz JM, Rhoades HM, et al Motivational interviewing with cocaine-dependent patients a pilot study. J Consult Clin Psychol 69 858-862, 2001 Volpicelli J, Rhines KC, Rhines JS, et al Naltrexone and alcohol dependence role of subjecr compliance. Arch Gen Psychiarry 54 737—742, 1997 Wilk Al, Jensen NM, Havighurst TC Mera-analysis of randomized control trials addressing brief inrervenrions in heavy alcohol drinkers.) Gen Inrern Med 12 274— 283, 1997... [Pg.363]

Gruzdev B, Rakhmanova A, Doubovskaya E, Yakovlev A, Peelers M, Rinehart A, de Dier K, Baede-van Dijk B, Parys W, van t Klooster G (2003) A randomized, double-bhnd, placebo-controlled trial of TMC125 as 7-day monotherapy in antiretroviral n Ve, HIV-1 infected subjects. AIDS 17 2487-2494... [Pg.172]

Chan HL, Leung NW, Hui AY, Wong VW, Liew CT, Chim AM, Chan FK, Hung LC, Lee YT, Tam JS, Lam CW, Sung JJ (2005b) A randomized, controlled trial of combination therapy for... [Pg.231]

Lampertico P, Del Ninno E, Manzin A, Donato MF, Rumi MG, Lunghi G, Morabito A, Clementi M, Colombo M (1997) A randomized, controlled trial of a 24-month course of interferon alfa 2b in patients with chronic hepatitis B who had hepatitis B virus DNA without hepatitis B e antigen in serum. Hepatology 26 1621-1625... [Pg.236]

Rosina E, Pintus C, Meschievitz C, Rizzedo M (1991) A randomized controlled trial of a 12-month course of recombinant human interferon-alpha in chronic delta (type D) hepatitis a multicenter Italian study. Hepatology 13 1052-1056... [Pg.239]

Berger J, Ring J Efficacy of antihistamine pretreat- 15 ment in the prevention of adverse reactions to Hymenoptera venom immunotherapy a prospective randomized placebo-controlled trial. J Allergy 16 Clin Immunol 1997 100 458-463. [Pg.10]

Strength of recommendation A based on a meta-analysis or at least one randomized controlled trial. Strength of recommendation B based on at least one well-designed study, including case control and comparative studies. Strength of recommendation C based on expert reports or opinion (levels of evidence and strength of recommendation. Oxford (UK) Centre for Evidence-Based Medicine. Available at http //www.cebm.net/levels of evidence.asp (accessed December 8,2008). [Pg.212]

The current evidence base for the injection of epinephrine in the initial acute treatment of anaphylaxis includes clinical experience during nearly a century of use, observational studies, epidemiological studies, fatality studies, and randomized controlled trials in people at risk for anaphylaxis although not actually experiencing it at the time of the study. Moreover, the pharmacology of epinephrine has been... [Pg.213]

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Randomization (randomized trials

Randomized control trials

Randomized trials

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